Regulus therapeutics inc. (RGLS)
CashFlow / TTM
Mar'20Dec'19Sep'19Jun'19Mar'19Dec'18Sep'18Jun'18Mar'18Dec'17Sep'17Jun'17Mar'17Dec'16Sep'16Jun'16Mar'16Dec'15Sep'15Jun'15Mar'15Dec'14Sep'14Jun'14Mar'14Dec'13Sep'13Jun'13Mar'13Dec'12Sep'12Jun'12Mar'12
Operating activities
Net loss

-21,269

-18,592

-22,262

-27,112

-35,944

-48,709

-54,594

-60,149

-67,909

-71,905

-77,477

-81,169

-80,650

-81,836

-69,042

-62,522

-62,468

-55,748

-70,690

-67,488

-58,426

-56,680

-36,439

-28,805

-24,180

-18,668

0

0

0

-

-

-

-

Net loss

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

0

0

Adjustments to reconcile net loss to net cash used in operating activities
Depreciation and amortization expense

524

900

1,428

1,852

2,239

2,300

2,254

2,288

2,388

2,524

2,629

2,705

2,556

2,276

2,003

1,721

1,616

1,591

1,569

1,588

1,530

1,490

1,462

1,431

1,425

1,360

1,272

1,165

1,081

1,017

0

0

0

Loss from valuation of convertible note payable

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-1,811

-14,543

-12,758

-11,805

-12,118

3,256

2,142

-1,508

-1,145

0

0

0

-

-

-

-

Stock-based compensation

2,152

2,288

2,883

3,735

4,773

5,441

5,485

5,379

6,888

7,642

9,950

12,133

11,504

12,872

13,214

12,382

16,014

15,368

13,936

12,928

8,742

7,039

5,608

4,959

4,035

3,422

3,342

2,778

2,224

1,550

0

0

0

Amortization of premium on investments, net

-

-

-

-

-

-148

-170

-255

-289

-349

-412

-488

-575

-666

-867

-1,030

-1,245

-1,472

-1,492

-1,522

-1,580

-1,597

-1,662

-1,668

-1,557

-1,439

0

0

0

-

-

-

-

Gain on reduction of lease liability

522

1,839

1,839

1,839

1,317

0

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Other

259

293

836

798

802

756

576

519

558

600

911

1,188

1,178

1,043

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Amortization of premium on investments, net

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

Gain on investments

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

-

-

-

-

Loss on disposal of long-term assets

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

-

0

0

0

-

-

0

0

-

-

-

-

Deferred income taxes

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

0

-

-

-

-

Change in operating assets and liabilities:
Contracts and other receivables

-2,117

1,115

686

147

2,604

-347

-520

-506

-251

-1,284

247

547

377

-8,364

-39

-182

-2,682

9,746

0

0

0

-

-

-

0

-

-

-

-

-

-

-

-

Prepaid materials

98

-270

87

-374

-374

-134

-1,343

-1,119

-1,182

-394

-353

4,047

2,869

616

4,673

1,452

1,719

3,460

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

Prepaid expenses and other assets

461

242

-152

-1,282

-1,136

-630

-1,014

-1,494

-1,768

-2,369

-2,261

-2,298

-2,217

778

1,342

2,673

3,277

683

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

Prepaid and other current assets

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

0

0

-

876

1,133

634

308

0

0

0

Accounts payable

-1,620

-393

287

-3,865

-1,746

-4,029

-3,995

566

-81

-65

-463

1,429

886

3,123

2,512

1,186

964

529

494

-659

-108

940

1,501

1,872

2,293

860

492

268

-115

-189

0

0

0

Accrued liabilities

-885

-708

-705

-921

-1,627

-1,370

-978

-605

703

-492

-336

-622

-1,093

-871

-742

-1,428

599

2,094

1,595

1,603

1,494

556

1,114

2,607

494

1,355

758

177

1,039

-20

0

0

0

Accrued compensation

-1,383

75

-367

-395

798

-384

-395

-209

-189

-333

-603

-430

95

-74

291

-412

162

284

555

1,087

190

811

216

167

99

-51

255

233

254

677

0

0

0

Operating lease liabilities

-

-

-

-

-

-

-

-

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Contract liabilities

-60

-2,572

-72

-72

-72

2,428

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Deferred revenue

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-2,009

-2,739

-3,190

-3,090

-6,316

-4,466

-4,267

-5,039

-6,184

-10,718

-14,742

-16,819

-10,602

-1,044

407

486

0

0

0

Deferred rent

-

-

-

-

-

-1,252

-1,583

-1,494

-1,363

-1,068

-97

218

51

143

-300

-481

-213

-379

-336

-318

-300

-282

-282

-1,190

-138

-11

350

1,183

298

337

0

0

0

Other liabilities

-1,219

-1,895

-1,806

-2,338

-661

325

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Net cash used in operating activities

-21,390

-19,821

-18,861

-25,586

-32,104

-43,273

-50,357

-50,577

-55,695

-58,773

-62,779

-66,614

-66,632

-56,882

-58,819

-55,119

-47,537

-49,859

0

0

0

-

-

-

-

-

-

-

0

-

0

0

0

Net cash used in operating activities

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

0

0

-

-

-

-

-

-

-

-

Investing activities
Purchases of short-term investments

-

-

-

-

-

-

-

-

-

55,686

52,933

39,332

46,900

65,110

72,053

62,351

61,719

78,401

128,213

111,397

110,794

113,417

73,883

100,322

93,711

72,005

103,144

74,950

75,503

62,041

0

0

0

Sales and maturities of short-term investments

-

-

-

-

-

46,541

51,732

59,163

60,600

69,941

78,260

91,794

89,595

101,387

106,332

99,183

103,868

101,306

98,758

84,946

86,059

85,421

78,505

68,751

58,893

31,951

25,053

32,622

24,402

33,083

0

0

0

Purchases of property and equipment

-

-

-

-

-

-

-

-

-

303

384

771

657

913

1,236

1,219

1,522

1,363

899

825

1,307

1,146

1,312

1,263

798

800

1,035

685

874

1,151

0

0

0

Sales of property and equipment

-

-

-

-

-

-

-

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Sales of property and equipment

0

-

-

-

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Acquisition of intangibles

-

-

-

-

-

-

-

-

-

16

21

35

58

53

75

82

71

67

0

0

0

-

-

-

-

35

136

241

280

275

0

0

0

Net cash provided by investing activities

-87

74

6,573

19,642

35,241

46,519

44,477

7,751

7,015

13,936

24,922

51,656

41,980

35,311

32,968

35,531

40,556

21,475

0

0

0

-

-

-

-

-

-

-

0

-

0

0

0

Net cash provided by investing activities

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

0

0

-

-

-

-

-

-

-

-

Proceeds from issuance of common stock, net

1

2,086

2,087

2,097

2,097

219

219

43,354

43,354

43,411

43,411

543

543

641

641

598

598

492

76,785

76,675

76,675

86,146

9,271

55,419

55,623

45,980

112,248

66,043

65,840

65,788

0

0

0

Principal payments on term loan

613

1,977

4,486

5,319

4,706

3,342

0

0

0

-

-

-

-

167

164

163

159

155

151

147

145

142

122

114

106

100

203

285

366

445

0

0

0

Proceeds from Stock Options Exercised

-

-

-

-

-

1

2

2

2

4

5

48

107

310

1,988

5,290

6,191

6,680

6,610

3,332

2,441

2,233

0

0

0

-

-

-

0

-

-

-

-

Proceeds from financing leases

-

-

-

-

-

-

-

-

492

0

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Payments on financing leases

0

-

-

-

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Payments on financing leases

-

-

-

-

-

-

-

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Net cash (used in) provided by financing activities

39,209

39,933

12,850

12,030

-2,874

-2,830

-258

43,773

43,848

43,415

43,373

456

20,292

20,552

22,233

25,544

6,630

7,017

0

0

0

-

-

-

-

-

-

-

0

-

0

0

0

Net decrease in cash and cash equivalents

0

-

-

-

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Net cash provided by financing activities

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

0

0

-

-

-

-

-

-

-

-

Net increase (decrease) in cash and cash equivalents

-

-

-

-

-

-

-

947

-4,832

-1,422

5,516

-14,502

-4,360

-1,019

-3,618

5,956

-351

-21,367

8,366

11,060

11,124

19,520

-23,532

-9,146

-9,346

-22,745

16,064

14,242

7,726

31,377

0

0

0

Supplemental disclosure of cash flow information
Net changes in restricted cash

-

-

-

-

-

-

-

-

-

-

-

-

-

-1,256

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Interest paid

0

-

-

-

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Net changes in restricted cash

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

-

-

-

-

-

-

-

-

-

-

-

-

Interest paid

-

-

-

-

-

-

-

0

0

-

0

0

1,441

-

523

66

24

27

31

33

36

39

0

0

0

-

-

-

-

8

0

0

0

Income taxes paid

-

-

-

-

-

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

0

0

0

-

-

-

-

208

0

0

0

Supplemental disclosure of non-cash investing and financing activities
Non-cash acquisition of property and equipment

-

-

-

-

-

-

0

0

0

-

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Allowance for tenant improvements

-

-

-

-

-

-

-

-

-

-

-

-

-

6,653

8,309

8,201

7,126

1,656

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

Non-cash acquisition of property and equipment

-

-

-

-

-

-

-

-

-

-

-

181

215

292

58

354

295

223

255

49

-211

76

-57

12

7

0

0

0

0

-

-

-

-

Allowance for tenant improvements

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

-

-

-

-

Amounts accrued for patent expenditures

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

0

-

-

-

-