| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|---|
Revenues: | ||||||||||
Collaborative licensing and milestone revenue | ||||||||||
0 | 3,000 | 387 | 3,426 | 1,426 | 1,287 | 972 | 18,390 | 5,074 | 3,217 | 4,638 |
Total revenues | ||||||||||
421,026 | 337,277 | 286,630 | 276,371 | 248,997 | 197,668 | 85,551 | 39,084 | 15,689 | 14,562 | 15,006 |
Operating expenses: | ||||||||||
Cost of goods sold | ||||||||||
106,712 | 86,845 | 87,915 | 110,104 | 71,837 | 77,440 | 54,772 | 32,139 | 16,739 | 12,276 | 12,301 |
Research and development | ||||||||||
72,119 | 55,688 | 57,290 | 45,678 | 28,662 | 18,731 | 21,560 | 9,937 | 14,873 | 18,628 | 26,233 |
Selling, general and administrative | ||||||||||
200,782 | 177,265 | 161,494 | 152,613 | 139,043 | 106,662 | 62,508 | 46,306 | 20,159 | 6,367 | 5,020 |
Amortization of acquired intangible assets | ||||||||||
5,700 | 0 | 0 | - | - | - | - | - | - | - | - |
Acquisition-related charges, product discontinuation and other | ||||||||||
25,230 | 1,564 | 4,868 | 0 | 0 | - | - | - | - | - | - |
Impairment of long-lived assets | ||||||||||
- | - | - | - | - | - | - | - | 3,019 | - | - |
Total operating expenses | ||||||||||
410,546 | 321,362 | 311,567 | 308,395 | 239,542 | 202,833 | 138,840 | 88,382 | 54,790 | 37,271 | 43,554 |
Income from operations | ||||||||||
10,480 | 15,915 | -24,937 | -32,024 | 9,455 | -5,165 | -53,289 | -49,298 | -39,101 | -22,709 | -28,548 |
Other (expense) income: | ||||||||||
Interest income | ||||||||||
7,376 | 6,497 | 4,078 | 1,323 | 678 | 382 | 259 | 275 | 255 | 146 | 77 |
Interest expense | ||||||||||
23,628 | 21,949 | 18,047 | 7,061 | 7,725 | 8,278 | 7,253 | 1,807 | 4,780 | 3,959 | 1,723 |
Loss on early extinguishment of debt | ||||||||||
0 | - | -3,732 | 0 | -52 | - | -3,398 | -1,062 | 0 | -184 | - |
Royalty interest obligation | ||||||||||
- | - | - | - | 71 | 323 | 623 | 278 | -227 | 930 | 1,880 |
Other, net | ||||||||||
-4,976 | -888 | 167 | -82 | -165 | -159 | -47 | -111 | 71 | 487 | 367 |
Total other expense, net | ||||||||||
-21,228 | -16,340 | -17,534 | -5,820 | -7,335 | -8,378 | -11,062 | -2,983 | -4,227 | -4,440 | -3,159 |
Income (loss) before income taxes | ||||||||||
-10,748 | -425 | -42,471 | -37,844 | 2,120 | -13,543 | -64,351 | -52,281 | -43,328 | - | - |
Income tax expense | ||||||||||
268 | 46 | 140 | 105 | 264 | 173 | -442 | 0 | 0 | - | - |
Net income (loss) | ||||||||||
-11,016 | -471 | -42,611 | -37,949 | 1,856 | -13,716 | -63,909 | -52,281 | -43,328 | -27,149 | -31,707 |
Net income (loss) per share: | ||||||||||
Basic and diluted net income (loss) per common share (in USD per share) | ||||||||||
-0.27 | -0.01 | -1.07 | -1.02 | - | - | - | -1.72 | -2.64 | -47.29 | -55.32 |
Basic net income (loss) per common share (in USD per share) | ||||||||||
- | - | - | - | 0.05 | -0.39 | -1.93 | - | - | - | - |
Diluted net income (loss per common share (in USD per share) | ||||||||||
- | - | - | - | 0.04 | -0.39 | -1.93 | - | - | - | - |
Weighted average common shares outstanding: | ||||||||||
Basic and diluted (in shares) | ||||||||||
41,513 | 40,911 | 39,806 | 37,236 | 36,540 | 35,299 | 33,182 | 30,332 | 16,437 | 574 | 573 |
Diluted (in shares) | ||||||||||
- | - | - | - | 41,301 | 35,299 | 33,182 | - | - | - | 573 |
Product | ||||||||||
Total revenues | ||||||||||
418,926 | 332,427 | 284,342 | 270,073 | 244,487 | 193,526 | 81,956 | 18,191 | 6,895 | 7,640 | 10,368 |
Royalty | ||||||||||
Total revenues | ||||||||||
2,100 | 1,850 | 1,901 | 2,872 | 3,084 | 2,855 | 2,623 | 2,503 | 3,720 | 3,705 | - |