| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||
Net loss | ||||||
-24,097 | -22,854 | -27,679 | - | - | - | |
Net loss | ||||||
- | - | - | -17,366 | -11,564 | -9,712 | |
Adjustments for: | ||||||
Depreciation and amortization | ||||||
357 | 288 | 158 | 118 | 88 | 42 | |
Loss on disposal of property and equipment | ||||||
- | -52 | - | - | - | - | |
Operating lease right-of-use asset amortization | ||||||
263 | - | - | - | - | - | |
Change in fair value of warrant liabilities | ||||||
-8,212 | -4,617 | 6,795 | -1,942 | - | - | |
Non-cash interest expense | ||||||
86 | 337 | - | - | - | 1,372 | |
Non-cash investment expense | ||||||
28 | - | 41 | -30 | - | - | |
Non-cash stock-based compensation | ||||||
3,367 | 2,776 | 1,911 | 1,438 | 1,125 | 264 | |
Non-cash issuance of warrants to a service provider | ||||||
19 | - | - | - | - | - | |
Non-cash issuance of common stock and warrants connected to license agreement | ||||||
- | - | - | 2,780 | - | - | |
Changes in operating assets and liabilities: | ||||||
Prepaid expenses and other current assets | ||||||
1,873 | 1,069 | -260 | 527 | 732 | -109 | |
Other assets | ||||||
-132 | 132 | - | 35 | - | - | |
Accounts payable | ||||||
330 | 180 | 181 | -812 | 1,835 | -21 | |
Accrued expenses and other liabilities | ||||||
358 | -205 | 732 | 497 | - | - | |
Accrued interest payable | ||||||
403 | - | - | - | - | - | |
Operating lease liabilities | ||||||
-160 | - | - | - | - | - | |
Net cash used in operating activities | ||||||
-29,055 | -25,244 | -17,683 | - | - | - | |
Cash flows from investing activities: | ||||||
Accrued expenses and other | ||||||
- | - | - | - | 1,037 | 569 | |
Net cash used in operating activities | ||||||
- | - | - | -15,819 | -8,211 | -7,377 | |
Proceeds from sale of marketable securities | ||||||
38,770 | 34,869 | 22,314 | 8,684 | - | - | |
Purchases of marketable securities | ||||||
15,000 | 58,000 | 34,397 | 14,978 | 8,542 | - | |
Purchases of property and equipment | ||||||
272 | 1,972 | 323 | 213 | 389 | 55 | |
Net cash provided by investing activities | ||||||
23,498 | -25,103 | -12,406 | - | - | - | |
Cash flows from financing activities: | ||||||
Proceeds from term loan and warrants | ||||||
20,000 | - | - | - | - | - | |
Issuance costs in connection with term loan and warrants | ||||||
464 | - | - | - | - | - | |
Net cash provided by investing activities | ||||||
- | - | - | -6,507 | -8,931 | -55 | |
Proceeds from issuance of convertible notes and warrants | ||||||
- | - | - | - | - | 2,975 | |
Payment of financing costs related to convertible notes | ||||||
- | - | - | - | - | 506 | |
Proceeds from issuance of common stock, net of issuance costs | ||||||
- | 37,960 | 39,675 | - | 21,648 | - | |
Proceeds from issuance of common stock in connection with at-the-market offering, net of issuance costs | ||||||
6 | 3,212 | 3,653 | - | - | - | |
Proceeds from issuance of common stock and warrants in connection with private investment in a public entity, net of issuance costs paid of $966 | ||||||
- | - | - | 14,034 | - | - | |
Proceeds from issuance of common stock and warrants in connection with initial public offering, net of issuance costs paid of $2,147 | ||||||
- | - | - | 9,192 | - | - | |
Payment of finance costs related to issuance of common stock | ||||||
- | - | - | - | 1,754 | 18 | |
Proceeds from exercise of warrants | ||||||
- | - | 118 | 5,342 | 25 | 250 | |
Proceeds from exercise of stock options | ||||||
- | - | 92 | 95 | - | - | |
Cash provided by financing activities | ||||||
19,542 | 41,172 | 43,538 | - | - | - | |
Cash provided by (used in) financing activities | ||||||
- | - | - | 28,663 | 19,919 | 2,701 | |
Net increase in cash, cash equivalents and restricted cash | ||||||
13,985 | -9,175 | 13,449 | 6,337 | - | - | |
Net increase in cash and cash equivalents | ||||||
- | - | - | - | 2,777 | -4,731 | |
Supplemental disclosures of cash flow information: | ||||||
Cash paid for taxes | ||||||
30 | 3 | 1 | 1 | - | - | |
Cash paid for interest, net | ||||||
53 | - | - | - | - | - | |
Fair value of warrant liabilities upon private investment in a public entity | ||||||
- | - | - | 8,275 | - | - | |
Issuance of common stock upon conversion of convertible notes and accrued interest | ||||||
- | - | - | - | - | 7,444 | |
Issuance of common stock warrants in connection with initial public offering | ||||||
- | - | - | 218 | - | - | |
Issuance of common stock warrants to brokers in connection with sale of common stock | ||||||
- | - | - | - | 334 | 382 | |
Issuance of common stock warrants to brokers in connection with convertible note financings | ||||||
- | - | - | - | - | 77 | |