| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 | Dec'13 | Sep'13 | Jun'13 | Mar'13 | Sep'12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenues: | |||||||||||||||||||||||||||||
Revenues | |||||||||||||||||||||||||||||
13,682 | 25,192 | 18,741 | 10,593 | 9,662 | 15,794 | 20,798 | 18,834 | 4,695 | 152,358 | 1,663 | 1,666 | 2,055 | 5,106 | 3,255 | 80,673 | 2,846 | 8,178 | 14,681 | 6,716 | 71,279 | 5,476 | 18,382 | 9,220 | 14,719 | 14,906 | 20,232 | 12,298 | 10,598 | 16,081 |
Costs and expenses: | |||||||||||||||||||||||||||||
Research and development | |||||||||||||||||||||||||||||
48,894 | 51,957 | 44,852 | 51,440 | 47,060 | 46,925 | 46,218 | 52,014 | 45,670 | 38,986 | 40,984 | 34,461 | 32,801 | 31,109 | 30,296 | 33,340 | 27,346 | 30,044 | 24,103 | 22,660 | 21,464 | 19,650 | 18,632 | 17,335 | 14,569 | 14,348 | 11,088 | 11,049 | 10,096 | 11,968 |
General and administrative | |||||||||||||||||||||||||||||
10,233 | 11,890 | 11,833 | 12,122 | 10,219 | 10,547 | 9,584 | 11,134 | 9,235 | 8,404 | 8,403 | 8,384 | 7,462 | 9,235 | 7,224 | 7,239 | 6,133 | 6,715 | 6,021 | 5,346 | 4,683 | 4,845 | 3,678 | 4,145 | 3,258 | 3,765 | 1,986 | 1,503 | 3,832 | 1,514 |
Total costs and expenses | |||||||||||||||||||||||||||||
59,127 | 63,847 | 56,685 | 63,562 | 57,279 | 57,472 | 55,802 | 63,148 | 54,905 | 47,390 | 49,387 | 42,845 | 40,263 | 40,344 | 37,520 | 40,579 | 33,479 | 36,759 | 30,124 | 28,006 | 26,147 | 24,495 | 22,310 | 21,480 | 17,827 | 18,113 | 13,074 | 12,552 | 13,929 | 13,482 |
Loss from operations | |||||||||||||||||||||||||||||
-45,445 | -38,655 | -37,944 | -52,969 | -47,617 | -41,678 | -35,004 | -44,314 | -50,210 | 104,968 | -47,724 | -41,179 | -38,208 | -35,238 | -34,265 | 40,094 | -30,633 | -28,581 | -15,443 | -21,290 | 45,132 | -19,019 | -3,928 | -12,260 | -3,108 | -3,206 | 7,158 | -254 | -3,331 | 2,598 |
Other income | |||||||||||||||||||||||||||||
721 | 8,259 | -6,687 | 21,202 | 2,600 | -2,966 | 975 | 1,070 | 674 | 758 | 681 | 525 | 553 | 455 | 419 | 370 | 270 | 130 | 1 | -86 | -3 | 1 | 0 | 1 | 0 | 1 | -554 | -40 | -34 | 1 |
Net loss | |||||||||||||||||||||||||||||
-44,724 | -30,396 | -44,631 | -31,767 | -45,017 | -44,644 | -34,029 | -43,244 | -49,536 | 105,726 | -47,043 | -40,654 | -37,655 | -34,783 | -33,846 | 40,464 | -30,363 | -28,451 | -15,442 | -21,376 | 45,129 | -19,018 | -3,928 | -12,259 | -3,108 | -3,205 | 6,604 | -294 | -3,365 | 2,600 |
Other comprehensive income: | |||||||||||||||||||||||||||||
Unrealized gain on investments | |||||||||||||||||||||||||||||
56 | -7 | -11 | 34 | 3 | -3 | -18 | 40 | 39 | -34 | 56 | 25 | -26 | -100 | -41 | 7 | 57 | -5 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - |
Comprehensive loss | |||||||||||||||||||||||||||||
-44,668 | -30,403 | -44,642 | -31,733 | -45,014 | -44,647 | -34,047 | -43,204 | -49,497 | 105,692 | -46,987 | -40,629 | -37,681 | -34,883 | -33,887 | 40,471 | -30,306 | -28,456 | -15,442 | -21,376 | 45,129 | - | - | - | - | - | - | - | - | - |
Basic and diluted net loss per common share (in usd per share) | |||||||||||||||||||||||||||||
-0.91 | -0.61 | -0.91 | -0.65 | -0.99 | -1.01 | -0.81 | -1.03 | -1.34 | 2.96 | -1.28 | -1.14 | -1.08 | - | -0.97 | - | -0.88 | - | - | - | - | - | - | - | - | - | - | -0.24 | -2.93 | - |
Basic and diluted weighted average common shares outstanding (in shares) | |||||||||||||||||||||||||||||
49,012 | 48,976 | 48,902 | 48,845 | 45,606 | 42,371 | 42,239 | 42,153 | 36,936 | 36,857 | 36,779 | 35,784 | 34,958 | - | 34,766 | - | 34,503 | - | - | - | - | - | - | - | - | - | - | 1,219 | 1,148 | - |
Basic net income (loss) per common share (in usd per share) | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1.17 | - | - | -0.46 | -0.71 | 1.53 | - | -0.14 | -0.44 | -0.12 | - | 0.14 | - | - | 0.00 |
Diluted net income (loss) per common share (in usd per share) | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1.12 | - | - | -0.46 | -0.71 | 1.42 | - | -0.14 | -0.44 | -0.12 | - | 0.01 | - | - | 0.00 |
Basic weighted average common shares outstanding (in shares) | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 34,616 | - | - | 33,339 | 30,059 | 29,415 | - | 27,751 | 27,651 | 26,262 | - | 1,184 | - | - | 1,092 |
Diluted weighted average common shares outstanding (in shares) | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 36,017 | - | - | 33,339 | 30,059 | 31,684 | - | 27,751 | 27,651 | 26,262 | - | 21,242 | - | - | 21,502 |
Revenue From Collaborative Agreements | |||||||||||||||||||||||||||||
Revenues | |||||||||||||||||||||||||||||
12,967 | 24,556 | 17,984 | 9,987 | 9,497 | 14,974 | 20,617 | 18,552 | 4,501 | 152,081 | 1,076 | 1,081 | 1,278 | 4,178 | 2,014 | 78,497 | 1,893 | 7,924 | 14,681 | 5,598 | 71,165 | 5,378 | 18,283 | 9,202 | 14,401 | 14,737 | 20,111 | 11,838 | 10,066 | 15,532 |
Revenue From Government Agreements | |||||||||||||||||||||||||||||
Revenues | |||||||||||||||||||||||||||||
715 | 636 | 757 | 606 | 165 | 820 | 181 | 282 | 194 | 277 | 587 | 585 | 777 | 928 | 1,241 | 2,176 | 953 | 254 | 0 | 1,118 | 114 | 98 | 99 | 18 | 318 | 169 | 121 | 460 | 531 | 548 |