| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
Expenses: | ||||||
Research and development | ||||||
42,966 | 28,394 | 12,376 | 22,005 | 18,916 | 8,690 | 4,150 |
General and administrative | ||||||
11,456 | 8,785 | 6,667 | 6,237 | 5,516 | 3,230 | 1,229 |
Loss from operations | ||||||
-54,422 | -37,179 | -19,043 | -28,242 | -24,432 | -11,920 | -5,379 |
Interest income | ||||||
354 | 454 | 324 | 128 | 64 | - | - |
Change in fair value of warrant liability | ||||||
- | - | - | - | - | -1,192 | -153 |
Interest income | ||||||
- | - | - | - | - | 12 | 47 |
Interest expense | ||||||
- | - | 159 | 464 | 475 | 117 | 91 |
Other expense | ||||||
-53 | -1 | -20 | -65 | -7 | - | - |
Net loss | ||||||
-54,121 | -36,726 | -18,898 | -28,643 | -24,850 | -10,833 | -5,270 |
Cumulative preferred stock dividends | ||||||
- | - | - | - | - | 2,545 | 3,804 |
Net loss applicable to common shareholders | ||||||
- | - | - | - | - | -13,378 | -9,074 |
Per share information: | ||||||
Net loss per share of common stock—basic and diluted | ||||||
-0.99 | -0.90 | -0.80 | -1.47 | -1.67 | -2.17 | -19.60 |
Basic and diluted weighted average shares outstanding | ||||||
54,512 | 40,895 | 23,540 | 19,498 | 14,919 | 6,152 | 462 |
Net loss | ||||||
-54,121 | -36,726 | -18,898 | -28,643 | -24,850 | - | - |
Other comprehensive income (loss): | ||||||
Unrealized gain on available-for-sale securities | ||||||
- | 94 | -96 | - | - | - | - |
Total comprehensive loss | ||||||
-54,121 | -36,632 | -18,994 | -28,643 | -24,850 | - | - |