| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 |
|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||||
Net loss | ||||||||
-201,770 | -180,307 | -164,403 | -165,305 | -153,543 | -146,969 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||
Depreciation and amortization | ||||||||
1,077 | 917 | 759 | 633 | 460 | 297 | 0 | 0 | 0 |
Stock-based compensation expense | ||||||||
25,974 | 20,819 | 24,756 | 37,197 | 33,431 | 30,947 | 0 | 0 | 0 |
In process research and development expenses | ||||||||
5,405 | 3,600 | 2,000 | 10,261 | 29,761 | 49,659 | 0 | 0 | 0 |
Amortization of operating lease right-of-use assets | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Amortization of long-term debt discount and issuance costs | ||||||||
0 | - | - | - | - | - | - | - | - |
Amortization of premium on investments, net of accretion of discounts | ||||||||
0 | - | - | - | - | - | - | - | - |
Net realized gain on investments | ||||||||
0 | - | - | - | - | - | - | - | - |
Changes in operating assets and liabilities: | ||||||||
Prepaid expenses and other current assets | ||||||||
2,706 | 4,393 | 4,192 | 6,779 | 6,205 | 2,827 | 0 | 0 | 0 |
Other assets | ||||||||
-1,495 | -2,714 | -3,125 | -2,747 | -1,985 | 584 | 0 | 0 | 0 |
Operating lease liabilities | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Accounts payable | ||||||||
-1,922 | -1,399 | -1,107 | 2,125 | 3,671 | 2,085 | 0 | 0 | 0 |
Accrued expenses | ||||||||
71 | 1,521 | 1,915 | 2,590 | 4,708 | 5,938 | 0 | 0 | 0 |
Accrued research and development expenses | ||||||||
4,072 | 8,605 | 11,267 | 12,579 | 12,725 | 10,527 | 0 | 0 | 0 |
Accrued compensation and benefits | ||||||||
1,116 | 5,180 | 0 | 0 | 0 | - | - | - | 0 |
Accrued interest expense | ||||||||
- | - | - | - | - | -117 | 0 | 0 | 0 |
Net cash used in operating activities | ||||||||
-169,355 | -144,834 | -125,717 | -105,122 | -75,110 | -51,044 | 0 | 0 | 0 |
Cash flows from investing activities | ||||||||
Research and development asset acquisitions, net of cash acquired | ||||||||
5,405 | 3,600 | 2,000 | 10,261 | 29,897 | 17,721 | 0 | 0 | 0 |
Purchase of marketable securities | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Maturities of marketable securities | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Sales of marketable securities | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Purchase of property and equipment | ||||||||
3,132 | 2,966 | 2,760 | 3,765 | 3,326 | 3,490 | 0 | 0 | 0 |
Net cash provided by (used in) investing activities | ||||||||
79,036 | -147,144 | -202,758 | -325,823 | -353,518 | -144,711 | 0 | 0 | 0 |
Cash flows from financing activities | ||||||||
Proceeds from issuance of common stock | ||||||||
- | 291,311 | 0 | 0 | 0 | - | - | - | - |
Proceeds from the exercise of stock options | ||||||||
1,989 | 2,045 | 0 | 0 | 0 | - | - | - | - |
Proceeds from issuance of convertible preferred stock, net | ||||||||
- | - | - | - | - | - | - | 0 | 0 |
Repayment of notes payable to related parties | ||||||||
- | - | - | - | - | 40 | 0 | 0 | 0 |
Net cash provided by financing activities | ||||||||
30,805 | 321,578 | 317,916 | 547,099 | 520,299 | 300,859 | 0 | 0 | 0 |
Effect of exchange rate changes on cash and cash equivalents | ||||||||
0 | - | - | - | - | - | - | - | - |
Net increase (decrease) in cash and cash equivalents | ||||||||
-59,514 | 29,600 | -10,559 | 116,154 | 91,671 | 105,104 | 0 | 0 | 0 |
Cash paid for interest | ||||||||
0 | - | - | - | - | - | - | - | - |
Supplemental disclosure of noncash investing and financing activities: | ||||||||
Acquisition of in-process research and development through issuance of stock | ||||||||
- | - | - | - | - | 19,284 | 0 | 0 | 0 |
Issuance of Series A convertible preferred stock to convert debt and accrued interest | ||||||||
- | - | - | - | - | 6,124 | 0 | 0 | 0 |
Right-of-use assets obtained in exchange for lease liabilities | ||||||||
- | - | - | - | 0 | - | - | - | - |
Change in unrealized gain (loss) on marketable securities, net of tax | ||||||||
-485 | 331 | 0 | 0 | 0 | - | - | - | - |
Unpaid property and equipment | ||||||||
-496 | 183 | 0 | 0 | 0 | - | - | - | 0 |
Conversion of convertible preferred stock to common stock | ||||||||
- | 338,367 | 0 | 0 | 0 | - | - | - | - |
Employee Stock Purchase Plan | ||||||||
Proceeds from issuance of common stock | ||||||||
0 | - | - | - | - | - | - | - | - |