| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
Total revenues | ||||||
7,281 | 11,284 | 13,107 | 25,098 | 10,578 | 6,141 | |
Operating expenses: | ||||||
Research and development expenses | ||||||
94,737 | 74,809 | 72,172 | 72,510 | 59,125 | 43,772 | |
Selling, general and administrative expenses | ||||||
33,544 | 25,305 | 24,635 | 25,999 | 23,383 | 17,073 | |
Total operating expenses | ||||||
128,281 | 100,114 | 96,807 | 98,509 | 82,508 | 60,845 | |
Other income | ||||||
1,888 | 2,146 | 15,430 | 1,465 | 779 | 1,022 | |
Other expense | ||||||
2,028 | 1,548 | 3,073 | - | - | - | |
Loss from operations | ||||||
-121,140 | -88,232 | -71,343 | -71,946 | -71,151 | -53,682 | |
Interest income | ||||||
3,547 | 2,729 | 117 | 70 | 121 | 220 | |
Interest expense | ||||||
3,810 | 2,160 | 2,232 | 2,172 | 2,572 | 2,019 | |
Foreign currency (losses) / gains, net | ||||||
-268 | 4,382 | -3,566 | 1,034 | -2,496 | 5,148 | |
Other non-operating (losses) / gains, net | ||||||
-2,530 | 208 | -2,435 | 785 | -7,164 | 21 | |
Loss before income tax expense | ||||||
-124,201 | -83,073 | -79,459 | -72,229 | -83,262 | -50,312 | |
Income tax (expense) / benefit | ||||||
- | 231 | -199 | 1,145 | -1,179 | -535 | |
Net loss | ||||||
-124,201 | -83,304 | -79,260 | -73,374 | -82,083 | -49,777 | |
Other comprehensive (loss) / income: | ||||||
Foreign currency translation adjustments net of tax impact of nil for the year ended December 31, 2019 (2018: $(0.2) million and 2017: $0.2 million) | ||||||
570 | -5,261 | 2,757 | 271 | -1,556 | -5,387 | |
Total comprehensive loss | ||||||
-123,631 | -88,565 | -76,503 | -73,103 | -83,639 | -55,164 | |
Basic and diluted net loss per ordinary share | ||||||
-3,110.00 | -2,340.00 | -2,940.00 | -2.93 | -3.72 | -2.91 | |
Weighted average shares used in computing basic and diluted net loss per ordinary share | ||||||
39,999 | 35,639 | 26,984 | 25,036 | 22,082 | 17,121 | |
License revenues | ||||||
Total revenues | ||||||
- | - | 8 | 975 | - | - | |
License revenues from related party | ||||||
Total revenues | ||||||
5,000 | 7,500 | 4,100 | 3,940 | 3,335 | 1,173 | |
Collaboration revenues | ||||||
Total revenues | ||||||
- | - | 4,638 | 7,164 | - | - | |
Collaboration revenues from related party | ||||||
Total revenues | ||||||
2,300 | 3,800 | 4,300 | 13,019 | 7,243 | 4,968 | |