| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
License and collaboration revenue - related party | ||||||
231 | 30,925 | 20,063 | - | - | - | |
Operating expenses: | ||||||
Research and development | ||||||
65,003 | 59,497 | 46,181 | 25,705 | 11,831 | 7,459 | |
General and administrative | ||||||
15,749 | 13,697 | 11,779 | 6,961 | 2,963 | 1,860 | |
Total operating expenses | ||||||
80,752 | 73,194 | 57,960 | 32,666 | 14,794 | 9,319 | |
Loss from operations | ||||||
-80,521 | -42,269 | -37,897 | -32,666 | -14,794 | -9,319 | |
Interest income | ||||||
2,813 | 2,566 | 948 | 242 | 19 | 16 | |
Interest expense | ||||||
169 | - | - | - | - | - | |
Change in fair value of redeemable convertible preferred stock tranche and warrant liabilities | ||||||
- | - | - | 4,719 | 83 | 1,769 | |
Other expense, net | ||||||
-1 | -20 | -8 | -34 | - | - | |
Loss before income tax expense | ||||||
-77,878 | -39,723 | -36,957 | -37,177 | - | - | |
Income tax expense | ||||||
-700 | -799 | - | - | - | - | |
Net loss | ||||||
-77,187 | -38,924 | -36,957 | -37,177 | -14,858 | -11,072 | |
Net loss attributable to common stockholders | ||||||
- | - | - | -37,735 | -14,933 | -11,218 | |
Net loss per share, basic and diluted | ||||||
-2.98 | -1.74 | -2.09 | -5.80 | -59.32 | -49.38 | |
Weighted-average shares used to compute net loss per share, basic and diluted | ||||||
25,894 | 22,364 | 17,694 | 6,501 | 251 | 227 | |