| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
Operating activities: | ||||||
Net loss | ||||||
-23,676 | -37,380 | -34,765 | -20,467 | -15,557 | -9,890 | |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Depreciation | ||||||
479 | 581 | 330 | - | - | - | |
Depreciation, Depletion and Amortization, Nonproduction | ||||||
- | - | - | 192 | 167 | 166 | |
Stock-based compensation | ||||||
2,983 | 4,693 | 3,241 | 563 | 207 | 185 | |
Amortization of right-of-use asset | ||||||
415 | 0 | - | - | - | - | |
Fair value of stock issued for legal settlements | ||||||
- | - | 1,606 | 0 | 0 | - | |
Loss on disposal of fixed assets | ||||||
-128 | -107 | 0 | -13 | -19 | -5 | |
Change in fair value of warrant liability | ||||||
- | - | - | 466 | 34 | -167 | |
Accretion of investment discount, net | ||||||
2 | 50 | -18 | -125 | -260 | -64 | |
Amortization of debt discount | ||||||
70 | 37 | 42 | 70 | 79 | 41 | |
Change in operating assets and liabilities: | ||||||
Accounts receivable, net | ||||||
-585 | -3,353 | 4,223 | 0 | -96 | -83 | |
Accounts receivable from related party | ||||||
- | - | -515 | -121 | 481 | -4 | |
Inventory | ||||||
-12 | 162 | 591 | 464 | -77 | 166 | |
Other current assets | ||||||
-411 | -98 | 470 | 985 | -27 | 109 | |
Accounts payable | ||||||
-543 | 70 | 624 | 46 | 370 | - | |
Accounts payable and accrued expenses | ||||||
- | - | - | - | - | -33 | |
Accrued compensation | ||||||
-2,985 | -689 | 1,997 | 1,247 | 1,018 | 33 | |
Deferred revenue | ||||||
72 | -158 | 389 | 121 | 0 | - | |
Accrued clinical expenses | ||||||
- | - | - | - | - | -129 | |
Lease liabilities, net | ||||||
-364 | 0 | - | - | - | - | |
Other current and long-term liabilities | ||||||
-451 | 68 | 663 | -416 | 1,009 | - | |
Other current and long-term liabilities | ||||||
- | - | - | - | - | 6 | |
Customer deposit from related party | ||||||
- | - | - | 0 | 1,283 | 0 | |
Net cash used in operating activities | ||||||
-22,866 | -29,432 | -30,624 | -19,368 | -11,392 | -9,907 | |
Purchases of short-term investments | ||||||
0 | 9,102 | 94,613 | 18,897 | 18,590 | 12,400 | |
Maturities of short-term investments | ||||||
2,550 | 29,901 | 73,800 | 25,450 | 21,500 | 4,250 | |
Sales of short-term investments | ||||||
- | - | - | - | - | 500 | |
Purchases of property and equipment | ||||||
194 | 1,282 | 1,043 | 352 | 139 | 268 | |
Proceeds from disposal of property and equipment | ||||||
- | - | - | 0 | 6 | 0 | |
Net cash provided by investing activities | ||||||
2,356 | 19,517 | -21,856 | 6,201 | 2,777 | -7,918 | |
Financing activities: | ||||||
Proceeds from issuance of common stock and warrants, net of issuance costs | ||||||
23,377 | 9,823 | 0 | - | - | - | |
Issuance of preferred stock for cash, net of offering costs | ||||||
- | - | - | 14,517 | 0 | 13,622 | |
Issuance of preferred stock to related party for cash | ||||||
- | - | - | - | - | 6,600 | |
Proceeds from initial public offering, net of issuance costs | ||||||
- | - | - | 67,233 | 0 | 0 | |
Proceeds from long-term loan, net of issuance costs | ||||||
10,000 | 0 | - | 0 | 5,000 | 4,958 | |
Fees paid in connection with fifth amendment to loan and security agreement | ||||||
0 | 30 | 0 | 30 | 0 | 0 | |
Repayments of Long-term Debt | ||||||
20,000 | 0 | - | - | - | 3,000 | |
Proceeds from common stock issued under employee stock purchase plan | ||||||
0 | 148 | 429 | 0 | 0 | - | |
Proceeds from sale of common stock upon exercise of stock options | ||||||
1 | 53 | 184 | 1,066 | 62 | 8 | |
Net cash provided by financing activities | ||||||
13,378 | 9,994 | 613 | 82,786 | 5,062 | 22,188 | |
Net (decrease) increase in cash and cash equivalents | ||||||
-7,132 | 79 | - | - | - | - | |
Effect of exchange rate changes on cash and cash equivalents | ||||||
- | - | - | 0 | 7 | 12 | |
Net increase (decrease) in cash and cash equivalents | ||||||
- | - | -51,867 | 69,619 | -3,546 | 4,375 | |
Supplemental cash flow information: | ||||||
Interest paid | ||||||
719 | 642 | 562 | - | - | - | |
Interest paid | ||||||
- | - | - | 527 | 475 | 164 | |
Income taxes paid | ||||||
0 | 7 | 2 | 0 | 2 | 1 | |
Conversion of customer deposit from related party to preferred stock | ||||||
- | - | - | 1,283 | 0 | 0 | |
Property and equipment in accounts payable | ||||||
32 | 201 | 83 | 140 | 0 | 0 | |
Unpaid issuance costs | ||||||
0 | 250 | 0 | - | - | - | |
Conversion of convertible preferred stock to common stock | ||||||
- | - | - | 70,498 | 0 | 0 | |
Fair value of commitment shares issued | ||||||
0 | 595 | 0 | 591 | 0 | 0 | |