| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
Revenue | ||||||
12,839 | 0 | - | - | - | - | - |
Revenue | ||||||
- | - | - | 0 | 0 | 0 | 0 |
Operating expenses: | ||||||
Royalty and direct contract acquisition costs | ||||||
2,945 | - | - | - | - | - | - |
Research and development | ||||||
19,415 | 41,759 | 20,593 | 20,472 | 13,931 | 11,917 | 3,367 |
General and administrative | ||||||
10,816 | 12,508 | 12,773 | 14,000 | 8,883 | 4,526 | 1,351 |
Severance expense | ||||||
- | 1,636 | - | 3,010 | 0 | 0 | - |
Total operating expenses | ||||||
33,176 | 55,903 | - | - | - | - | - |
Total operating expenses | ||||||
- | - | 33,366 | 37,482 | 22,814 | 16,443 | 4,718 |
Loss from operations | ||||||
-20,337 | -55,903 | -33,366 | -37,482 | -22,814 | -16,443 | -4,718 |
Other (expense) income: | ||||||
Gain on extinguishment of debt | ||||||
- | 2 | - | -4,740 | 0 | 1,900 | - |
Interest expense related to amortization of debt issuance costs and discount | ||||||
1,656 | 1,618 | 1,561 | 1,616 | 1,909 | 1,114 | 1,560 |
Interest expense on principal | ||||||
4,858 | 5,469 | 5,776 | 5,511 | 2,671 | 1,605 | 157 |
Fair value adjustment related to derivative and warrant liability | ||||||
-1,998 | -5,976 | 3,091 | -32,465 | 27,276 | 7,223 | -1,137 |
Interest and other income, net | ||||||
309 | 420 | 365 | 353 | 32 | 8 | 52 |
Total other (expense) income | ||||||
-4,207 | -689 | -10,063 | 20,951 | -31,824 | -8,034 | -528 |
Loss before income taxes | ||||||
-24,544 | -56,592 | -43,429 | -16,531 | -54,638 | -24,477 | -5,246 |
Income tax benefit | ||||||
-22 | -126 | -43 | -15 | 26 | -22 | -20 |
Net loss | ||||||
-24,522 | -56,466 | -43,386 | -16,516 | -54,664 | -24,455 | -5,226 |
Net loss per share of common stock: | ||||||
Basic and diluted (in dollars per share) | ||||||
-0.83 | -3.15 | -2.96 | -1.13 | -7.42 | -10.27 | -2.20 |
Weighted average number of shares of common stock outstanding: | ||||||
Basic and diluted (in shares) | ||||||
29,654 | 17,930 | 14,652 | 14,597 | 7,368 | 2,381 | 2,381 |