| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenue | ||||||||||||||||||||
- | 5,000 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Revenue | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 8,384 | 5,558 | 5,044 | 4,663 | 4,312 | 0 | 0 | 0 |
Operating expenses: | ||||||||||||||||||||
Research and development | ||||||||||||||||||||
42,689 | 52,319 | 56,935 | 62,381 | 58,060 | 50,312 | 48,877 | 46,180 | 48,946 | 53,654 | 51,833 | 48,157 | 40,191 | 33,959 | 29,285 | 26,325 | 24,897 | 22,524 | 0 | 0 | 0 |
General and administrative | ||||||||||||||||||||
13,479 | 13,835 | 14,559 | 15,555 | 15,830 | 15,710 | 14,777 | 13,368 | 12,313 | 11,660 | 12,011 | 12,536 | 12,749 | 11,880 | 10,451 | 8,708 | 7,302 | 6,322 | 0 | 0 | 0 |
Total operating expenses | ||||||||||||||||||||
56,168 | 66,154 | 71,494 | 77,936 | 73,890 | 66,022 | 63,654 | 59,548 | 61,259 | 65,314 | 63,844 | 60,693 | 52,940 | 45,839 | 39,736 | 35,033 | 32,199 | 28,846 | 0 | 0 | 0 |
Loss from operations | ||||||||||||||||||||
-56,168 | -61,154 | -66,494 | -71,881 | -66,992 | -63,182 | -59,192 | -54,590 | -55,997 | -59,973 | -56,065 | -52,750 | -44,693 | -37,455 | -34,178 | -29,989 | -27,536 | -24,534 | 0 | 0 | 0 |
Interest income | ||||||||||||||||||||
943 | 1,093 | 1,220 | 1,167 | 1,064 | 872 | 656 | 640 | 615 | 641 | 705 | 586 | 437 | 0 | 0 | 0 | - | - | - | - | - |
Interest expense | ||||||||||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 599 | 0 | 0 | 0 |
Other income, net | ||||||||||||||||||||
643 | 936 | 1,105 | 950 | 704 | 478 | 180 | 68 | 20 | -100 | -65 | -78 | -81 | -23 | 676 | 433 | 643 | 93 | 0 | 0 | 0 |
Net loss | ||||||||||||||||||||
-54,585 | -59,125 | -64,169 | -69,764 | -65,224 | -61,832 | -58,356 | -53,882 | -55,362 | -59,432 | -55,425 | -52,242 | -44,337 | -37,232 | -33,446 | -29,725 | -27,291 | -25,040 | 0 | 0 | 0 |
Accruing dividends on preferred stock | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 1,378 | 4,404 | 6,863 | 9,015 | 9,724 | 0 | 0 | 0 |
Net loss attributable to common stockholders | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | -38,610 | -37,133 | -35,698 | -26,577 | -25,035 | 0 | 0 | 0 |
Net loss per share—basic and diluted | ||||||||||||||||||||
-0.19 | -0.23 | -0.25 | -0.39 | -0.28 | -0.36 | -0.50 | -0.43 | -0.32 | -0.51 | -0.56 | -0.68 | -0.60 | -0.38 | -0.54 | -0.47 | -0.87 | - | - | - | - |
Weighted average common shares outstanding—basic and diluted | ||||||||||||||||||||
52,146 | 51,351 | 51,099 | 51,097 | 50,976 | 46,687 | 36,694 | 36,009 | 34,474 | 26,465 | 25,093 | 25,040 | 25,020 | 24,975 | 20,073 | 19,139 | 10,766 | - | - | - | - |
Other comprehensive income: | ||||||||||||||||||||
Unrealized gain on investments | ||||||||||||||||||||
25 | 6 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Comprehensive loss | ||||||||||||||||||||
-54,560 | -59,119 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |