| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 |
|---|---|---|---|---|---|---|---|---|---|
Revenue | |||||||||
Net product sales | |||||||||
23,054 | 10,056 | 0 | 0 | - | - | - | - | - | - |
Contract revenue - related party | |||||||||
- | - | 0 | 616 | 1,057 | 0 | 0 | - | - | - |
Total revenue | |||||||||
23,054 | 10,056 | 0 | 616 | 1,057 | 0 | 0 | - | - | - |
Operating expenses | |||||||||
Cost of product sales | |||||||||
2,392 | 1,643 | 0 | 0 | - | - | - | - | - | - |
Research and development | |||||||||
85,329 | 117,302 | 84,575 | 62,288 | 29,092 | 9,944 | 4,362 | 1,353 | 177 | 13 |
Selling, general and administrative | |||||||||
45,134 | 85,162 | 30,852 | 16,700 | - | - | - | - | - | - |
Selling, general and administrative | |||||||||
- | - | - | - | 13,934 | 11,396 | 13,579 | 9,386 | 2,097 | 3,915 |
Total operating expenses | |||||||||
132,855 | 204,107 | 115,427 | 78,988 | 43,026 | 21,340 | 17,941 | 10,739 | 2,274 | 3,928 |
Loss from operations | |||||||||
-109,801 | -194,051 | -115,427 | -78,372 | -41,969 | -21,340 | -17,941 | -10,739 | -2,274 | -3,928 |
Interest expense | |||||||||
10,774 | 7,303 | - | - | - | - | - | - | - | - |
Interest expense | |||||||||
- | - | 0 | 0 | - | - | - | - | - | - |
Interest income | |||||||||
2,128 | 1,885 | 624 | 187 | - | - | - | - | - | - |
Other income—related party | |||||||||
1,939 | 0 | - | - | - | - | - | - | - | - |
Total other income (expense), net | |||||||||
-6,707 | -5,418 | - | - | - | - | - | - | - | - |
Adjustments to fair value of derivative liabilities | |||||||||
- | - | - | - | - | - | - | 2,998 | - | - |
Fair value of derivative liabilities in excess of proceeds | |||||||||
- | - | - | - | - | - | - | - | - | -5,015 |
Adjustments to fair value of derivative liabilities | |||||||||
- | - | - | - | - | - | - | - | -9,508 | 5,347 |
Financing transaction costs | |||||||||
- | - | - | - | - | - | - | - | - | 163 |
Interest income | |||||||||
- | - | 624 | 187 | 57 | 27 | 6 | 4 | 234 | -1 |
Net loss | |||||||||
-116,508 | -199,469 | -114,803 | -78,185 | -41,912 | -21,313 | -17,935 | -7,737 | -11,548 | -3,760 |
Convertible preferred stock dividends earned | |||||||||
- | - | - | - | - | - | 801 | 780 | 119 | 466 |
Net loss attributable to common shareholders | |||||||||
- | - | - | - | -41,912 | -21,313 | -18,736 | -8,517 | -11,667 | -4,226 |
Net loss per share, basic and diluted (usd per share) | |||||||||
-4.30 | -7.85 | -5.41 | -4.54 | -2.68 | -2.00 | -12.16 | -41.77 | -31.59 | -5.00 |
Weighted-average common shares outstanding - basic and diluted (in shares) | |||||||||
27,112 | 25,422 | 21,215 | 17,228 | 15,651 | 10,667 | 1,540 | 203,924 | 369 | - |