| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
Net product revenues | ||||||
4,256 | 1,966 | 0 | - | - | - | - |
Revenue from Contract with Customer, Including Assessed Tax | ||||||
- | - | - | 0 | - | - | - |
Operating costs and expenses: | ||||||
Cost of product revenues | ||||||
587 | 324 | 0 | 0 | - | - | - |
Research and development | ||||||
28,310 | 26,399 | 17,665 | 13,861 | 19,412 | 18,694 | 3,140 |
Selling, general and administrative | ||||||
37,926 | 26,499 | 13,988 | 8,308 | 7,850 | 8,539 | 1,079 |
Restructuring costs | ||||||
- | - | - | 655 | 0 | 0 | - |
Total operating costs and expenses | ||||||
66,823 | 53,222 | 31,653 | - | - | - | - |
Total operating costs and expenses | ||||||
- | - | - | 22,824 | 27,262 | 27,233 | 4,219 |
Loss from operations | ||||||
-62,567 | -51,256 | -31,653 | -22,824 | -27,262 | -27,233 | -4,219 |
Interest and other income, net | ||||||
1,178 | 1,566 | 774 | 325 | 132 | 94 | - |
Interest and other income, net | ||||||
- | - | - | - | - | - | 6 |
Net loss | ||||||
-61,389 | -49,690 | -30,879 | -22,499 | -27,130 | -27,139 | -4,213 |
Change in unrealized gains or losses on available-for-sale securities | ||||||
-24 | -20 | 0 | -19 | 23 | 27 | - |
Change in unrealized gains or losses on available-for-sale securities | ||||||
- | - | - | - | - | - | 0 |
Comprehensive loss | ||||||
-61,365 | -49,670 | -30,879 | -22,480 | -27,153 | -27,166 | -4,213 |
Net loss per share, basic and diluted (in usd per share) | ||||||
-1.59 | -1.60 | -1.23 | -1.13 | -1.37 | -1.44 | -1.13 |
Weighted-average number of common shares outstanding, basic and diluted (in shares) | ||||||
38,657 | 31,001 | 25,084 | 19,873 | 19,773 | 18,782 | 3,732 |