| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Collaboration and license revenue | ||||||||||||
0 | - | - | - | 0 | - | - | - | - | - | - | - | - |
Collaboration and license revenue | ||||||||||||
- | - | 6,812 | 9,353 | - | 8,353 | 0 | 0 | 0 | - | 0 | - | - |
Operating expenses: | ||||||||||||
Research and development | ||||||||||||
86,069 | 78,481 | 69,230 | 64,848 | 53,548 | 49,646 | 50,355 | 58,931 | 53,066 | 47,218 | 0 | 0 | 0 |
General and administrative | ||||||||||||
27,267 | 25,228 | 22,248 | 18,067 | 15,606 | 13,566 | 12,404 | 10,689 | 9,069 | 7,636 | 0 | 0 | 0 |
Total operating expenses | ||||||||||||
113,336 | 103,709 | 91,478 | 82,915 | 69,154 | 63,212 | 62,759 | 69,620 | 62,135 | 54,854 | 0 | 0 | 0 |
Loss from operations | ||||||||||||
-98,336 | -88,709 | -84,666 | -73,562 | -60,301 | -54,859 | -54,718 | -65,707 | -59,472 | -53,441 | 0 | 0 | 0 |
Non-operating income (expense): | ||||||||||||
Non-operating income (expense): | ||||||||||||
Interest and other income, net | ||||||||||||
4,314 | 5,201 | 5,782 | 6,047 | 5,853 | 4,922 | 0 | 0 | 0 | - | - | - | - |
Gain on deemed sale from equity method investee | ||||||||||||
482 | 0 | 0 | 1,229 | 0 | - | 0 | 0 | - | - | - | - | - |
Share of loss from equity method investee | ||||||||||||
-1,253 | -1,202 | -1,523 | -1,352 | -1,091 | -886 | 0 | 0 | 0 | - | - | - | - |
Total non-operating income, net | ||||||||||||
3,543 | 3,999 | 4,259 | 4,695 | 5,991 | 5,265 | 4,209 | 2,888 | 636 | 359 | 0 | 0 | 0 |
Net loss | ||||||||||||
-94,793 | -84,710 | -80,407 | -68,867 | -54,310 | -49,594 | -50,509 | -62,819 | -58,836 | -53,082 | 0 | 0 | 0 |
Other comprehensive income | ||||||||||||
259 | 171 | 162 | 196 | 126 | -65 | -99 | -60 | -63 | -16 | 0 | 0 | 0 |
Comprehensive loss | ||||||||||||
-94,534 | -84,539 | -80,245 | -68,671 | -54,184 | -49,659 | -50,608 | -62,879 | -58,899 | -53,098 | 0 | 0 | 0 |
Net loss per share, basic and diluted | ||||||||||||
-0.63 | -0.37 | -0.51 | -0.64 | -0.41 | 0.51 | -0.25 | -0.32 | -1.37 | -6.57 | -11.86 | -5.64 | -4.96 |
Weighted-average number of shares used to compute basic and diluted net loss per share | ||||||||||||
44,282 | 44,058 | 43,939 | 43,797 | 43,508 | 43,612 | 42,838 | 42,533 | 9,488 | 2,218 | 1,949 | 1,693 | 1,452 |