| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Grant revenue | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 72 | 280 | 105 | 260 | 331 | 250 |
Operating expenses: | ||||||||||||||||||||
Research and development | ||||||||||||||||||||
5,303 | 5,200 | 5,228 | 7,275 | 5,567 | 4,563 | 5,656 | 5,555 | 3,977 | 3,923 | 3,221 | 3,404 | 2,527 | 2,769 | 2,723 | 2,936 | 5,589 | 2,760 | 2,101 | 1,545 | 1,133 |
General and administrative | ||||||||||||||||||||
2,879 | 2,204 | 2,247 | 2,490 | 2,810 | 2,038 | 2,059 | 2,399 | 2,223 | 2,367 | 1,968 | 1,856 | 1,987 | 1,603 | 1,452 | 1,458 | 1,226 | 1,308 | 1,566 | 1,054 | 1,075 |
Total operating expenses | ||||||||||||||||||||
8,182 | 7,404 | 7,475 | 9,765 | 8,377 | 6,601 | 7,715 | 7,954 | 6,200 | 6,290 | 5,189 | 5,260 | 4,514 | 4,372 | 4,175 | 4,394 | 6,815 | 4,068 | 3,667 | 2,599 | 2,208 |
Loss from operations | ||||||||||||||||||||
-8,182 | -7,404 | -7,475 | -9,765 | -8,377 | -6,601 | -7,715 | -7,954 | -6,200 | -6,290 | -5,189 | -5,260 | -4,514 | -4,372 | -4,175 | -4,322 | -6,535 | -3,963 | -3,407 | -2,268 | -1,958 |
Other income (expense): | ||||||||||||||||||||
Interest income | ||||||||||||||||||||
241 | 297 | 271 | 325 | 361 | 396 | 271 | 198 | 134 | 149 | 141 | 38 | 41 | 31 | 27 | 21 | 17 | - | 10 | - | - |
Interest expense | ||||||||||||||||||||
476 | - | 63 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Change in fair value of warrant liabilities | ||||||||||||||||||||
-239 | -151 | -355 | -4,885 | -2,821 | -780 | 1,336 | -3,971 | -1,202 | -4,679 | 5,780 | 3,667 | 2,027 | - | - | - | - | - | - | - | - |
Interest income | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 5 | - |
Net loss | ||||||||||||||||||||
-8,178 | -7,435 | -6,912 | -4,555 | -5,195 | -5,425 | -8,780 | -3,785 | -4,864 | -1,462 | -10,828 | -8,889 | -6,500 | -2,399 | -4,148 | -4,301 | -6,518 | -3,946 | -3,397 | -2,263 | -1,958 |
Unrealized gain/(loss) on marketable securities | ||||||||||||||||||||
77 | 3 | -20 | -97 | -116 | - | -14 | -22 | - | -9 | -10 | 0 | 3 | 11 | -3 | 4 | -1 | - | 2 | -5 | - |
Comprehensive loss | ||||||||||||||||||||
-8,101 | -7,432 | -6,932 | -4,652 | -5,311 | -5,371 | -8,794 | -3,807 | -4,864 | -1,471 | -10,838 | -8,889 | -6,497 | -2,388 | -4,151 | -4,297 | -6,519 | -3,961 | -3,395 | -2,268 | -1,958 |
Net loss per common share: | ||||||||||||||||||||
Basic | ||||||||||||||||||||
- | - | -0.42 | - | - | - | -0.59 | - | - | - | -0.85 | - | - | - | - | - | - | - | - | - | - |
Diluted | ||||||||||||||||||||
- | - | -0.42 | - | - | - | -0.59 | - | - | - | -0.85 | - | - | - | - | - | - | - | - | - | - |
Weighted-average number of shares outstanding: | ||||||||||||||||||||
Basic | ||||||||||||||||||||
- | - | 16,459 | - | - | - | 14,841 | - | - | - | 12,696 | - | - | - | - | - | - | - | - | - | - |
Diluted | ||||||||||||||||||||
- | - | 16,459 | - | - | - | 14,841 | - | - | - | 12,696 | - | - | - | - | - | - | - | - | - | - |
Net loss per common share - basic and diluted | ||||||||||||||||||||
-0.49 | - | - | -0.28 | -0.32 | - | - | -0.29 | -0.37 | - | - | -0.93 | -0.69 | -0.13 | -0.53 | -0.62 | -1.11 | -0.68 | -0.59 | -0.39 | -0.37 |
Weighted-average number of shares outstanding - basic and diluted | ||||||||||||||||||||
16,523 | - | - | 16,443 | 16,436 | - | - | 13,179 | 12,991 | - | - | 9,517 | 9,416 | 8,465 | 7,759 | 6,923 | 5,877 | 5,802 | 5,796 | 5,796 | 5,336 |