| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Sep'15 | Jun'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Grant and collaboration revenue | ||||||||||||||||||
0 | 6,654 | 0 | 13 | 10 | 903 | 0 | 0 | 0 | - | 27 | 26 | - | - | - | - | - | - | - |
Grant and collaboration revenue | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 137 | - | 1,048 | 2,017 | 2,088 | 1,607 | 1,236 |
Operating expenses: | ||||||||||||||||||
Research and development | ||||||||||||||||||
14,724 | 15,152 | 8,104 | 12,134 | 7,353 | 10,256 | 11,885 | 14,407 | 11,139 | 13,623 | 9,504 | 10,994 | 11,044 | 11,033 | 6,021 | 6,000 | 6,648 | 5,483 | 5,314 |
General and administrative | ||||||||||||||||||
4,098 | 4,072 | 3,690 | 4,114 | 4,513 | 5,146 | 4,056 | 4,362 | 4,674 | 5,671 | 4,377 | 4,903 | 3,875 | 5,757 | 2,495 | 2,418 | 2,381 | 2,195 | 2,238 |
Total operating expenses | ||||||||||||||||||
18,822 | 19,224 | 11,794 | 16,248 | 11,866 | 15,402 | 15,941 | 18,769 | 15,813 | 19,294 | 13,881 | 15,897 | 14,919 | 16,790 | 8,516 | 8,418 | 9,029 | 7,678 | 7,552 |
Loss from operations | ||||||||||||||||||
-18,822 | -12,570 | -11,794 | -16,235 | -11,856 | -14,499 | -15,941 | -18,769 | -15,813 | -19,277 | -13,854 | -15,871 | -14,782 | -13,860 | -7,468 | -6,401 | -6,941 | -6,071 | -6,316 |
Investment income | ||||||||||||||||||
240 | 127 | 184 | 246 | 277 | 221 | 295 | 246 | 288 | 238 | 165 | 101 | 113 | 113 | 98 | 10 | 13 | 25 | 62 |
Loss on extinguishment of debt | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | -673 | - | - | - | 0 | - | - | - | - |
Foreign currency transaction (loss), net | ||||||||||||||||||
82 | -14 | 7 | -10 | -30 | 23 | 26 | 84 | -13 | -10 | -30 | 82 | -165 | -96 | -51 | -158 | -220 | 668 | -246 |
Interest expense | ||||||||||||||||||
273 | 335 | 388 | 400 | 396 | 395 | 384 | 365 | 350 | 359 | 268 | 279 | 300 | 322 | 311 | 310 | 310 | 334 | 330 |
Change in fair value of warrant liabilities | ||||||||||||||||||
846 | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Other (expense), net | ||||||||||||||||||
-1 | -1,239 | -3 | 5 | -69 | -1 | 3 | 8 | 0 | - | -16 | 0 | - | 82 | 4 | -64 | -18 | -13 | - |
Net loss | ||||||||||||||||||
-19,620 | -14,888 | -11,994 | -16,394 | -12,074 | -14,651 | -16,001 | -18,796 | -15,888 | -19,544 | -14,676 | -15,967 | -15,134 | -14,083 | -7,728 | -6,923 | -7,476 | -5,725 | -6,867 |
Stock‑based compensation expense | ||||||||||||||||||
1,409 | - | - | - | 1,180 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Temporary Equity, Accretion to Redemption Value, Adjustment | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 2,210 | 2,356 | - | - |
Accretion of redeemable convertible preferred stock | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1,836 | 1,562 |
Net Income (Loss) Available to Common Stockholders, Basic | ||||||||||||||||||
- | - | -11,994 | -16,394 | - | - | -16,001 | -18,796 | -15,888 | - | - | - | -15,134 | -14,083 | -7,728 | -9,133 | -9,832 | -7,561 | -8,429 |
Other expense, net | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 37 |
Net loss | ||||||||||||||||||
-19,620 | -14,888 | -11,994 | -16,394 | -12,074 | -14,651 | -16,001 | -18,796 | -15,888 | -19,544 | -14,676 | -15,967 | -15,134 | -14,083 | -7,728 | -6,923 | -7,476 | -5,725 | -6,867 |
Other comprehensive loss: | ||||||||||||||||||
Foreign currency translation adjustment | ||||||||||||||||||
-60 | 10 | -5 | 7 | 22 | -40 | -42 | -90 | 19 | -1 | -1 | -43 | 123 | 88 | 15 | 170 | 231 | -800 | 245 |
Unrealized gain on securities | ||||||||||||||||||
0 | 0 | -3 | 1 | 2 | 0 | 1 | 12 | 3 | -10 | 5 | 10 | 15 | -52 | 16 | 0 | 0 | 0 | - |
Total comprehensive loss | ||||||||||||||||||
-19,680 | -14,878 | -12,002 | -16,386 | -12,050 | -14,691 | -16,042 | -18,874 | -15,866 | -19,555 | -14,672 | -16,000 | -14,996 | -14,047 | -7,697 | -6,753 | -7,245 | -6,525 | -6,622 |
Net loss per share: | ||||||||||||||||||
Net loss per share attributable to common stockholders—basic and diluted (in dollars per share) | ||||||||||||||||||
-0.21 | -0.28 | -0.26 | -0.37 | -0.31 | -0.66 | -0.71 | -0.84 | -0.71 | -0.87 | -0.66 | -0.85 | -0.82 | 3.81 | -0.43 | -2.75 | -4.52 | -3.50 | -3.93 |
Weighted average common shares outstanding: | ||||||||||||||||||
Basic and diluted (in shares) | ||||||||||||||||||
94,723 | 52,483 | 46,407 | 44,855 | 38,447 | 22,452 | 22,403 | 22,355 | 22,345 | 22,329 | 22,082 | 18,814 | 18,474 | 18,370 | 18,108 | 3,322 | 2,175 | 2,159 | 2,147 |