| Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Operating activities: | |||||||||||||||
Net loss | |||||||||||||||
-4,913 | -3,706 | -6,767 | -8,290 | -8,756 | -6,745 | -9,753 | -12,126 | -10,120 | -9,170 | -7,730 | -7,745 | -7,495 | -5,260 | -4,131 | -3,581 |
Adjustments to reconcile net loss to net cash used in operating activities: | |||||||||||||||
Depreciation, Depletion and Amortization, Nonproduction | |||||||||||||||
- | 61 | 150 | 150 | - | 124 | 147 | 129 | - | 85 | 70 | 66 | 50 | 52 | 45 | 45 |
Stock-based compensation | |||||||||||||||
683 | 659 | 536 | 1,105 | 1,083 | 1,007 | 1,214 | 1,389 | 1,139 | 1,023 | 616 | 463 | 363 | 55 | 95 | 50 |
Amortization of right-of-use asset | |||||||||||||||
114 | 115 | 94 | 92 | - | - | - | - | - | - | - | - | - | - | - | - |
Loss on disposal of fixed assets | |||||||||||||||
0 | -33 | -95 | 0 | 0 | 0 | 0 | -107 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -13 |
Change in fair value of warrant liability | |||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | -84 | 669 | -96 | -23 |
Accretion of investment discount, net | |||||||||||||||
0 | 0 | 0 | 2 | 30 | 13 | 2 | 5 | 6 | -13 | -8 | -3 | -29 | -41 | -30 | -25 |
Amortization of debt discount | |||||||||||||||
0 | 0 | 48 | 22 | 8 | 7 | 11 | 11 | 11 | 11 | 10 | 10 | 10 | 17 | 22 | 21 |
Change in operating assets and liabilities: | |||||||||||||||
Accounts receivable, net | |||||||||||||||
47 | -209 | -1,382 | 959 | -1,905 | -274 | 496 | -1,670 | 1,708 | 758 | 722 | 1,035 | 0 | 0 | 0 | 0 |
Accounts receivable from related party | |||||||||||||||
- | - | - | - | - | - | - | - | 0 | 0 | 0 | -515 | 0 | -70 | -309 | 258 |
Inventory | |||||||||||||||
-129 | -40 | 259 | -102 | -375 | 113 | -25 | 449 | 507 | 164 | -181 | 101 | 389 | -39 | -77 | 191 |
Other current assets | |||||||||||||||
1,193 | 156 | -837 | -923 | 707 | 52 | -330 | -527 | 710 | 299 | -299 | -240 | -1,612 | 2,643 | -60 | 14 |
Accounts payable | |||||||||||||||
181 | -533 | -54 | -137 | -65 | -140 | -799 | 1,074 | 90 | 476 | -159 | 217 | - | - | - | - |
Accounts payable and accrued expenses | |||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 459 | -114 | 174 |
Accrued compensation | |||||||||||||||
112 | -385 | 107 | -2,819 | 1,134 | 539 | 301 | -2,663 | 1,823 | 290 | 826 | -942 | 1,813 | 448 | -14 | -1,000 |
Deferred revenue | |||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | 50 | 121 | 0 | 0 | 0 |
Accrued clinical expenses | |||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | -473 | -60 | -241 |
Deferred revenue | |||||||||||||||
- | -37 | -50 | 18 | - | -1 | -35 | -173 | - | - | - | - | - | - | - | - |
Lease liabilities, net | |||||||||||||||
-116 | -112 | -94 | -42 | - | - | - | - | - | - | - | - | - | - | - | - |
Other current and long-term liabilities | |||||||||||||||
- | -221 | -337 | 195 | - | -208 | 935 | -93 | - | 180 | 420 | -94 | - | 1,596 | 96 | -2 |
Net cash used in operating activities | |||||||||||||||
-4,879 | -3,989 | -4,356 | -9,642 | -5,415 | -5,293 | -8,122 | -10,602 | -9,197 | -7,019 | -6,055 | -8,353 | -5,775 | -4,930 | -3,681 | -4,982 |
Purchases of short-term investments | |||||||||||||||
- | - | - | - | - | - | - | - | 14,296 | 15,389 | 39,899 | 25,029 | 0 | 3,918 | 12,971 | 2,008 |
Maturities of short-term investments | |||||||||||||||
0 | 0 | 0 | 2,550 | 5,599 | 1,001 | -1 | 23,302 | 32,300 | 29,000 | 10,000 | 2,500 | 9,300 | 6,000 | 4,350 | 5,800 |
Purchases of property and equipment | |||||||||||||||
150 | 24 | 1 | 19 | 415 | 210 | 299 | 358 | 139 | 345 | 178 | 381 | 93 | 196 | 18 | 45 |
Net cash provided by investing activities | |||||||||||||||
-150 | -24 | -1 | 2,531 | 5,185 | -7,317 | -1,295 | 22,944 | 17,865 | 13,266 | -30,077 | -22,910 | 9,207 | 1,886 | -8,639 | 3,747 |
Financing activities: | |||||||||||||||
Proceeds from issuance of common stock and warrants, net of issuance costs | |||||||||||||||
14,718 | -134 | 8,186 | 607 | -150 | 9,973 | 0 | 0 | - | - | - | - | - | - | - | - |
Proceeds from long-term loan, net of issuance costs | |||||||||||||||
0 | 0 | 0 | 10,000 | 0 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Proceeds from sale of common stock upon exercise of stock options | |||||||||||||||
0 | 0 | 0 | 1 | 15 | 7 | 3 | 28 | 138 | 9 | 37 | 0 | 1 | 1,054 | 9 | 2 |
Net cash provided by financing activities | |||||||||||||||
-296 | 9,880 | -6,814 | 10,608 | -135 | 9,950 | 151 | 28 | 357 | 9 | 247 | 0 | 67,219 | 1,039 | 14,526 | 2 |
Net (decrease) increase in cash and cash equivalents | |||||||||||||||
-5,325 | 5,867 | -11,171 | 3,497 | -365 | -2,660 | -9,266 | 12,370 | - | - | - | - | - | - | - | - |
Net increase (decrease) in cash and cash equivalents | |||||||||||||||
- | - | - | - | - | - | - | - | 9,025 | 6,256 | -35,885 | -31,263 | 70,651 | -2,005 | 2,206 | -1,233 |
Supplemental cash flow information: | |||||||||||||||
Interest paid | |||||||||||||||
19 | 137 | 358 | 205 | 169 | 166 | 158 | 149 | - | - | - | - | - | - | - | - |
Interest paid | |||||||||||||||
- | - | - | - | - | - | - | - | - | - | 140 | 130 | 122 | 139 | 134 | 132 |
Property and equipment in accounts payable | |||||||||||||||
32 | 0 | -4 | 4 | 95 | 0 | 60 | 46 | -43 | 30 | -33 | 129 | 140 | -121 | 121 | 0 |
Unpaid issuance costs | |||||||||||||||
-295 | -82 | 351 | 26 | 90 | 160 | 0 | 0 | - | - | - | - | - | - | - | - |