| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 | Dec'13 | Sep'13 | Jun'13 | Mar'13 | Sep'12 | Jun'12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenue | ||||||||||||||||||||||||||||||
License and collaboration revenues | ||||||||||||||||||||||||||||||
267 | - | 988 | 577 | 1,244 | - | 0 | 0 | - | - | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Total revenue | ||||||||||||||||||||||||||||||
267 | 526 | 988 | 577 | 1,244 | 3,459 | 0 | 0 | 9,467 | - | - | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Operating expenses | ||||||||||||||||||||||||||||||
Research and Development Expense | ||||||||||||||||||||||||||||||
71,708 | 62,940 | 47,362 | 38,324 | 34,240 | 26,758 | 23,626 | 23,829 | 19,659 | 15,244 | 13,482 | 14,962 | 14,397 | 15,952 | 16,106 | 18,441 | 17,988 | 14,913 | 14,563 | 11,276 | 8,207 | 7,076 | 6,886 | 7,149 | 4,960 | 4,320 | 5,492 | 4,510 | 5,475 | 4,249 | 3,652 |
General and administrative | ||||||||||||||||||||||||||||||
18,046 | 12,232 | 10,685 | 9,894 | 9,762 | 6,373 | 5,313 | 4,841 | 5,154 | 2,984 | 3,119 | 3,654 | 3,693 | 3,901 | 3,475 | 3,786 | 4,130 | 3,575 | 4,161 | 4,240 | 3,779 | 3,366 | 3,662 | 2,986 | 2,685 | 2,554 | 3,717 | 2,382 | 2,524 | 1,717 | 1,082 |
Restructuring costs | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 334 | 1,025 | 0 | 0 | 0 | - | - |
Total operating expenses | ||||||||||||||||||||||||||||||
89,754 | 75,172 | 58,047 | 48,218 | 44,002 | 33,131 | 28,939 | 28,670 | 24,813 | 18,228 | 16,601 | 18,616 | 18,090 | 19,853 | 19,581 | 22,227 | 22,118 | 18,488 | 18,724 | 15,516 | 11,986 | 10,442 | 10,548 | 10,135 | 7,979 | 7,899 | 9,209 | 6,892 | 7,999 | 5,966 | 4,734 |
Loss from operations | ||||||||||||||||||||||||||||||
-89,487 | -74,646 | -57,059 | -47,641 | -42,758 | -29,672 | -28,939 | -28,670 | -15,346 | -18,228 | -16,601 | -18,616 | -18,090 | -19,853 | -19,581 | -22,227 | -22,118 | -18,488 | -18,724 | -15,516 | -11,986 | -10,442 | -10,548 | -10,135 | -7,979 | -7,899 | -9,209 | -6,892 | -7,999 | -5,966 | -4,734 |
Other income, net | ||||||||||||||||||||||||||||||
2,832 | 2,270 | 2,786 | 1,946 | 1,846 | 1,400 | 1,371 | 801 | 637 | 333 | 251 | 277 | 244 | 131 | 160 | 166 | 204 | 71 | -17 | 70 | 46 | 28 | 24 | 73 | -202 | -282 | 462 | -694 | -570 | 34 | 70 |
Change in fair value of warrant liability | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -27 | -1,907 | 976 | 5,475 | 3,189 | 20,596 | 385 | -4,371 | - | - |
Loss before income taxes | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -11,370 | -29,343 | -7,971 | -4,198 | -5,932 | -4,664 |
Income tax benefit | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -138 | 55 | 41 | 19 | 14 | 13 |
Net Income (Loss) Attributable to Parent | ||||||||||||||||||||||||||||||
-86,655 | -72,376 | -54,273 | -45,695 | -40,912 | -28,272 | -27,568 | -27,869 | -14,709 | -17,895 | -16,350 | -18,339 | -17,846 | -19,722 | -19,421 | -22,061 | -21,914 | -18,417 | -18,741 | -15,446 | -11,940 | -10,387 | -8,617 | -11,038 | -13,656 | -11,232 | -29,398 | -8,012 | -4,217 | -5,946 | -4,677 |
Other Comprehensive Income (Loss), Securities, Available-for-Sale, Unrealized Holding Gain (Loss) Arising During Period, after Tax | ||||||||||||||||||||||||||||||
-182 | -2 | 103 | 151 | 158 | 35 | 99 | 154 | -288 | -34 | 13 | -104 | 71 | -51 | -34 | 33 | 27 | 35 | 6 | -9 | 5 | -8 | -12 | 24 | 10 | -13 | 0 | 0 | 0 | - | - |
Comprehensive loss | ||||||||||||||||||||||||||||||
-86,837 | -72,378 | -54,170 | -45,544 | -40,754 | -28,237 | -27,469 | -27,715 | -14,997 | -17,929 | -16,337 | -18,443 | -17,775 | -19,773 | -19,455 | -22,028 | -21,887 | -18,382 | -18,735 | -15,455 | -11,935 | -10,395 | -8,629 | -11,014 | -13,646 | -11,245 | -29,398 | -8,012 | -4,217 | - | - |
Basic and diluted net loss per share (USD per share) | ||||||||||||||||||||||||||||||
-2.02 | -1.88 | -1.38 | -1.26 | -1.17 | -0.89 | -0.85 | -0.94 | -0.51 | -0.66 | -0.65 | -0.74 | -0.73 | -0.99 | -0.97 | -1.11 | -1.13 | - | -1.11 | -0.95 | -0.77 | - | - | -0.82 | -1.01 | - | - | -0.80 | - | -0.93 | -0.73 |
Loss per share, basic (in US$ per share) | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -0.64 | - | - | - | -2.95 | - | -0.42 | - | - |
Diluted net loss per share | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -0.72 | - | - | - | -2.95 | - | -0.68 | - | - |
Weighted average number of shares used in computing net loss per share, basic and diluted (shares) | ||||||||||||||||||||||||||||||
42,886 | 39,518 | 39,197 | 36,173 | 34,980 | 32,578 | 32,410 | 29,757 | 28,843 | 26,856 | 24,970 | 24,950 | 24,383 | 19,931 | 19,924 | 19,912 | 19,380 | 19,076 | 16,841 | 16,235 | 15,453 | - | - | 13,498 | 13,457 | - | - | 9,957 | - | 6,361 | 6,358 |
Weighted average number of shares used in computing net loss per share, basic | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 13,527 | - | - | - | 9,957 | - | 9,957 | - | - |
Weighted average number of shares used in computing net loss per share, diluted | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 14,717 | - | - | - | 9,957 | - | 10,078 | - | - |