| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Sep'15 | Jun'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
License and collaboration revenue - related party | ||||||||||||||||||
2,318 | 231 | 3,629 | 11,162 | 0 | - | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - |
License and collaboration revenue - related party | ||||||||||||||||||
- | - | - | - | - | - | - | - | 0 | - | 0 | - | - | - | - | - | - | - | - |
License and collaboration revenue - related party | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | - | - | - | - |
Operating expenses: | ||||||||||||||||||
Research and development | ||||||||||||||||||
71,327 | 65,003 | 63,341 | 58,193 | 56,573 | 59,497 | 56,972 | 55,995 | 50,267 | 46,181 | 43,280 | 37,673 | 31,362 | 25,705 | 20,040 | 16,776 | 0 | 0 | 0 |
General and administrative | ||||||||||||||||||
16,561 | 15,749 | 15,158 | 14,504 | 13,819 | 13,697 | 13,252 | 12,484 | 12,430 | 11,779 | 11,282 | 10,266 | 8,537 | 6,961 | 5,250 | 4,459 | 0 | 0 | 0 |
Total operating expenses | ||||||||||||||||||
87,888 | 80,752 | 78,499 | 72,697 | 70,392 | 73,194 | 70,224 | 68,479 | 62,697 | 57,960 | 54,562 | 47,939 | 39,899 | 32,666 | 25,290 | 21,235 | 0 | 0 | 0 |
Loss from operations | ||||||||||||||||||
-85,570 | -80,521 | -78,634 | -70,856 | -48,688 | -42,269 | -30,370 | -25,961 | -31,853 | -37,897 | -45,781 | -47,939 | -39,899 | -32,666 | -25,290 | -21,235 | 0 | 0 | 0 |
Interest income | ||||||||||||||||||
2,608 | 2,813 | 2,759 | 2,757 | 2,729 | 2,566 | 2,267 | 1,768 | 1,344 | 948 | 628 | 527 | 402 | 242 | 94 | 0 | 0 | 0 | - |
Interest expense | ||||||||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Change in fair value of redeemable convertible preferred stock tranche and warrant liabilities | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 4,719 | 4,148 | 4,284 | 0 | 0 | 0 |
Other expense, net | ||||||||||||||||||
0 | - | - | - | 0 | - | - | - | - | - | - | - | - | - | 0 | 0 | - | - | - |
Loss before income tax expense | ||||||||||||||||||
-83,862 | -77,878 | -75,898 | -68,122 | -45,982 | -39,723 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - |
Income tax expense | ||||||||||||||||||
-707 | -700 | -2,347 | -2,245 | -616 | -799 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - |
Net loss | ||||||||||||||||||
-83,164 | -77,187 | -73,551 | -65,877 | -45,366 | -38,924 | -28,111 | -24,201 | -30,517 | -36,957 | -45,153 | -47,412 | -39,531 | -37,177 | -29,378 | -25,513 | 0 | 0 | 0 |
Net loss attributable to common stockholders | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | -37,735 | -29,972 | -25,814 | 0 | 0 | 0 |
Net loss per share, basic and diluted | ||||||||||||||||||
-0.72 | -0.61 | -0.61 | -1.18 | -0.58 | -0.59 | -0.38 | -0.41 | -0.36 | -0.07 | -0.29 | -0.89 | -0.84 | 55.10 | -0.87 | -19.07 | -40.96 | -12.79 | -13.78 |
Weighted-average shares used to compute net loss per share, basic and diluted | ||||||||||||||||||
27,703 | 27,658 | 26,956 | 24,662 | 24,297 | 24,226 | 22,912 | 21,207 | 21,112 | 20,224 | 16,911 | 16,875 | 16,766 | 16,852 | 8,483 | 383 | 287 | 272 | 233 |