| Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 |
|---|---|---|---|---|---|---|---|---|
Revenue | ||||||||
Total revenue | ||||||||
96,430 | 33,864 | 0 | - | - | - | - | - | - |
Contract research | ||||||||
- | - | - | - | 9,609 | 3,477 | - | - | - |
License | ||||||||
- | - | - | - | 4,339 | 4,335 | - | - | - |
Supply | ||||||||
- | - | - | - | 1,268 | - | - | - | - |
Total revenue | ||||||||
- | - | - | - | 15,216 | 7,812 | - | - | 0 |
Operating expenses: | ||||||||
Cost of goods sold | ||||||||
41,057 | 0 | 0 | - | - | - | - | - | - |
Research and development | ||||||||
55,409 | 49,475 | 49,791 | 62,788 | 62,539 | 41,299 | 16,869 | 16,871 | 15,474 |
Goodwill impairment | ||||||||
25,088 | 0 | 0 | - | - | - | - | - | - |
Selling, general and administrative | ||||||||
133,312 | 63,325 | 19,410 | 14,159 | - | - | - | - | - |
General and administrative | ||||||||
- | - | - | - | 12,077 | 9,433 | 6,068 | 3,707 | 3,198 |
Total operating expenses | ||||||||
254,866 | 112,800 | 69,201 | 76,947 | 74,616 | 50,733 | 22,937 | 20,579 | 18,672 |
Loss from operations | ||||||||
-158,436 | -78,936 | -69,201 | -76,947 | -59,400 | -42,920 | -22,937 | -20,579 | -18,672 |
Other income (expense): | ||||||||
Interest income | ||||||||
730 | 155 | 30 | 31 | 134 | 17 | 107 | 81 | 4 |
Interest expense | ||||||||
43,179 | 3,608 | 3,390 | 3,160 | 2,383 | 2,132 | 1,396 | 722 | 1,495 |
Interest Expense, Debt | ||||||||
0 | 4,016 | 1,016 | - | - | - | - | - | - |
Change in fair value of tranche assets and liabilities | ||||||||
0 | 0 | -1,313 | -2,727 | - | - | - | - | - |
Fair Value Adjustment of Warrants | ||||||||
-33,226 | -335 | -781 | -42 | - | - | - | - | - |
Gain (Loss) on Extinguishment of Debt | ||||||||
-2,595 | -607 | 0 | - | - | - | - | - | - |
Grant income | ||||||||
-5,828 | 0 | 0 | 3,978 | - | - | - | - | - |
Other income and expense | ||||||||
1,904 | 98 | 177 | 107 | - | - | - | - | - |
Gain (Loss) on Contract Termination | ||||||||
5,330 | 0 | 0 | - | - | - | - | - | - |
Business Combination, Bargain Purchase, Gain Recognized, Amount | ||||||||
0 | 27,663 | 0 | - | - | - | - | - | - |
Other income | ||||||||
- | - | - | - | - | - | - | - | 488 |
Other income (expense), net | ||||||||
1,244 | 20,020 | -4,731 | -1,729 | -2,249 | -2,114 | -1,289 | -641 | -1,002 |
Net Income (Loss) Attributable to Parent | ||||||||
-157,192 | -58,916 | -73,932 | -78,676 | -61,649 | -45,034 | -24,226 | -21,220 | - |
Accretion of convertible preferred stock dividends | ||||||||
0 | 19,259 | 21,117 | - | - | - | - | - | - |
Accretion of convertible preferred stock dividends | ||||||||
- | - | - | 16,248 | - | - | - | - | - |
Accretion of redeemable convertible preferred shares | ||||||||
- | - | - | - | - | - | 313 | - | - |
Net loss and comprehensive loss | ||||||||
- | - | - | - | - | - | - | - | -19,674 |
Accretion of redeemable convertible preferred shares | ||||||||
- | - | - | - | - | - | - | 3,763 | 3,238 |
Net loss available to common shareholders | ||||||||
-157,192 | -78,175 | -95,049 | -94,924 | - | - | -24,540 | -24,983 | -22,913 |
Basic and diluted net loss per share (in usd per share) | ||||||||
-17.12 | -109.28 | -20,600.13 | -26,171.49 | -1.81 | -1.53 | -1.23 | -47.53 | -46.60 |
Basic and diluted weighted average shares outstanding (in shares) | ||||||||
9,181 | 715 | 4 | 3 | 34,130 | 29,449 | 19,882 | 525 | 491 |
Product sales, net | ||||||||
Total revenue | ||||||||
46,580 | 0 | 0 | - | - | - | - | - | - |
Contract research | ||||||||
Total revenue | ||||||||
11,677 | 13,959 | 0 | - | - | - | - | - | - |
License | ||||||||
Total revenue | ||||||||
38,173 | 19,905 | 0 | - | - | - | - | - | - |