| Dec'19 | Dec'18 | Dec'17 | Dec'16 | |||
|---|---|---|---|---|---|---|
Collaboration and license revenue | ||||||
15,000 | 8,353 | 1,413 | - | |||
Operating expenses: | ||||||
Research and development | ||||||
78,481 | 49,646 | 47,218 | 14,247 | |||
General and administrative | ||||||
25,228 | 13,566 | 7,636 | 3,935 | |||
Total operating expenses | ||||||
103,709 | 63,212 | 54,854 | 18,182 | |||
Loss from operations | ||||||
-88,709 | -54,859 | -53,441 | -18,182 | |||
Non-operating income (expense): | ||||||
Non-operating income (expense): | ||||||
Interest and other income, net | ||||||
5,201 | 4,922 | 775 | 212 | |||
Gain on deemed sale from equity method investee | ||||||
0 | 1,229 | 0 | 0 | |||
Share of loss from equity method investee | ||||||
-1,202 | -886 | -416 | 0 | |||
Total non-operating income, net | ||||||
3,999 | 5,265 | 359 | 212 | |||
Net loss | ||||||
-84,710 | -49,594 | -53,082 | -17,970 | |||
Other comprehensive income | ||||||
171 | -65 | -16 | -26 | |||
Comprehensive loss | ||||||
-84,539 | -49,659 | -53,098 | -17,996 | |||
Net loss per share, basic and diluted | ||||||
-1.93 | -1.43 | -29.03 | -20.80 | |||
Weighted-average number of shares used to compute basic and diluted net loss per share | ||||||
43,825 | 34,618 | 1,828 | 863 | |||