| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | ||
|---|---|---|---|---|---|---|
Product revenues, net | ||||||
6,074 | - | - | - | - | ||
Revenue | ||||||
- | - | - | 0 | 45 | ||
Costs and expenses: | ||||||
Cost of product revenues | ||||||
2,008 | - | - | - | - | ||
Selling, general and administrative | ||||||
65,015 | 35,431 | 10,867 | - | - | ||
Research and development | ||||||
27,275 | 29,290 | 29,008 | 25,029 | 11,382 | ||
General and administrative | ||||||
- | - | - | 7,640 | 4,609 | ||
Total costs and expenses | ||||||
94,298 | 64,721 | 39,875 | 32,669 | 15,991 | ||
Loss from operations | ||||||
-88,224 | -64,721 | -39,875 | -32,669 | -15,946 | ||
Other income (expense): | ||||||
Interest income | ||||||
2,357 | 1,687 | 527 | 147 | - | ||
Interest expense | ||||||
8,480 | 3,314 | 1,019 | 767 | 604 | ||
Loss on extinguishment of debt | ||||||
- | -390 | - | - | - | ||
Change in fair value of warrant liability | ||||||
- | - | 1,844 | -122 | 132 | ||
Total other expense | ||||||
-6,123 | -2,017 | -2,336 | -498 | -736 | ||
Net loss | ||||||
-94,347 | -66,738 | -42,211 | -33,167 | -16,682 | ||
Net loss per share—basic and diluted | ||||||
-2.76 | -2.49 | -3.71 | -28.07 | -14.89 | ||
Weighted average shares outstanding—basic and diluted | ||||||
34,209 | 26,753 | 11,375 | 1,181 | 1,120 | ||