| Dec'19 | Dec'18 | Dec'17 | Dec'16 | |||
|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||
Net loss | ||||||
-47,365 | -41,443 | -27,936 | -17,132 | |||
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Depreciation | ||||||
538 | 490 | 549 | 257 | |||
Non-cash interest expense and amortization of debt discount and issuance cost | ||||||
0 | 5,482 | 1,161 | 0 | |||
Change in fair value of redeemable convertible preferred stock warrant liability | ||||||
0 | 2,700 | 1,260 | 0 | |||
Change in fair value of derivative instrument | ||||||
0 | 1,988 | 0 | 0 | |||
Extinguishment of debt | ||||||
- | -5,479 | - | - | |||
Stock-based compensation | ||||||
6,110 | 2,665 | 275 | 272 | |||
Amortization (accretion) of premium (discount) on marketable securities | ||||||
241 | - | - | - | |||
Amortization of operating lease right-of-use asset | ||||||
373 | - | - | - | |||
Changes in assets and liabilities: | ||||||
Prepaid expenses and other current assets | ||||||
168 | 1,995 | -368 | -270 | |||
Other assets | ||||||
4,511 | 0 | -8 | -35 | |||
Accounts payable | ||||||
1,569 | -2,323 | 2,282 | 23 | |||
Accrued and other current liabilities | ||||||
4,932 | -2,105 | 4,330 | 242 | |||
Operating lease liability | ||||||
-383 | - | - | - | |||
Other liabilities | ||||||
0 | 31 | 48 | -14 | |||
Net cash used in operating activities | ||||||
-39,146 | -29,031 | -17,655 | -16,047 | |||
Cash flows from investing activities | ||||||
Purchase of property and equipment | ||||||
437 | 78 | 209 | 771 | |||
Deposits on property and equipment | ||||||
- | 503 | - | - | |||
Purchase of marketable securities | ||||||
150,961 | - | - | - | |||
Maturities of marketable securities | ||||||
14,400 | - | - | - | |||
Net cash used in investing activities | ||||||
-136,998 | -581 | -209 | -771 | |||
Cash flows from financing activities | ||||||
Proceeds from issuance of common stock, net of offering costs | ||||||
297,616 | 83,755 | - | - | |||
Proceeds from issuance of common stock upon options exercise | ||||||
2,287 | 49 | 3 | 5 | |||
Payments for restricted stock units, net of taxes withheld | ||||||
132 | - | - | - | |||
Payments for repurchase of early exercised stock options | ||||||
- | - | - | 4 | |||
Proceeds from issuance of convertible notes (includes $9,560 and $8,000 from related parties for the years ended December 31, 2018 and 2017, respectively) | ||||||
0 | 33,000 | 10,000 | 0 | |||
Debt issuance cost | ||||||
0 | 140 | 181 | 0 | |||
Principal payments of capital lease | ||||||
48 | 108 | 97 | 62 | |||
Principal payments of tenant improvement allowance payable | ||||||
36 | 85 | 88 | - | |||
Principal payments of tenant improvement allowance payable | ||||||
- | - | - | 59 | |||
Net cash provided by financing activities | ||||||
299,687 | 116,471 | 9,637 | -120 | |||
Net increase (decrease) in cash, cash equivalents and restricted cash | ||||||
123,543 | 86,859 | -8,227 | -16,938 | |||
Supplemental cash flow information: | ||||||
Cash paid for interest | ||||||
8 | 19 | 24 | 6 | |||
Supplemental disclosures of non-cash investing and financing information: | ||||||
Operating lease right-of-use asset obtained in exchange for operating lease liability | ||||||
2,163 | - | - | - | |||
Unpaid offering costs | ||||||
459 | 205 | - | - | |||
Offering costs paid in restricted stock awards | ||||||
- | 91 | - | - | |||
Purchase of property and equipment under accounts payable | ||||||
- | - | - | 731 | |||
Derivative instrument related to convertible notes | ||||||
- | 6,603 | - | 0 | |||
Redeemable convertible preferred stock warrant issued in connection with convertible notes | ||||||
0 | 0 | 1,040 | 0 | |||
Acquisition of equipment through capital lease | ||||||
0 | 0 | 73 | 246 | |||