| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 | Dec'13 | Sep'13 | Jun'13 | Mar'13 | Sep'12 | Jun'12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenue: | ||||||||||||||||||||||||||||||
Revenue | ||||||||||||||||||||||||||||||
124,485 | 125,568 | 118,669 | 116,681 | 111,335 | 106,732 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Revenues | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | 119,927 | 114,905 | 104,903 | 101,820 | 89,855 | 86,489 | 83,572 | 75,332 | 65,771 | 62,667 | 55,970 | 52,620 | 50,435 | 47,593 | 42,095 | 38,141 | 34,478 | 31,403 | 27,318 | 24,872 | 0 | 0 | 0 |
Costs and expenses: | ||||||||||||||||||||||||||||||
Cost of product and service revenue | ||||||||||||||||||||||||||||||
46,347 | 44,039 | 40,032 | 38,398 | 37,345 | 36,331 | 34,726 | 32,740 | 32,412 | 31,880 | 31,121 | 31,891 | 31,538 | 30,245 | 30,442 | 28,656 | 26,656 | 26,126 | 24,193 | 23,175 | 22,164 | 21,149 | 19,277 | 17,790 | 16,452 | 15,009 | 13,274 | 12,824 | 0 | 0 | 0 |
Research and development | ||||||||||||||||||||||||||||||
69,510 | 68,035 | 66,594 | 66,238 | 63,794 | 61,599 | 58,743 | 53,466 | 49,919 | 46,888 | 43,209 | 40,552 | 38,313 | 34,720 | 31,795 | 28,890 | 25,889 | 24,597 | 22,963 | 23,112 | 22,588 | 21,404 | 20,477 | 18,300 | 16,652 | 14,979 | 13,554 | 12,741 | 0 | 0 | 0 |
Selling, general and administrative | ||||||||||||||||||||||||||||||
98,480 | 96,195 | 89,616 | 84,044 | 82,194 | 78,195 | 77,641 | 78,211 | 76,206 | 74,334 | 71,271 | 68,498 | 65,361 | 62,700 | 60,220 | 56,649 | 53,965 | 53,186 | 53,978 | 54,457 | 54,514 | 51,063 | 45,159 | 40,632 | 34,460 | 29,912 | 24,992 | 20,255 | 0 | 0 | 0 |
Total costs and expenses | ||||||||||||||||||||||||||||||
214,337 | 208,269 | 196,242 | 188,680 | 183,333 | 176,125 | 171,110 | 164,417 | 158,537 | 153,102 | 145,601 | 140,941 | 135,212 | 127,665 | 122,457 | 114,195 | 106,510 | 103,909 | 101,134 | 100,744 | 99,266 | 93,616 | 84,913 | 76,722 | 67,564 | 59,900 | 51,820 | 45,820 | 0 | 0 | 0 |
Loss from operations | ||||||||||||||||||||||||||||||
-89,852 | -82,701 | -77,573 | -71,999 | -71,998 | -69,393 | -59,176 | -54,083 | -38,610 | -38,197 | -40,698 | -39,121 | -45,357 | -41,176 | -38,885 | -38,863 | -40,739 | -41,242 | -45,164 | -48,124 | -48,831 | -46,023 | -42,818 | -38,581 | -33,086 | -28,497 | -24,502 | -20,948 | 0 | 0 | 0 |
Other income (expense): | ||||||||||||||||||||||||||||||
Interest income | ||||||||||||||||||||||||||||||
3,000 | 2,819 | 2,619 | 2,240 | 1,616 | 1,331 | 1,086 | 954 | 900 | 809 | 673 | 525 | 469 | 390 | 318 | 272 | 234 | 233 | 249 | 256 | 275 | 272 | 244 | 201 | 129 | 68 | 32 | 16 | 0 | 0 | 0 |
Interest expense | ||||||||||||||||||||||||||||||
9,622 | 8,487 | 8,685 | 7,901 | 7,616 | 7,431 | 6,366 | 6,291 | 6,215 | 6,153 | 6,107 | 6,060 | 5,858 | 5,672 | 5,160 | 4,673 | 4,348 | 4,017 | 3,899 | 3,574 | 4,588 | 4,140 | 3,778 | 3,619 | 2,093 | 1,942 | 1,631 | 1,313 | 0 | 0 | 0 |
Other expense, net | ||||||||||||||||||||||||||||||
-2,426 | -929 | -1,880 | -1,604 | -1,833 | -1,658 | -332 | -298 | 235 | 183 | -92 | -259 | -431 | -515 | -346 | -226 | -271 | -389 | -331 | -384 | -366 | -147 | -133 | -38 | -32 | -66 | -228 | -26 | 0 | 0 | 0 |
Loss on extinguishment of debt and termination of revolving loan facility | ||||||||||||||||||||||||||||||
0 | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Revaluation of preferred stock warrant liability | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -1,156 | 1,209 | 1,280 | 0 | 0 | 0 |
Total other expense, net | ||||||||||||||||||||||||||||||
32,680 | 42,274 | -7,946 | -7,265 | -7,833 | -7,758 | -5,612 | -5,635 | -5,080 | -5,161 | -5,526 | -5,794 | -5,820 | -5,797 | -5,188 | -4,627 | -4,385 | -4,173 | -3,981 | -3,702 | -4,679 | -4,015 | -3,667 | -3,456 | -358 | -784 | -618 | -43 | 0 | 0 | 0 |
Net loss before provision for income tax | ||||||||||||||||||||||||||||||
-57,172 | -40,427 | -85,519 | -79,264 | -79,831 | -77,151 | -64,788 | -59,718 | -43,690 | -43,358 | -46,224 | -44,915 | -51,177 | -46,973 | -44,073 | -43,490 | -45,124 | -45,415 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - |
Provision for income tax | ||||||||||||||||||||||||||||||
250 | 269 | 275 | 268 | 265 | 249 | 252 | 240 | 222 | 204 | 180 | 173 | 161 | 116 | 239 | 201 | 166 | 166 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - |
Net Income (Loss) Attributable to Parent | ||||||||||||||||||||||||||||||
-57,422 | -40,696 | -85,794 | -79,532 | -80,096 | -77,400 | -65,040 | -59,958 | -43,912 | -43,562 | -46,404 | -45,088 | -51,338 | -47,089 | -44,312 | -43,691 | -45,290 | -45,581 | -49,145 | -51,826 | -53,510 | -50,038 | -46,485 | -42,037 | -33,444 | -29,281 | -25,120 | -20,991 | 0 | 0 | 0 |
Accretion of mandatorily redeemable convertible preferred stock | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 4,653 | 6,531 | 8,375 | 0 | 0 | 0 |
Net loss attributable to common stockholders | ||||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -33,934 | -31,651 | -29,366 | 0 | 0 | 0 |
Net loss per share - basic and diluted (in dollars per share) | ||||||||||||||||||||||||||||||
-1.04 | 0.72 | -0.64 | -0.57 | -0.69 | -0.67 | -0.56 | -0.80 | -0.75 | -0.32 | -0.45 | -0.20 | -0.87 | -0.54 | -0.51 | -0.55 | -0.74 | -0.44 | -0.49 | -0.66 | -0.81 | -0.67 | -0.67 | -0.78 | -0.68 | 27.66 | -0.53 | -13.69 | -17.88 | -18.28 | -16.02 |
Weighted average shares used in computing basic and diluted net loss per share (in shares) | ||||||||||||||||||||||||||||||
36,999 | 36,033 | 35,576 | 35,174 | 31,569 | 30,930 | 29,366 | 25,757 | 25,479 | 25,424 | 25,240 | 22,672 | 21,588 | 21,128 | 19,864 | 19,803 | 19,669 | 19,536 | 19,431 | 18,831 | 18,310 | 18,236 | 18,134 | 18,069 | 16,917 | 14,849 | 14,616 | 570 | 537 | 358 | 338 |
Total product and service revenue | ||||||||||||||||||||||||||||||
Revenue | ||||||||||||||||||||||||||||||
0 | - | 0 | 0 | 0 | - | 0 | 0 | 0 | - | 71,333 | 73,585 | 72,763 | - | 68,190 | 62,933 | 57,943 | 56,639 | 51,459 | 48,813 | 46,578 | 44,497 | 38,667 | 34,621 | 0 | - | 0 | 0 | - | - | - |
Collaboration revenue | ||||||||||||||||||||||||||||||
Revenue | ||||||||||||||||||||||||||||||
0 | - | 0 | 0 | 0 | - | 0 | 0 | 0 | - | 33,570 | 28,235 | 17,092 | - | 15,382 | 12,399 | 7,828 | 6,028 | 4,511 | 3,807 | 3,857 | 3,096 | 1,697 | 618 | 0 | - | 0 | 0 | - | - | - |