| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
Revenue: | ||||||
Total revenues | ||||||
1,517 | 1,517 | 2,108 | 1,220 | - | - | |
Total revenues | ||||||
1,517 | 1,517 | 2,108 | 1,220 | - | - | |
License fees | ||||||
- | - | - | - | 627 | - | |
Total revenues | ||||||
- | - | - | - | 627 | - | |
Operating expenses: | ||||||
Research and development | ||||||
42,994 | 60,106 | 48,201 | 31,665 | 9,549 | 10,175 | |
General and administrative | ||||||
16,062 | 17,287 | 15,861 | 13,321 | 11,591 | 11,157 | |
Total operating expenses | ||||||
59,056 | 77,393 | 64,062 | 44,986 | 21,140 | 21,332 | |
Loss from operations | ||||||
-57,539 | -75,876 | -61,954 | -43,766 | -20,513 | -21,332 | |
Other (expense) income: | ||||||
Interest income (expense), net | ||||||
1,571 | 1,942 | 1,421 | 956 | -1,414 | -289 | |
Change in fair value of common stock warrant liability | ||||||
- | - | - | 1,703 | 2,155 | -1,789 | |
Other (expense) income | ||||||
-79 | -27 | -269 | 41 | -37 | 4 | |
Total other (expense) income | ||||||
1,492 | 1,915 | 1,152 | -706 | -3,606 | 1,504 | |
Net loss | ||||||
-56,047 | -73,961 | -60,802 | -44,472 | -24,119 | -19,828 | |
Other comprehensive income (loss): | ||||||
Net loss attributable to common stockholders | ||||||
-56,047 | -73,961 | -60,802 | -47,070 | -103,845 | -26,357 | |
Net loss per share attributable to common stockholders—basic and diluted | ||||||
-1.84 | -2.92 | -2.90 | -3.22 | -1,519.27 | -453.02 | |
Weighted-average number of common shares used to compute net loss per share attributable to common stockholders—basic and diluted | ||||||
30,490 | 25,371 | 20,997 | 14,619 | 68 | 58 | |