| Dec'19 | Dec'18 | Dec'17 | Dec'16 | |||
|---|---|---|---|---|---|---|
Operating expenses: | ||||||
Research and development | ||||||
24,632 | 15,948 | 14,331 | 11,856 | |||
General and administrative | ||||||
8,273 | 13,719 | 9,105 | 6,054 | |||
Total operating expenses | ||||||
32,905 | 29,667 | 23,436 | 17,910 | |||
Loss from operations | ||||||
-32,905 | -29,667 | -23,436 | -17,910 | |||
Other expense | ||||||
16 | -56 | 75 | 38 | |||
Interest income | ||||||
1,660 | 1,712 | 341 | 7 | |||
Interest expense | ||||||
1,767 | 1,432 | 797 | 6,512 | |||
Net loss and comprehensive loss | ||||||
-32,996 | -29,443 | -23,817 | -24,377 | |||
Net loss per share — basic and diluted | ||||||
-1.77 | -1.59 | -8.04 | -25.01 | |||
Weighted average common shares outstanding — basic and diluted | ||||||
18,600 | 18,556 | 2,962 | 974 | |||