| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 |
|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||||
Net loss | ||||||||
-179,363 | -163,458 | -146,169 | -125,516 | -107,365 | -89,195 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||
Stock-based compensation expense | ||||||||
40,281 | 41,271 | 39,566 | 39,095 | 34,393 | 27,528 | 0 | 0 | 0 |
Depreciation and amortization expense | ||||||||
4,123 | 2,995 | 2,678 | 2,207 | 1,697 | 1,263 | 0 | 0 | 0 |
Change in fair value of preferred stock warrant liability | ||||||||
- | - | - | - | - | 2,187 | 0 | 0 | 0 |
Accretion of discount on investments | ||||||||
1,860 | 2,320 | 2,070 | 1,424 | 769 | 329 | 0 | 0 | 0 |
Non-cash interest expense | ||||||||
355 | 289 | 261 | 179 | 94 | 86 | 0 | 0 | 0 |
Changes in operating assets and liabilities: | ||||||||
Prepaid expenses and other current assets | ||||||||
-874 | -2,655 | 8,374 | 9,914 | 6,204 | 9,037 | 0 | 0 | 0 |
Operating lease, right-of-use-asset | ||||||||
-6,061 | -4,991 | 0 | 0 | 0 | - | - | - | - |
Accounts payable | ||||||||
834 | -1,037 | 5,720 | -2,836 | 3,520 | 4,938 | 0 | 0 | 0 |
Accrued expenses and other current liabilities | ||||||||
5,036 | 6,503 | 5,560 | 5,485 | 1,614 | 4,307 | 0 | 0 | 0 |
Deferred rent | ||||||||
- | - | - | - | - | -15 | 0 | 0 | 0 |
Operating lease liabilities | ||||||||
-4,265 | -2,670 | 0 | 0 | 0 | - | - | - | - |
Net cash used in operating activities | ||||||||
-127,587 | -110,444 | -101,152 | -90,265 | -70,324 | -58,341 | 0 | 0 | 0 |
Cash flows from investing activities: | ||||||||
Purchases of property, plant and equipment | ||||||||
39,344 | 40,657 | 30,662 | 30,909 | 18,286 | 14,952 | 0 | 0 | 0 |
Purchases of investments | ||||||||
211,151 | 319,133 | 332,834 | 259,446 | 222,807 | 160,972 | 0 | 0 | 0 |
Sales and maturities of investments | ||||||||
303,000 | 227,155 | 0 | 0 | 0 | - | - | - | - |
Net cash provided by (used in) investing activities | ||||||||
52,505 | -132,635 | -189,396 | -185,606 | -147,653 | -111,639 | 0 | 0 | 0 |
Cash flows from financing activities: | ||||||||
Proceeds from issuance of convertible preferred stock, net of issuance costs | ||||||||
- | - | - | - | - | 100,986 | 0 | 0 | 0 |
Proceeds from issuance of common stock upon exercise of stock options | ||||||||
2,100 | 2,413 | 1,889 | 1,417 | 859 | 64 | 0 | 0 | 0 |
Net cash provided by financing activities | ||||||||
26,978 | 27,291 | 45,884 | 300,666 | 274,638 | 374,829 | 0 | 0 | 0 |
Net increase (decrease) in cash, cash equivalents and restricted cash | ||||||||
-48,104 | -215,788 | -244,664 | 24,795 | 56,661 | 204,849 | 0 | 0 | 0 |
Supplemental cash flow information: | ||||||||
Cash paid for interest, net of interest capitalized | ||||||||
3,520 | 2,961 | 0 | 0 | 0 | - | - | - | 0 |
Cash paid for leases | ||||||||
7,345 | 5,375 | 0 | 0 | 0 | - | - | - | - |
Supplemental disclosure of non-cash investing and financing information: | ||||||||
Lease assets obtained in exchange for new operating lease liabilities | ||||||||
- | 49,799 | 0 | 0 | 0 | - | - | - | - |
Lease asset derecognized upon lease cancellation | ||||||||
0 | - | - | - | - | - | - | - | - |
Purchases of property, plant and equipment included in accounts payable or accrued expenses | ||||||||
-612 | 3,095 | 6,270 | 5,439 | 5,957 | 1,550 | 0 | 0 | 0 |
Amounts capitalized under build-to-suit lease transaction | ||||||||
- | - | - | - | - | - | 0 | 0 | 0 |