| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 |
|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||||
Net loss | ||||||||
-63,773 | -47,365 | -46,411 | -44,483 | -40,507 | -41,443 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||
Depreciation | ||||||||
528 | 538 | 528 | 506 | 498 | 490 | 0 | 0 | 0 |
Non-cash interest expense and amortization of debt discount and issuance cost | ||||||||
- | - | - | - | - | 5,482 | 0 | 0 | 0 |
Change in fair value of redeemable convertible preferred stock warrant liability | ||||||||
- | - | - | - | - | 2,700 | 0 | 0 | 0 |
Change in fair value of derivative instrument | ||||||||
- | - | - | - | - | 1,988 | 0 | 0 | 0 |
Stock-based compensation | ||||||||
11,035 | 6,110 | 5,290 | 4,317 | 3,730 | 2,665 | 0 | 0 | 0 |
Amortization (accretion) of premium (discount) on marketable securities | ||||||||
348 | 241 | 0 | 0 | 0 | - | - | - | - |
Amortization of operating lease right-of-use asset | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Amortization of issuance costs | ||||||||
0 | - | - | - | - | - | - | - | - |
Changes in assets and liabilities: | ||||||||
Prepaid expenses and other current assets | ||||||||
284 | 168 | -290 | 1,882 | 1,922 | 1,995 | 0 | 0 | 0 |
Operating lease right-of-use asset | ||||||||
- | - | - | - | - | - | 0 | 0 | 0 |
Other assets | ||||||||
6,113 | 4,511 | 0 | 0 | 0 | - | - | - | - |
Accounts payable | ||||||||
2,862 | 1,569 | 51 | 864 | -346 | -2,323 | 0 | 0 | 0 |
Accrued and other current liabilities | ||||||||
6,274 | 4,932 | 2,886 | 1,521 | 1,283 | -2,105 | 0 | 0 | 0 |
Operating lease liability | ||||||||
-442 | -383 | 0 | 0 | 0 | - | - | - | - |
Other liabilities | ||||||||
- | - | - | - | - | 31 | 0 | 0 | 0 |
Net cash used in operating activities | ||||||||
-49,871 | -39,146 | -36,193 | -33,481 | -24,979 | -29,031 | 0 | 0 | 0 |
Cash flows from investing activities | ||||||||
Purchase of property and equipment | ||||||||
610 | 437 | 306 | 166 | 85 | 78 | 0 | 0 | 0 |
Purchase of available-for-sale securities | ||||||||
- | - | - | - | - | - | 0 | 0 | 0 |
Purchase of marketable securities | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Maturities of marketable securities | ||||||||
0 | - | - | - | - | - | - | - | - |
Net cash used in investing activities | ||||||||
-180,323 | -136,998 | -24,240 | -23,735 | -24,453 | -581 | 0 | 0 | 0 |
Cash flows from financing activities | ||||||||
Proceeds from issuance of common stock, net of offering costs | ||||||||
- | - | - | - | - | 83,755 | 0 | 0 | 0 |
Proceeds from issuance of common stock upon options exercise | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Proceeds from sale of future royalties, net of issuance costs | ||||||||
0 | - | - | - | - | - | - | - | - |
Proceeds from issuance of convertible notes (includes $9,560 and $8,000 from related parties for the years ended December 31, 2018 and 2017, respectively) | ||||||||
- | - | - | - | - | 33,000 | 0 | 0 | 0 |
Deferred offering costs | ||||||||
- | - | - | - | - | - | 0 | 0 | 0 |
Debt issuance cost | ||||||||
- | - | - | - | - | 140 | 0 | 0 | 0 |
Principal payments of capital lease | ||||||||
26 | 48 | 68 | 88 | 108 | 108 | 0 | 0 | 0 |
Principal payments of tenant improvement allowance payable | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Principal payments of tenant improvement allowance payable | ||||||||
- | - | - | - | - | - | - | 0 | 0 |
Net cash provided by financing activities | ||||||||
399,428 | 299,687 | 85,876 | 84,542 | 83,841 | 116,471 | 0 | 0 | 0 |
Net increase (decrease) in cash, cash equivalents and restricted cash | ||||||||
169,234 | 123,543 | 25,443 | 27,326 | 34,409 | 86,859 | 0 | 0 | 0 |
Supplemental disclosures of non-cash investing and financing information: | ||||||||
Operating lease right-of-use asset obtained in exchange for operating lease liability | ||||||||
- | - | - | - | 0 | - | - | - | - |
Unpaid offering costs | ||||||||
- | - | - | - | - | 205 | 0 | 0 | 0 |
Purchase of property and equipment under accounts payable | ||||||||
- | - | - | 0 | 0 | - | - | - | - |
Derivative instrument related to convertible notes | ||||||||
- | - | - | - | - | 6,603 | 0 | 0 | 0 |