| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|---|
Revenues: | ||||||||||
Net product revenue | ||||||||||
- | - | - | - | 0 | - | - | - | - | - | - |
Collaborative agreements | ||||||||||
289,231 | 36,271 | 75,621 | 79,101 | 129,728 | 22,593 | 2,109 | 783 | 1,632 | 4,191 | 9,334 |
Royalties and other revenue | ||||||||||
511 | 355 | 178 | 155 | 286 | 261 | 113 | 306 | 217 | 717 | 1,366 |
Total revenues | ||||||||||
322,073 | 63,209 | 91,689 | 79,256 | 130,014 | 22,854 | 2,222 | 1,089 | 1,849 | 4,908 | 10,700 |
Operating expenses: | ||||||||||
Cost of sales (including finite-lived intangible asset amortization) | ||||||||||
3,231 | 2,491 | 1,899 | 0 | 0 | - | - | - | - | - | - |
Research and development, including stock-based compensation of $2,176 and $1,768, respectively | ||||||||||
91,924 | 100,243 | 152,223 | 163,973 | 95,187 | 89,279 | 89,682 | 82,574 | 91,828 | 78,520 | 81,238 |
Earnings Per Share, Diluted | ||||||||||
1.16 | -1.14 | -1.17 | - | - | - | - | - | - | - | - |
Selling, general and administrative expenses, included stock-based compensation of $2,256 and $1,643, respectively | ||||||||||
56,835 | 63,754 | 66,090 | 43,157 | 23,835 | 19,411 | 17,121 | 17,043 | 17,350 | 19,396 | 19,418 |
Increase in fair value of Symphony Icon, Inc. purchase liability | ||||||||||
0 | 0 | 2,101 | -703 | 5,927 | 1,428 | -2,210 | 9,887 | 6,766 | 2,710 | 0 |
Impairment loss on buildings | ||||||||||
- | - | - | - | 3,597 | 13,102 | 0 | - | - | - | - |
Total operating expenses | ||||||||||
180,628 | 166,488 | 222,313 | 206,427 | 128,546 | 123,220 | 104,593 | 109,504 | 115,944 | 100,626 | 100,656 |
Loss from operations | ||||||||||
141,445 | -103,279 | -130,624 | -127,171 | 1,468 | -100,366 | -102,371 | -108,415 | -114,095 | -95,718 | -89,956 |
Gain on investments, net | ||||||||||
- | - | - | - | - | - | - | - | - | 141 | 1,173 |
Interest income | ||||||||||
- | - | - | - | - | - | - | 213 | 255 | 519 | 880 |
Interest expense | ||||||||||
20,676 | 20,777 | 6,984 | 6,567 | 6,722 | 2,253 | 1,971 | 2,114 | 2,528 | 2,719 | 2,966 |
Interest and other income, net | ||||||||||
3,350 | 3,508 | 1,954 | 2,293 | 572 | 2,255 | 216 | 105 | 153 | -4,024 | -2,550 |
Net income (loss) before taxes | ||||||||||
124,119 | -120,548 | -135,654 | -131,445 | -4,682 | -100,364 | -104,126 | - | - | -101,801 | -93,419 |
Income tax benefit | ||||||||||
-6,000 | 0 | -12,700 | 0 | 0 | - | - | - | - | - | - |
Income tax benefit | ||||||||||
- | - | - | - | 0 | -70 | 0 | - | - | -26 | -102 |
Consolidated net loss | ||||||||||
- | - | - | - | - | - | - | - | - | - | -93,317 |
Less: net loss attributable to Symphony Icon, Inc. | ||||||||||
- | - | - | - | - | - | - | - | - | - | -10,537 |
Net loss | ||||||||||
130,133 | -120,548 | -122,993 | -131,445 | -4,682 | -100,294 | -104,126 | -110,211 | -116,215 | -101,775 | -82,780 |
Net loss per common share, Basic and Diluted | ||||||||||
1.23 | -1.14 | -1.17 | - | - | - | - | - | - | - | - |
Net loss per common share, basic and diluted | ||||||||||
- | - | - | -1.27 | -0.05 | -1.31 | -1.42 | -0.23 | -0.34 | -0.34 | -0.57 |
Other comprehensive loss: | ||||||||||
Unrealized gain on investments | ||||||||||
96 | 210 | -27 | 24 | -156 | -65 | -21 | 2 | 16 | 5 | - |
Comprehensive loss | ||||||||||
130,229 | -120,338 | -123,020 | -131,421 | -4,838 | -100,359 | -104,147 | -110,209 | -116,199 | -101,770 | - |
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill) | ||||||||||
28,600 | 0 | 0 | - | - | - | - | - | - | - | - |
Weighted Average Number of Shares Outstanding, Diluted | ||||||||||
116,747 | 105,830 | 105,237 | 103,863 | 103,591 | 76,347 | 73,302 | 489,707 | 340,761 | 302,844 | 145,465 |
Weighted Average Number of Shares Issued, Basic | ||||||||||
106,218 | 105,830 | 105,237 | - | - | - | - | - | - | - | - |