| Dec'19 | Dec'18 | Dec'17 | Dec'16 | |||
|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||
Net loss | ||||||
-76,769 | -57,515 | -35,491 | -9,431 | |||
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Stock-based compensation expense | ||||||
10,001 | 10,703 | 2,259 | 662 | |||
Depreciation and amortization expense | ||||||
1,843 | 875 | 376 | 6 | |||
Loss on disposal of property and equipment | ||||||
- | -67 | - | - | |||
Net amortization (accretion) of premiums (discounts) on marketable securities | ||||||
1,009 | 190 | - | - | |||
Non-cash interest expense | ||||||
- | - | - | 163 | |||
License fees paid in common and preferred stock | ||||||
- | - | 9,275 | 318 | |||
Consultant fees paid in common stock | ||||||
- | - | - | 157 | |||
Changes in operating assets and liabilities: | ||||||
Prepaid expenses and other current assets | ||||||
1,363 | 1,811 | 895 | 41 | |||
Accounts payable | ||||||
145 | 2,500 | -1,125 | 1,006 | |||
Accrued expenses and other current liabilities | ||||||
5,089 | 2,239 | 3,342 | 631 | |||
Deferred rent | ||||||
-4,960 | -1,246 | - | - | |||
Other assets | ||||||
- | - | 4 | - | |||
Net cash used in operating activities | ||||||
-57,103 | -41,886 | -22,263 | -6,529 | |||
Cash flows from investing activities: | ||||||
Purchases of property and equipment | ||||||
3,060 | 7,672 | 2,199 | 139 | |||
Proceeds from sale of property and equipment | ||||||
- | 12 | - | - | |||
Purchases of marketable securities | ||||||
144,371 | 84,043 | - | - | |||
Maturities of marketable securities | ||||||
148,963 | - | - | - | |||
Net cash provided by (used in) investing activities | ||||||
1,532 | -91,703 | -2,199 | -139 | |||
Cash flows from financing activities: | ||||||
Proceeds from public offerings, net of underwriting discounts and commissions | ||||||
60,874 | 93,000 | - | - | |||
Proceeds from issuance of redeemable convertible preferred stock | ||||||
- | 52,300 | 71,695 | 4,305 | |||
Proceeds from issuance of convertible notes payable | ||||||
- | - | - | 6,500 | |||
Payments of public offering costs | ||||||
598 | 3,094 | - | - | |||
Payments of redeemable convertible preferred stock issuance costs | ||||||
- | 88 | 213 | 107 | |||
Proceeds from issuance of common and restricted stock | ||||||
- | - | 4 | 13 | |||
Proceeds from exercise of common stock options | ||||||
2,021 | 29 | - | - | |||
Net cash provided by financing activities | ||||||
62,297 | 142,147 | 71,486 | 10,711 | |||
Net increase (decrease) in cash, cash equivalents and restricted cash | ||||||
6,726 | 8,558 | 47,024 | 4,043 | |||
Supplemental disclosure of non-cash investing and financing activities: | ||||||
Purchase of property and equipment included in accounts payable and accrued expenses | ||||||
- | 1,538 | - | 375 | |||
Conversion of redeemable convertible preferred stock to common stock | ||||||
- | 144,739 | - | - | |||
Accretion of redeemable convertible preferred stock to redemption value | ||||||
- | 88 | 213 | 107 | |||
Cumulative dividends on Series A redeemable convertible preferred stock | ||||||
- | - | 437 | 197 | |||
Reversal of cumulative dividends on Series A redeemable convertible preferred stock | ||||||
- | - | 634 | - | |||
Conversion of notes payable and accrued interest into redeemable convertible preferred stock | ||||||
- | - | - | 7,164 | |||
Other receivable from investor for redeemable convertible preferred stock | ||||||
- | - | - | 6,250 | |||