| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
Revenue | ||||||
0 | 0 | 0 | 0 | - | - | |
Operating expenses: | ||||||
Research and development | ||||||
58,623 | 53,270 | 14,917 | 5,994 | 12,554 | 5,592 | |
General and administrative | ||||||
17,528 | 17,886 | 4,855 | 1,580 | 7,842 | 2,112 | |
Total operating expenses | ||||||
76,151 | 71,156 | 19,772 | 7,574 | - | - | |
Loss from operations | ||||||
-76,151 | -71,156 | -19,772 | -7,574 | -20,396 | -7,704 | |
Amount of research and development income claimed from tax credit against the General Corporation Tax and Unincorporated Business Tax during the period. | ||||||
250 | 186 | 192 | 0 | - | - | |
Interest expense | ||||||
5,958 | 6,039 | 0 | 0 | 1,230 | 980 | |
Interest and other income net | ||||||
3,414 | 1,690 | 2 | 1 | - | - | |
Accretion of discount on investments | ||||||
1,175 | 801 | 0 | 0 | - | - | |
Interest income | ||||||
- | - | - | - | 89 | - | |
Loss on extinguishment of debt | ||||||
- | - | - | - | -4,399 | - | |
Change in fair value of warrant liabilities | ||||||
- | - | - | - | -267 | 845 | |
Change in fair value of Convertible Bridge Notes redemption rights derivative | ||||||
- | - | - | - | -480 | 2 | |
Change in fair value of 2020 Convertible Notes derivative liability | ||||||
- | - | - | - | -42,793 | - | |
Net loss | ||||||
-77,270 | -74,518 | -19,578 | -7,573 | -67,982 | -9,531 | |
Net loss per share attributable to common stockholders - basic and diluted (in dollars per share) | ||||||
-1.58 | -1.89 | -2.88 | -1.11 | -3.72 | -13.52 | |
Weighted-average common shares outstanding - basic and diluted (in shares) | ||||||
49,010 | 39,377 | 6,795 | 6,833 | 18,311 | 1,020 | |