| Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 | Dec'13 | Sep'13 | Jun'13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OPERATING ACTIVITIES: | ||||||||||||||||||||||||||
Net loss | ||||||||||||||||||||||||||
-104,640 | -103,409 | -103,780 | -105,386 | -98,890 | -92,947 | -87,279 | -82,338 | -82,548 | -93,405 | -89,070 | -85,069 | -74,274 | -52,884 | -39,959 | -33,878 | -26,786 | -59,311 | -66,597 | -59,059 | -61,851 | -22,815 | -13,176 | -10,165 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash provided by operating activities: | ||||||||||||||||||||||||||
Depreciation and amortization | ||||||||||||||||||||||||||
0 | 0 | 0 | - | 0 | 0 | 0 | - | 0 | 0 | 0 | - | 0 | 0 | 0 | - | 0 | 0 | 0 | - | 0 | 0 | 0 | - | 0 | 0 | 0 |
Share-based compensation | ||||||||||||||||||||||||||
4,756 | 4,633 | 4,788 | 4,957 | 4,274 | 4,187 | 4,218 | 4,156 | 4,590 | 4,712 | 4,608 | 4,221 | 3,713 | 3,171 | 2,565 | 2,004 | 1,704 | 1,443 | 1,249 | 1,138 | 1,046 | 1,020 | 960 | 933 | 0 | 0 | 0 |
Amortization of deferred lease rental benefit | ||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Amortization of lease incentive | ||||||||||||||||||||||||||
- | - | 0 | - | - | - | 0 | - | - | - | - | 428 | 430 | 429 | 432 | 434 | 425 | 430 | 435 | 443 | 0 | 0 | 0 | - | - | - | - |
Swiss pension obligation | ||||||||||||||||||||||||||
673 | 629 | 603 | 575 | 618 | 639 | 642 | 659 | 621 | 601 | 603 | 616 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Amortization of deferred debt issue costs | ||||||||||||||||||||||||||
9,547 | 8,790 | 7,724 | 5,908 | 5,073 | 3,636 | 3,204 | 4,359 | 4,061 | 9,150 | 7,992 | 6,774 | 6,318 | 922 | 1,506 | 1,472 | 1,439 | 1,439 | 772 | 776 | 0 | 0 | 0 | - | - | - | - |
Accrued preference share dividends | ||||||||||||||||||||||||||
1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 1,050 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Deferred income taxes | ||||||||||||||||||||||||||
52 | 49 | 46 | 44 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Change in financial liability for share warrants | ||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -15,857 | -26,472 | 11,923 | 24,774 | 22,966 | 0 | 0 | 0 | - | - | - | 0 |
Net change in assets and liabilities: | ||||||||||||||||||||||||||
Trade accounts receivable, net | ||||||||||||||||||||||||||
2,590 | 1,999 | 1,935 | 637 | 453 | 117 | 58 | 87 | 149 | -1,517 | 550 | 584 | 580 | 2,102 | 423 | 519 | -508 | -447 | -819 | -362 | 439 | 622 | -1,277 | 748 | 0 | 0 | 0 |
Inventories | ||||||||||||||||||||||||||
4,078 | 3,282 | 1,225 | 93 | -753 | 361 | 1,161 | 1,741 | 2,803 | 1,498 | 1,814 | 1,766 | 6,187 | 8,334 | 8,552 | 8,126 | 3,436 | 1,642 | 714 | 552 | 313 | 427 | 659 | 897 | 0 | 0 | 0 |
Accounts payable and accrued liabilities | ||||||||||||||||||||||||||
3,178 | 4,193 | 2,058 | 370 | -4,320 | -6,656 | -6,706 | -3,310 | -766 | 7,806 | 6,549 | 9,960 | 10,290 | 2,336 | 2,761 | 955 | 574 | 6,095 | 7,003 | 7,358 | 8,388 | 6,667 | 5,162 | 5,100 | 0 | 0 | 0 |
Accrued compensation and benefits | ||||||||||||||||||||||||||
1,517 | 48 | -1,635 | 1,121 | 1,818 | 1,465 | 3,490 | 1,596 | -23 | 208 | 93 | 778 | 1,530 | 1,780 | 652 | 812 | 289 | -24 | 888 | 772 | 400 | 1,054 | 940 | 874 | 0 | 0 | 0 |
Other assets | ||||||||||||||||||||||||||
942 | 722 | 128 | -3,297 | -1,294 | -1,091 | -2,008 | 2,083 | 57 | -613 | 777 | 1,213 | -2,628 | -1,806 | -634 | -2,603 | 1,754 | 2,650 | 2,768 | 1,760 | 3,609 | 3,145 | 1,691 | 3,470 | 0 | 0 | 0 |
Net cash used in operating activities | ||||||||||||||||||||||||||
-78,896 | -77,282 | -79,591 | -75,655 | -77,014 | -76,917 | -70,390 | -68,418 | -66,343 | -59,771 | -62,105 | -56,200 | -47,052 | -49,491 | -49,266 | -46,973 | -51,085 | -40,026 | -32,779 | -26,591 | -18,000 | -14,742 | -6,532 | -4,380 | 0 | 0 | 0 |
Increase in short-term investments | ||||||||||||||||||||||||||
0 | 0 | 0 | - | - | - | - | 78,000 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Realization of short-term investments | ||||||||||||||||||||||||||
0 | 0 | 0 | - | - | - | - | 88,395 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Purchase of property and equipment | ||||||||||||||||||||||||||
5,685 | 5,710 | 4,501 | 4,791 | 7,308 | 10,982 | 17,596 | 21,604 | 22,292 | 22,989 | 19,012 | 20,155 | 24,280 | 24,270 | 28,591 | 28,906 | 30,257 | 27,859 | 25,828 | 23,854 | 20,239 | 17,117 | 12,107 | 7,226 | 0 | 0 | 0 |
Purchase of intangible assets | ||||||||||||||||||||||||||
- | - | - | - | - | - | - | 150 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | -94 | 0 | 0 | 0 |
Net cash used in investing activities | ||||||||||||||||||||||||||
-35,133 | -7,052 | -82,045 | -89,059 | -67,820 | -50,373 | 18,919 | 3,339 | -19,992 | -33,699 | -46,693 | -36,264 | -54,361 | -24,406 | -28,662 | -28,977 | -30,306 | -27,850 | -26,016 | -24,042 | -20,435 | -17,213 | -12,015 | -7,132 | 0 | 0 | 0 |
FINANCING ACTIVITIES: | ||||||||||||||||||||||||||
Repayment of finance leases | ||||||||||||||||||||||||||
465 | 465 | 464 | 486 | 1,915 | 1,867 | 1,837 | 1,692 | 384 | 278 | 149 | 141 | -202 | -246 | -253 | -39 | 0 | 0 | 0 | - | - | - | - | -166 | 0 | 0 | 0 |
Proceeds from finance leases | ||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | - | - | - | - |
Proceeds from drawdown of new debt | ||||||||||||||||||||||||||
25,000 | 25,000 | 25,000 | 36,000 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Debt issuance costs and fees paid to noteholders | ||||||||||||||||||||||||||
-3,023 | 877 | 877 | 1,216 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Proceeds from issuance of ordinary shares and warrants | ||||||||||||||||||||||||||
92,007 | 66,159 | 112,892 | 115,024 | 113,744 | 88,960 | 41,906 | 84,984 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net cash generated from financing activities | ||||||||||||||||||||||||||
115,665 | 85,917 | 132,651 | 145,422 | 142,716 | 121,880 | 74,914 | 83,292 | 85,109 | 90,502 | 106,863 | 61,582 | 98,066 | 74,163 | 85,375 | 85,648 | 74,346 | 78,257 | 50,939 | 85,074 | 59,989 | 49,135 | 48,864 | 14,594 | 0 | 0 | 0 |
Effect of exchange rate fluctuations on cash, cash equivalents and restricted cash | ||||||||||||||||||||||||||
65 | 2,167 | 1,700 | 5,690 | 2,906 | 2,312 | 1,338 | -2,802 | -1,912 | -1,860 | -2,400 | -3,424 | -6,386 | -6,923 | -6,323 | -3,123 | -1,944 | -1,835 | -2,862 | -4,108 | -2,260 | -1,610 | -84 | -109 | 0 | 0 | 0 |
Change in cash, cash equivalents and restricted cash | ||||||||||||||||||||||||||
1,701 | 3,750 | -27,285 | -13,602 | 788 | -3,098 | 24,781 | 15,411 | -3,138 | -4,828 | -4,335 | -34,306 | -9,733 | -6,657 | 1,124 | 6,575 | -8,989 | 8,546 | -10,718 | 30,333 | 19,294 | 15,570 | 30,233 | 2,973 | 0 | 0 | 0 |
Supplemental cash flow disclosures: | ||||||||||||||||||||||||||
Income taxes paid | ||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 |
Interest paid | ||||||||||||||||||||||||||
16,362 | 14,008 | 13,990 | 11,838 | 16,511 | 10,145 | 10,145 | 10,144 | 5,083 | 4,379 | 6,091 | 1,702 | 2,388 | 3,766 | 2,499 | 2,164 | 2,481 | 1,470 | 1,371 | 1,364 | 687 | 1,080 | 734 | 637 | 0 | 0 | 0 |
Reconciliation of cash, cash equivalents and restricted cash: | ||||||||||||||||||||||||||
Proceeds from issuance of ordinary shares | ||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 45,103 | 48,977 | 35,658 | 69,879 | 0 | 0 | 0 | - | - | - | - |
Proceeds from issuance of ordinary and preference shares | ||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 |