Ionis pharmaceuticals, inc. (IONS)
Income statement / Quarterly
Mar'20Dec'19Sep'19Jun'19Mar'19Dec'18Sep'18Jun'18Mar'18Dec'17Sep'17Jun'17Mar'17Dec'16Sep'16Jun'16Mar'16Dec'15Sep'15Jun'15Mar'15Dec'14Sep'14Jun'14Mar'14Dec'13Sep'13Jun'13Mar'13Dec'12Sep'12Jun'12Mar'12Dec'11Sep'11Jun'11Mar'11Dec'10Sep'10Jun'10Mar'10Sep'09Jun'09
Revenue:
Revenue

133,367

493,680

167,892

163,813

297,214

192,113

145,395

117,747

144,419

167,792

118,314

112,273

115,800

186,505

110,927

38,470

36,874

51,571

49,121

120,428

62,583

84,861

44,063

57,076

28,161

42,248

23,585

38,092

43,360

19,873

11,601

47,340

23,235

32,403

20,713

24,823

21,147

26,420

28,624

23,503

29,926

26,771

30,992

Expenses:
Cost of products sold

2,548

1,012

967

1,364

1,041

1,820

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sa

116,952

148,740

104,366

106,165

106,417

113,452

95,255

101,830

104,067

128,286

80,214

83,506

82,638

101,152

84,631

77,573

80,964

101,330

88,508

68,007

64,447

67,953

61,086

59,264

53,448

57,430

45,660

42,631

38,312

42,758

36,551

40,435

38,714

47,219

39,924

36,009

34,245

39,333

34,716

39,124

31,987

33,832

32,146

Selling, general and administrative

74,994

83,276

60,036

75,111

68,221

66,059

68,712

66,198

43,653

45,706

26,788

22,317

13,677

18,042

10,188

9,824

10,562

13,181

8,751

7,775

7,466

6,828

4,470

4,462

4,380

4,676

3,430

3,389

3,423

3,234

3,096

3,209

2,976

3,800

3,105

2,874

3,010

2,944

2,855

3,051

2,819

3,335

3,673

Total operating expenses

194,494

233,028

165,369

182,640

175,679

181,331

163,967

168,028

147,720

173,992

107,002

105,823

96,315

119,194

94,819

87,397

91,526

114,511

97,259

75,782

71,913

74,781

65,556

63,726

57,828

62,106

49,090

46,020

41,735

45,992

39,647

43,644

41,690

51,019

43,029

38,883

37,255

42,277

37,571

42,175

34,806

37,167

35,819

Income (loss) from operations

-61,127

260,652

2,523

-18,827

121,535

10,782

-18,572

-50,281

-3,301

-6,200

11,312

6,450

19,485

67,311

16,108

-48,927

-54,652

-62,940

-48,138

44,646

-9,330

10,080

-21,493

-6,650

-29,667

-19,858

-25,505

-7,928

1,625

-26,119

-28,046

3,696

-18,455

-18,616

-22,316

-14,060

-16,108

-15,857

-8,947

-18,672

-4,880

-10,396

-4,827

Other income (expense):
Equity in net loss of Regulus Therapeutics Inc.

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-267

0

-163

-976

-1,279

-386

-1,033

-856

-521

-930

-3,942

-1,486

-

-

Investment income

10,479

13,192

13,136

13,735

12,142

11,477

9,963

5,137

3,610

623

2,811

2,465

2,280

1,560

989

1,466

1,457

1,230

1,384

918

845

679

675

671

657

686

434

589

376

359

408

477

600

518

575

616

705

780

776

859

955

1,430

1,678

Interest expense

10,990

13,365

12,002

11,802

11,599

11,456

11,282

11,113

10,938

10,786

10,825

11,778

11,363

9,934

9,746

9,625

9,490

9,351

9,233

9,127

9,021

7,307

4,998

4,961

4,943

4,885

4,867

4,808

4,795

4,817

5,937

5,219

5,179

5,107

4,773

3,437

3,415

3,396

3,338

3,261

3,237

3,185

3,155

Gain on investments, net

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1,116

3

-260

397

305

175

840

1,058

1,446

0

2

17

4,448

18

34

-318

448

-15

-136

-1,010

123

2,612

Gain on investment in Regulus Therapeutics Inc.

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

20,211

-

-

-

535

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Difference between the purchase price of the facility and the carrying value of our financing liability at the time of the purchase.

-

-

-

-

-

-

-

-

-

-

-7,689

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Loss on early retirement of debt

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-4,770

-

-

-

-

-

-

-

-

-

-

-

-

Other expenses

-99

-354

-140

-45

-147

-37

-22

45

-168

-2,845

-2,141

0

1,438

0

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Income (loss) before income tax benefit (expense)

-61,737

238,260

3,517

-16,939

121,931

10,766

-19,913

-56,212

-10,797

-16,332

-6,532

-2,863

8,964

54,954

7,351

-57,086

-62,685

-71,061

-35,776

36,437

-17,506

15,643

-25,278

-11,200

-33,556

-23,752

-29,763

-11,307

-1,736

-11,042

-38,345

-1,207

-23,993

-20,036

-26,882

-17,880

-19,992

-13,895

-12,454

-25,152

-9,658

-12,028

-3,692

Income tax benefit (expense)

-3,300

34,307

-14,900

-6,900

31,000

-292,056

500

400

15

-7,163

961

222

0

2,933

0

-231

232

372

0

789

-789

-15,410

1,398

881

-2,276

524

-5,193

-1,181

-64

-8,405

-706

0

2

0

0

9

2

-

-

2

-

724

-11

Net loss from continuing operations

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-12,752

-3,681

Gain on sale of Ibis Biosciences, Inc., net of tax

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

34

94

Net income from discontinued operations, net of tax

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

34

94

Net income (loss)

-58,480

203,958

18,432

-10,012

90,884

302,732

-20,365

-56,570

-10,812

-9,169

-7,493

-3,085

8,964

-

7,351

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-12,718

-3,587

Net (income) loss attributable to noncontrolling interest in Akcea Therapeutics, Inc.

-10,254

19,543

-7,732

-9,136

6,441

-17,343

-15,806

-16,215

-9,392

-6,247

-4,882

0

0

-

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-1,136

-857

Net income (loss) attributable to Ionis Pharmaceuticals, Inc. common stockholders

-48,226

184,416

26,163

-876

84,443

320,075

-4,559

-40,355

-1,420

-2,922

-2,611

-3,085

8,964

52,021

7,351

-56,855

-62,917

-71,433

-35,776

35,648

-16,717

31,053

-26,676

-12,081

-31,280

-24,276

-24,570

-10,126

-1,672

-2,637

-37,639

-1,207

-23,995

-20,036

-26,882

-17,889

-19,994

-13,985

-12,454

-25,154

-9,658

-11,582

-2,730

Basic and diluted net loss per share (in dollars per share)

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-0.47

-

-

-

-

-0.14

-

-0.23

-

-0.27

-0.23

-0.21

-0.09

-0.02

-0.03

-0.37

-0.01

-0.24

-0.20

-0.27

-0.18

-0.20

-

-

-

-

-

-

Shares used in computing basic and diluted net loss per share (in shares)

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

120,798

-

-

-

-

118,948

-

117,811

-

117,128

116,331

115,263

108,539

101,875

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Net loss from continuing operations attributable to Isis Pharmaceuticals, Inc. common stockholders, Basic (in dollars per share)

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-0.12

-0.03

Basic net income per share (in dollars per share)

-0.35

1.31

0.19

-0.01

0.63

2.42

-0.03

-0.29

-0.01

0.12

-0.02

-0.02

0.07

-

0.06

-

-0.52

-

-0.30

0.30

-

-

-

-0.10

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-0.13

-0.25

-0.10

-0.12

-0.03

Shares used in computing basic net income (loss) per share (in shares)

139,429

140,612

140,551

140,247

138,582

137,892

137,346

128,712

125,330

124,844

124,370

123,989

122,861

-

120,989

-

120,598

-

119,979

119,742

-

-

-

117,588

-

-

-

-

-

-

100,680

100,213

100,157

99,766

99,687

99,602

99,569

99,272

99,196

99,091

99,013

98,320

98,116

Net loss from continuing operations attributable to Isis Pharmaceuticals, Inc. common stockholders, Diluted (in dollars per share)

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-0.12

-0.03

Diluted net income per share (in dollars per share)

-0.35

1.29

0.18

-0.01

0.62

2.40

-0.03

-0.29

-0.01

0.12

-0.02

-0.02

0.07

-

0.06

-

-0.52

-

-0.30

0.29

-

-

-

-0.10

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-0.13

-0.25

-0.10

-0.12

-0.03

Shares used in computing diluted net income (loss) per share (in shares)

139,429

146,296

143,408

140,247

141,537

144,836

137,346

128,712

125,330

131,061

124,370

123,989

124,972

-

123,378

-

120,598

-

119,979

127,779

-

-

-

117,588

-

-

-

-

-

-

100,680

100,213

100,157

99,766

99,687

99,602

99,569

99,272

99,196

99,091

99,013

98,320

98,116

Commercial [Member]
Revenue

83,961

100,364

95,699

88,299

68,088

72,945

82,756

57,198

42,023

53,908

34,617

23,688

7,801

3,078

2,014

16,015

1,660

679

203

770

691

2,323

265

448

8,611

598

327

477

1,689

3,543

474

200

1,417

721

524

518

1,133

983

839

2,360

1,370

809

224

Royalty revenues from the sale of SPINRAZA (nusinersen).
Revenue

66,008

81,107

81,672

70,502

59,711

70,186

70,010

56,653

41,081

52,073

32,890

22,366

5,211

883

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Revenue from the sale of TEGSEDI (inotersen).
Revenue

15,159

13,689

11,945

9,865

6,754

2,237

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Revenue from license fees and other royalties, excluding royalties from the sale of SPINRAZA.
Revenue

2,794

5,568

2,082

7,932

1,623

522

12,746

545

942

1,835

1,727

1,322

2,590

2,195

2,014

16,015

1,660

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Revenue from research and development services performed under a collaboration agreement.
Revenue

49,406

393,316

72,193

75,514

229,126

119,168

62,639

60,549

102,396

113,884

83,697

88,585

107,999

183,427

108,913

22,455

35,214

50,892

48,918

119,658

61,892

82,538

43,798

56,628

19,550

41,650

23,258

37,615

41,671

16,330

11,127

47,140

21,818

31,682

20,189

24,305

20,014

25,437

27,785

21,143

28,556

25,962

30,768