| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total revenues | ||||||||||||||||
104 | 2,625 | 1,046 | 2,474 | 1,136 | 1,608 | 3,148 | 3,050 | 3,478 | 2,584 | 2,260 | 4,942 | 3,321 | 9,131 | 7,221 | 4,451 | 4,295 |
Operating expenses: | ||||||||||||||||
Research and development expenses | ||||||||||||||||
26,013 | 26,492 | 23,554 | 24,154 | 20,537 | 18,717 | 20,541 | 18,493 | 17,058 | 18,209 | 20,103 | 16,866 | 16,994 | 19,979 | 16,604 | 19,221 | 16,706 |
Selling, general and administrative expenses | ||||||||||||||||
9,072 | 8,678 | 8,929 | 7,870 | 8,067 | 7,210 | 5,898 | 5,896 | 6,301 | 7,283 | 5,584 | 5,410 | 6,358 | 5,754 | 5,113 | 7,834 | 7,298 |
Total operating expenses | ||||||||||||||||
35,085 | 35,170 | 32,483 | 32,024 | 28,604 | 25,927 | 26,439 | 24,389 | 23,359 | 25,492 | 25,687 | 22,276 | 23,352 | 25,733 | 21,717 | 27,055 | 24,004 |
Other income | ||||||||||||||||
857 | 556 | 453 | 566 | 313 | 409 | 557 | 565 | 615 | 435 | 14,413 | 266 | 316 | 209 | 336 | 475 | 445 |
Other expense | ||||||||||||||||
339 | 990 | 342 | 347 | 349 | 296 | 490 | 429 | 333 | - | 261 | 2,640 | - | - | - | - | - |
Loss from operations | ||||||||||||||||
-34,463 | -32,979 | -31,326 | -29,331 | -27,504 | -24,206 | -23,224 | -21,203 | -19,599 | -22,645 | -9,275 | -19,708 | -19,715 | -16,393 | -14,160 | -22,129 | -19,264 |
Interest income | ||||||||||||||||
822 | 1,509 | 868 | 728 | 442 | 944 | 949 | 583 | 253 | 84 | 10 | 12 | 11 | 19 | 14 | 15 | 22 |
Interest expense | ||||||||||||||||
975 | 956 | 960 | 937 | 957 | 664 | 515 | 565 | 416 | 649 | 577 | 502 | 504 | 487 | 507 | 549 | 629 |
Foreign currency (losses) / gains, net | ||||||||||||||||
4,602 | -7,331 | 6,041 | -1,252 | 2,274 | 1,494 | 455 | 2,255 | 178 | -1,721 | -681 | -1,071 | -93 | 2,798 | -496 | 920 | -2,188 |
Other non-operating (losses) / gains, net | ||||||||||||||||
2,015 | -1,669 | 1,773 | -607 | -2,027 | 538 | 268 | -1,301 | 703 | -2,464 | 0 | 0 | 29 | 84 | 54 | 330 | 317 |
Loss before income tax expense | ||||||||||||||||
- | - | -23,604 | -31,399 | - | -21,894 | -22,067 | -20,231 | -18,881 | -27,395 | -10,523 | -21,269 | -20,272 | -13,979 | -15,095 | -21,413 | -21,742 |
Income tax (expense) / benefit | ||||||||||||||||
- | - | - | - | - | -6 | -32 | 361 | -92 | - | -278 | - | - | 744 | 177 | -333 | 557 |
Net loss | ||||||||||||||||
-27,999 | -41,426 | -23,604 | -31,399 | -27,772 | -21,888 | -22,035 | -20,592 | -18,789 | -27,474 | -10,245 | -21,269 | -20,272 | -14,723 | -15,272 | -21,080 | -22,299 |
Other comprehensive (loss) / income: | ||||||||||||||||
Foreign currency translation adjustments net of tax impact of nil for the year ended December 31, 2019 (2018: $(0.2) million and 2017: $0.2 million) | ||||||||||||||||
-5,277 | 3,057 | -6,164 | 1,209 | 2,468 | -907 | -799 | -3,376 | -179 | 2,009 | 22 | 404 | 322 | -3,109 | 2,801 | -4,101 | 4,680 |
Total comprehensive loss | ||||||||||||||||
-33,276 | -38,369 | -29,768 | -30,190 | -25,304 | -22,795 | -22,834 | -23,968 | -18,968 | -25,465 | -10,223 | -20,865 | -19,950 | -17,832 | -12,471 | -25,181 | -17,619 |
Basic and diluted net loss per ordinary share | ||||||||||||||||
-0.63 | -2,278.68 | -0.58 | -830.00 | -0.74 | -1,179.41 | -0.59 | -570.00 | -590.00 | -2,937.97 | -0.40 | -0.83 | -0.80 | -0.58 | -0.61 | -0.84 | -0.90 |
Weighted average shares used in computing basic and diluted net loss per ordinary share | ||||||||||||||||
44,279 | 43,757 | 40,738 | 37,824 | 37,676 | 37,396 | 37,247 | 36,205 | 31,710 | 31,300 | 25,632 | 25,560 | 25,443 | 25,229 | 25,142 | 25,077 | 24,696 |
License revenues | ||||||||||||||||
Total revenues | ||||||||||||||||
- | - | - | - | - | - | - | - | - | 0 | 0 | -226 | 234 | 238 | 246 | 250 | 241 |
License revenues from related party | ||||||||||||||||
Total revenues | ||||||||||||||||
0 | 1,492 | 800 | 2,108 | 600 | 426 | 2,500 | 2,123 | 2,451 | 1,040 | 1,124 | 987 | 949 | 963 | 993 | 1,006 | 978 |
Collaboration revenues | ||||||||||||||||
Total revenues | ||||||||||||||||
- | - | - | - | - | - | - | - | - | 0 | 0 | 3,058 | 1,580 | 2,330 | 1,850 | 1,558 | 1,426 |
Collaboration revenues from related party | ||||||||||||||||
Total revenues | ||||||||||||||||
57 | 1,151 | 204 | 366 | 579 | 1,216 | 630 | 927 | 1,027 | 1,483 | 1,136 | 1,123 | 558 | 5,600 | 4,132 | 1,637 | 1,650 |