| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 |
|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||||
Net loss | ||||||||
-24,392 | -15,616 | -12,380 | -11,385 | -7,984 | -14,662 | -10,452 | -7,409 | -8,920 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||
Depreciation | ||||||||
120 | 133 | 145 | 130 | 130 | 123 | 123 | 122 | 122 |
Non-cash interest expense and amortization of debt discount and issuance cost | ||||||||
- | - | - | - | - | 187 | 1,962 | 1,870 | 1,463 |
Change in fair value of redeemable convertible preferred stock warrant liability | ||||||||
- | - | - | - | - | 0 | 995 | 80 | 1,625 |
Change in fair value of derivative instrument | ||||||||
- | - | - | - | - | 74 | 1,150 | 438 | 326 |
Stock-based compensation | ||||||||
6,082 | 1,936 | 1,773 | 1,244 | 1,157 | 1,116 | 800 | 657 | 92 |
Amortization (accretion) of premium (discount) on marketable securities | ||||||||
125 | 46 | 77 | 100 | 18 | - | - | - | - |
Amortization of operating lease right-of-use asset | ||||||||
98 | - | - | - | 90 | - | - | - | - |
Amortization of issuance costs | ||||||||
9 | - | - | - | - | - | - | - | - |
Changes in assets and liabilities: | ||||||||
Prepaid expenses and other current assets | ||||||||
133 | 1,950 | -1,934 | 135 | 17 | 1,492 | 238 | 175 | 90 |
Operating lease right-of-use asset | ||||||||
- | - | - | - | - | - | 0 | 0 | 0 |
Other assets | ||||||||
1,602 | 146 | 306 | 4,059 | 0 | - | - | - | - |
Accounts payable | ||||||||
1,887 | 949 | -722 | 748 | 594 | -569 | 91 | -462 | -1,383 |
Accrued and other current liabilities | ||||||||
228 | 3,452 | 1,939 | 655 | -1,114 | 1,406 | 574 | 417 | -4,502 |
Operating lease liability | ||||||||
-104 | -102 | -96 | -140 | -45 | - | - | - | - |
Other liabilities | ||||||||
- | - | - | - | - | -2 | 11 | 14 | 8 |
Net cash used in operating activities | ||||||||
-17,932 | -11,293 | -7,696 | -12,950 | -7,207 | -8,340 | -4,984 | -4,448 | -11,259 |
Cash flows from investing activities | ||||||||
Purchase of property and equipment | ||||||||
180 | 153 | 158 | 119 | 7 | 22 | 18 | 38 | 0 |
Purchase of available-for-sale securities | ||||||||
- | - | - | - | - | - | 0 | 0 | 0 |
Purchase of marketable securities | ||||||||
86,317 | - | - | - | 23,865 | - | - | - | - |
Maturities of marketable securities | ||||||||
19,300 | - | - | - | - | - | - | - | - |
Net cash used in investing activities | ||||||||
-67,197 | -113,283 | -523 | 680 | -23,872 | -525 | -18 | -38 | 0 |
Cash flows from financing activities | ||||||||
Proceeds from issuance of common stock, net of offering costs | ||||||||
- | - | - | - | - | 83,706 | 49 | 0 | 0 |
Proceeds from issuance of common stock upon options exercise | ||||||||
159 | - | - | - | 83 | - | - | - | - |
Proceeds from sale of future royalties, net of issuance costs | ||||||||
99,643 | - | - | - | - | - | - | - | - |
Proceeds from issuance of convertible notes (includes $9,560 and $8,000 from related parties for the years ended December 31, 2018 and 2017, respectively) | ||||||||
- | - | - | - | - | 0 | 0 | 0 | 33,000 |
Deferred offering costs | ||||||||
- | - | - | - | - | - | 1,047 | 635 | 133 |
Debt issuance cost | ||||||||
- | - | - | - | - | 0 | 0 | 0 | 140 |
Principal payments of capital lease | ||||||||
5 | 7 | 7 | 7 | 27 | 27 | 27 | 27 | 27 |
Principal payments of tenant improvement allowance payable | ||||||||
9 | - | - | - | 9 | - | - | - | - |
Principal payments of tenant improvement allowance payable | ||||||||
- | - | - | - | - | - | - | 24 | 23 |
Net cash provided by financing activities | ||||||||
99,788 | 299,340 | 285 | 15 | 47 | 85,529 | -1,049 | -686 | 32,677 |
Net increase (decrease) in cash, cash equivalents and restricted cash | ||||||||
14,659 | 174,764 | -7,934 | -12,255 | -31,032 | 76,664 | -6,051 | -5,172 | 21,418 |
Supplemental disclosures of non-cash investing and financing information: | ||||||||
Operating lease right-of-use asset obtained in exchange for operating lease liability | ||||||||
- | - | - | - | 2,163 | - | - | - | - |
Unpaid offering costs | ||||||||
- | - | - | - | - | -1,372 | 282 | -394 | 1,689 |
Purchase of property and equipment under accounts payable | ||||||||
- | - | - | 27 | 110 | - | - | - | - |
Derivative instrument related to convertible notes | ||||||||
- | - | - | - | - | 0 | 0 | 0 | 6,603 |