| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Jun'14 | Mar'14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenue | ||||||||||||||||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - |
Operating expenses: | ||||||||||||||||||||||
Research and development | ||||||||||||||||||||||
16,957 | 14,668 | 14,829 | 13,989 | 15,137 | 23,690 | 13,065 | 10,772 | 5,743 | 4,919 | 4,894 | 2,819 | 2,285 | -16,498 | 8,412 | 6,465 | 7,615 | 5,919 | 3,612 | 1,954 | 1,069 | 1,862 | 1,550 |
General and administrative | ||||||||||||||||||||||
7,163 | 4,981 | 4,336 | 4,403 | 3,808 | 2,856 | 2,268 | 4,100 | 8,662 | 1,737 | 1,831 | 702 | 585 | -5,568 | 2,311 | 2,315 | 2,522 | 2,309 | 1,825 | 1,728 | 1,980 | 332 | 162 |
Total operating expenses | ||||||||||||||||||||||
24,120 | 19,649 | 19,165 | 18,392 | 18,945 | 26,546 | 15,333 | 14,872 | 14,405 | 6,656 | 6,725 | 3,521 | 2,870 | - | - | - | - | - | - | - | - | - | - |
Loss from operations | ||||||||||||||||||||||
-24,120 | -19,649 | -19,165 | -18,392 | -18,945 | -26,546 | -15,333 | -14,872 | -14,405 | -6,656 | -6,725 | -3,521 | -2,870 | 22,066 | -10,723 | -8,780 | -10,137 | -8,228 | -5,437 | -3,682 | -3,049 | -2,194 | -1,712 |
Amount of research and development income claimed from tax credit against the General Corporation Tax and Unincorporated Business Tax during the period. | ||||||||||||||||||||||
0 | 0 | 0 | 0 | 250 | 0 | 0 | 0 | 186 | -192 | 0 | 192 | 192 | - | - | - | - | - | - | - | - | - | - |
Interest expense | ||||||||||||||||||||||
1,573 | 1,344 | 1,466 | 1,544 | 1,604 | 2,073 | 1,176 | 1,363 | 1,427 | 0 | 0 | 0 | 0 | - | 525 | - | - | 0 | 192 | 564 | 474 | 248 | 243 |
Interest and other income net | ||||||||||||||||||||||
967 | 834 | 979 | 1,000 | 601 | 514 | 420 | 468 | 288 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Accretion of discount on investments | ||||||||||||||||||||||
62 | 304 | 368 | 256 | 247 | 786 | 0 | 0 | 15 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Interest income | ||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 2 | 0 | 0 | - | 120 | 96 | 69 | - | 33 | - | - | - | - |
Other income / (expense) net | ||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - |
Loss on extinguishment of debt | ||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | -3,716 | 0 | -683 | - | - |
Change in fair value of warrant liabilities | ||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | -267 | 405 | 193 |
Change in fair value of Convertible Bridge Notes redemption rights derivative | ||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | -480 | - | - |
Change in fair value of 2020 Convertible Notes derivative liability | ||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | -46,649 | 1,859 | 1,997 | - | - |
Net loss | ||||||||||||||||||||||
-24,664 | -19,855 | -19,284 | -18,680 | -19,451 | -27,319 | -16,089 | -15,767 | -15,343 | -6,848 | -6,723 | -3,329 | -2,678 | 22,307 | -11,128 | -8,684 | -10,068 | -8,172 | -55,961 | -2,387 | -1,462 | -2,847 | -2,148 |
Net loss per share attributable to common stockholders - basic and diluted (in dollars per share) | ||||||||||||||||||||||
-0.45 | -0.39 | -0.38 | -0.38 | -0.43 | -0.67 | -0.40 | -0.40 | -0.42 | -1.01 | -0.99 | -0.49 | -0.39 | 0.01 | -0.41 | -0.33 | -0.38 | -0.88 | -2.48 | -0.15 | -0.21 | -3.81 | -3.08 |
Weighted-average common shares outstanding - basic and diluted (in shares) | ||||||||||||||||||||||
54,883 | 51,286 | 50,364 | 49,267 | 45,122 | 41,989 | 39,900 | 39,483 | 36,137 | 6,795 | 6,795 | 6,795 | 6,795 | -52,642 | 26,930 | 26,623 | 26,423 | 26,667 | 22,573 | 16,327 | 7,677 | 1,020 | 1,020 |