| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flow from operating activities | ||||||||||||
Net loss | ||||||||||||
-27,753 | -16,598 | -22,352 | -28,090 | -17,670 | -12,295 | -10,811 | -13,534 | -12,954 | -13,210 | -23,122 | -9,550 | -7,200 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||||
Stock-based compensation expense | ||||||||||||
3,462 | 2,437 | 2,740 | 2,130 | 1,674 | 1,054 | 1,048 | 1,116 | 656 | 155 | 137 | 131 | 72 |
Depreciation and amortization | ||||||||||||
842 | 856 | 886 | 883 | 953 | 947 | 974 | 915 | 828 | 766 | 732 | 628 | 486 |
Share of loss from equity method investee | ||||||||||||
-482 | 0 | -358 | -413 | -431 | -323 | -186 | -151 | -226 | -156 | -119 | -71 | -70 |
Gain on deemed sale from equity method investee | ||||||||||||
482 | 0 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Amortization of premiums on investments | ||||||||||||
248 | 425 | 633 | 833 | 747 | 735 | 1,017 | 0 | 0 | - | - | - | - |
Other non-operating income | ||||||||||||
- | - | - | - | - | 0 | 0 | 118 | 59 | 22 | 23 | 23 | 30 |
Changes in operating assets and liabilities: | ||||||||||||
Receivable from collaboration partners | ||||||||||||
212 | - | - | - | 0 | - | - | - | - | - | - | - | - |
Amounts owed by a related party | ||||||||||||
0 | 0 | -62 | 62 | -83 | -31 | -79 | 139 | 29 | -10 | 14 | 21 | -405 |
Prepaid expenses and other current assets | ||||||||||||
3,704 | 80 | 950 | 193 | 759 | -8 | 779 | -284 | 693 | -537 | 922 | 270 | 96 |
Other long-term assets | ||||||||||||
91 | 609 | -56 | 5 | 30 | 80 | 0 | 0 | 0 | - | - | - | - |
Accounts payable | ||||||||||||
-2,342 | 1,820 | 472 | -49 | -517 | 960 | -2,376 | 1,653 | -306 | 2,039 | -696 | 1,082 | -2,692 |
Accrued liabilities | ||||||||||||
648 | -140 | -5,890 | 7,923 | 1,606 | -644 | 2,329 | 1,402 | 410 | 971 | -210 | 1,290 | -469 |
Other current liabilities | ||||||||||||
0 | 15 | 13 | 15 | 14 | 10 | 13 | 11 | 9 | -164 | 8 | 10 | 10 |
Deferred revenue | ||||||||||||
-1,750 | -1,750 | 3,250 | -1,750 | -1,750 | -1,562 | 3,709 | -1,250 | -1,250 | - | - | - | - |
Deferred rent | ||||||||||||
-129 | -141 | -135 | -135 | -127 | -124 | -120 | -139 | -85 | 687 | -162 | -163 | -153 |
Net cash used in operating activities | ||||||||||||
-31,277 | -9,471 | -27,399 | -19,753 | -16,839 | -7,107 | -11,765 | -10,877 | -13,247 | 15,587 | -24,234 | -6,815 | -9,597 |
Cash flow from investing activities | ||||||||||||
Purchases of short-term and long-term investments | ||||||||||||
8,885 | 67,510 | 56,408 | 51,430 | 72,407 | 39,485 | 131,396 | 49,587 | 41,084 | 59,112 | 6,278 | 10,086 | 21,354 |
Proceeds from maturities of short-term and long-term investments | ||||||||||||
49,150 | 55,602 | 87,322 | 78,654 | 87,314 | 42,254 | 49,186 | 34,768 | 25,647 | 17,340 | 19,848 | 9,085 | 7,000 |
Purchases of property and equipment | ||||||||||||
209 | 196 | 550 | 551 | 628 | 258 | 1,127 | 1,304 | 1,054 | 294 | 839 | 2,242 | 2,139 |
Net cash provided by investing activities | ||||||||||||
40,056 | -12,104 | 30,364 | 26,673 | 14,279 | 2,511 | -83,337 | -16,123 | -16,491 | -42,066 | 12,731 | -3,243 | -16,493 |
Cash flow from financing activities | ||||||||||||
Proceeds from initial public offering, net of issuance costs | ||||||||||||
- | - | - | - | - | 0 | -3 | -1,145 | 126,259 | - | - | - | - |
Proceeds from issuance of common stock | ||||||||||||
643 | - | - | - | 0 | - | - | - | - | - | - | - | - |
Repurchase of unvested shares of stock | ||||||||||||
33 | - | 43 | 46 | 5 | - | 0 | 0 | 0 | - | - | - | - |
Proceeds from issuance of common stock upon exercise of stock options, net of repurchases | ||||||||||||
- | - | - | - | - | - | -4 | 27 | 3,304 | 95 | 189 | 579 | 29 |
Payment of preferred stock issuance costs | ||||||||||||
- | - | - | - | - | 0 | 0 | 0 | 135 | - | - | - | - |
Net cash provided by (used in) financing activities | ||||||||||||
610 | 520 | -41 | 649 | -5 | 771 | -7 | -1,118 | 129,428 | 106,599 | 189 | 579 | 29 |
Net increase (decrease) in cash and cash equivalents | ||||||||||||
9,389 | -21,055 | 2,924 | 7,569 | -2,565 | -3,825 | -95,109 | -28,118 | 99,690 | 80,120 | -11,314 | -9,479 | -26,061 |
Non-cash investing and financing activities: | ||||||||||||
Unpaid financing cost included in accounts payable and accrued liabilities | ||||||||||||
- | - | - | - | - | - | - | - | 1,170 | - | - | - | - |
Unpaid portion of property and equipment purchases included in accounts payable and accrued liabilities | ||||||||||||
76 | -21 | -15 | -332 | 380 | 33 | -904 | 312 | 695 | 315 | -472 | -605 | 1,100 |
Vesting of early exercised stock options and restricted stock | ||||||||||||
220 | 245 | 251 | 260 | 273 | 294 | 335 | 369 | 278 | 95 | 54 | 64 | 22 |