| Dec'19 | Dec'18 | Dec'17 | ||||
|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||
Net loss | ||||||
-103,130 | -77,056 | -29,406 | ||||
Adjustments to reconcile net loss to cash used in operating activities: | ||||||
Depreciation | ||||||
152 | 136 | 65 | ||||
Share-based compensation expense | ||||||
2,173 | 1,290 | 392 | ||||
Gain on short-term investments | ||||||
125 | 423 | - | ||||
Non-cash gain on short-term investments | ||||||
- | 278 | -44 | ||||
Interest on short-term investments | ||||||
5 | 40 | 95 | ||||
Amortization of debt discount and deferred financing costs | ||||||
362 | 360 | - | ||||
Issuance of ordinary shares under subscription agreement | ||||||
3,037 | 1,362 | - | ||||
Other | ||||||
-752 | -362 | - | ||||
Changes in operating assets and liabilities: | ||||||
Prepaid expenses and other current assets | ||||||
-2,471 | 3,613 | 3,815 | ||||
Other assets | ||||||
1,166 | 2,273 | 782 | ||||
Accounts payable | ||||||
11,446 | 849 | 1,671 | ||||
Accrued expenses | ||||||
5,851 | 3,072 | 1,236 | ||||
Income taxes | ||||||
123 | 120 | 6 | ||||
Other liabilities | ||||||
-826 | 242 | 80 | ||||
Net cash used in operating activities | ||||||
-78,885 | -75,890 | -30,604 | ||||
Cash flows from investing activities: | ||||||
Purchases of property and equipment | ||||||
24 | 90 | 812 | ||||
Purchases of short-term investments | ||||||
- | 96,493 | 53,275 | ||||
Proceeds from sale of short-term investments | ||||||
40,125 | 87,925 | 22,500 | ||||
Net cash provided by investing activities | ||||||
40,101 | -8,658 | -31,587 | ||||
Cash flows from financing activities: | ||||||
Proceeds from issuance of debt, net of debt issuance costs | ||||||
- | 14,507 | - | ||||
Repayments of long-term debt | ||||||
1,034 | - | - | ||||
Proceeds from issuance of ordinary shares on initial public offering, net of issuance costs | ||||||
- | 74,153 | - | ||||
Proceeds from exercise of share options | ||||||
60 | 7 | - | ||||
Net cash provided by financing activities | ||||||
-974 | 120,842 | 45,867 | ||||
Effect of exchange rates on cash and cash equivalents | ||||||
-22 | -108 | - | ||||
Net increase in cash, cash equivalents and restricted cash | ||||||
-39,780 | 36,186 | -16,324 | ||||
Supplemental Disclosure of Cash Flow Information: | ||||||
Income tax paid—U.S. | ||||||
414 | 352 | 439 | ||||
Interest paid | ||||||
1,399 | 809 | - | ||||
Series B Convertible Preferred Shares | ||||||
Proceeds from issuance of convertible preferred shares | ||||||
- | 32,175 | 45,867 | ||||