| Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | |||||||||||||||
Net loss | |||||||||||||||
-102,688 | -82,106 | -73,635 | -67,484 | -64,943 | -63,889 | -62,660 | -59,577 | -54,439 | -50,186 | -43,025 | -35,168 | -28,864 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | |||||||||||||||
Depreciation and amortization | |||||||||||||||
1,619 | 2,017 | 1,888 | 1,741 | 1,597 | 1,589 | 1,566 | 1,564 | 1,524 | 1,394 | 1,335 | 1,349 | 1,274 | 0 | 0 | 0 |
Stock-based compensation | |||||||||||||||
14,045 | 12,290 | 10,272 | 8,639 | 7,695 | 7,279 | 7,081 | 6,501 | 5,573 | 4,352 | 3,005 | 1,919 | 1,026 | 0 | 0 | 0 |
Other, net | |||||||||||||||
-74 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | -84 | 0 | 0 | 0 |
Changes in operating assets and liabilities: | |||||||||||||||
Prepaid expenses and other current assets | |||||||||||||||
6,985 | 5,118 | 2,981 | 2,067 | 49 | 1,343 | 1,870 | 345 | 1,023 | 591 | 158 | -1,253 | 890 | 0 | 0 | 0 |
Accounts payable and accrued expenses | |||||||||||||||
7,020 | 3,041 | 2,875 | 2,290 | 1,126 | 292 | 1,415 | 1,961 | 2,012 | 2,074 | 1,423 | 1,879 | 4,018 | 0 | 0 | 0 |
Operating lease liabilities | |||||||||||||||
-1,007 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Deferred rent | |||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | -2,389 | 0 | 0 | 0 |
Deferred revenue | |||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | -1,862 | 0 | 0 | 0 |
Other, net | |||||||||||||||
- | - | - | - | 19 | 36 | 26 | -8 | 19 | 0 | 0 | 0 | - | - | - | - |
Net cash used in operating activities | |||||||||||||||
-87,361 | -70,824 | -62,292 | -57,451 | -54,946 | -56,523 | -54,908 | -50,295 | -46,779 | -42,152 | -37,433 | -28,195 | -21,843 | 0 | 0 | 0 |
Purchase of property and equipment | |||||||||||||||
865 | 748 | 892 | 1,200 | 1,034 | 937 | 842 | 962 | 1,412 | 2,001 | 3,012 | 5,527 | 5,105 | 0 | 0 | 0 |
Net cash used in investing activities | |||||||||||||||
-865 | -748 | -892 | -1,200 | -1,034 | -937 | -842 | -962 | -1,412 | -2,128 | -3,136 | -5,521 | -5,096 | 0 | 0 | 0 |
Cash flows from financing activities | |||||||||||||||
Proceeds from common stock offering, net of underwriter discounts | |||||||||||||||
- | - | - | - | 195,014 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Proceeds from sale of property and equipment | |||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 |
Payment of common stock offering costs | |||||||||||||||
540 | 572 | 618 | 451 | 403 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Payments related to restricted stock units vesting | |||||||||||||||
583 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Proceeds from exercises of stock options and ESPP shares | |||||||||||||||
3,989 | 0 | 0 | 0 | - | - | - | - | 266 | 0 | 0 | 0 | - | - | - | - |
Net cash provided by financing activities | |||||||||||||||
143,396 | 283,115 | 141,730 | 141,176 | 195,421 | 54,428 | 54,202 | 55,006 | 760 | 0 | 0 | 0 | - | - | - | - |
Net change in cash, cash equivalents and restricted cash | |||||||||||||||
55,170 | 211,543 | 78,546 | 82,525 | 139,441 | -3,032 | -1,548 | 3,749 | -47,431 | 0 | 0 | 0 | - | - | - | 0 |
Noncash investing and financing activity: | |||||||||||||||
Common stock offering costs incurred but unpaid at period end | |||||||||||||||
- | - | - | - | - | - | - | 0 | - | - | - | - | - | - | - | - |
Changes in liabilities and prepaid expenses related to fixed asset additions | |||||||||||||||
- | - | - | 0 | - | - | - | 0 | - | - | - | - | - | - | - | - |