| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|---|
Revenues: | ||||||||||
License revenue | ||||||||||
- | - | - | - | - | - | 6,000 | - | - | - | - |
Research and development service revenue | ||||||||||
- | - | - | - | - | - | 3 | 802 | - | - | - |
Operating expenses: | ||||||||||
Research, development and patents | ||||||||||
6,079 | 5,625 | 4,223 | 3,519 | 3,017 | 3,259 | 3,365 | 5,013 | 7,784 | 9,710 | 10,873 |
General and administrative | ||||||||||
7,952 | 9,961 | 8,803 | 7,362 | 5,805 | 5,963 | 6,657 | 6,734 | 8,323 | 8,171 | 10,366 |
Total operating expenses | ||||||||||
14,031 | 15,586 | 13,027 | 10,881 | 8,822 | 9,223 | 10,023 | 11,747 | 16,108 | 17,882 | 21,239 |
Operating loss | ||||||||||
-14,031 | -15,586 | -13,027 | -10,881 | -8,822 | -9,223 | -4,020 | -10,945 | -16,108 | -17,882 | -21,239 |
Interest income | ||||||||||
1,148 | 939 | 145 | 66 | 39 | 36 | 20 | 24 | 62 | 438 | 823 |
Other income (expense) | ||||||||||
-46 | -22 | -25 | -47 | 54 | 12 | 24 | 29 | 81 | 176 | 13 |
Impairment charge on investment securities | ||||||||||
- | - | - | - | - | - | - | - | - | -785 | 310 |
Interest expense | ||||||||||
- | - | - | - | 0 | 0 | - | - | 1,595 | 1,768 | 242 |
Loss before income taxes | ||||||||||
-12,928 | -14,669 | -12,907 | -10,862 | -8,837 | -9,199 | -4,024 | -10,950 | -17,722 | -20,174 | -20,361 |
Income tax (expense) | ||||||||||
12 | 5 | -1,744 | 3 | 7 | -3 | 4 | 11 | 11 | 12 | 7 |
Net loss applicable to common stockholders | ||||||||||
-12,941 | -14,675 | -11,163 | -10,865 | -8,845 | -9,195 | - | - | -17,734 | -20,187 | -20,368 |
Net loss applicable to common stockholders | ||||||||||
- | - | - | - | - | - | -4,028 | -10,961 | -17,734 | -20,187 | -20,368 |
Basic and diluted net loss per common share | ||||||||||
-0.30 | -0.36 | -0.32 | -0.33 | -0.33 | -0.38 | -0.19 | -0.66 | -1.20 | -1.63 | -1.68 |
Shares used to compute basic and diluted net loss per common share | ||||||||||
43,158 | 41,124 | 35,137 | 32,986 | 26,578 | 24,067 | 20,697 | 16,522 | 14,813 | 12,410 | 12,105 |
Net loss applicable to common stockholders | ||||||||||
-12,941 | -14,675 | -11,163 | -10,865 | -8,845 | -9,195 | - | - | -17,734 | -20,187 | -20,368 |
Net loss applicable to common stockholders | ||||||||||
- | - | - | - | - | - | -4,028 | -10,961 | -17,734 | -20,187 | -20,368 |
Other comprehensive loss, net of tax: | ||||||||||
Foreign currency translation adjustments | ||||||||||
0 | 1 | 1 | 6 | -1 | -20 | -12 | -11 | -1 | - | - |
Comprehensive loss | ||||||||||
-12,941 | -14,673 | -11,161 | -10,859 | -8,846 | -9,215 | -4,041 | -10,972 | -17,735 | - | - |