| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenue: | ||||||||||||||||||||
Total revenues | ||||||||||||||||||||
379 | 380 | 379 | 379 | 379 | 380 | 379 | 379 | 379 | 1,193 | 305 | 305 | 305 | - | - | - | - | - | - | - | - |
Total revenues | ||||||||||||||||||||
379 | 380 | 379 | 379 | 379 | 380 | 379 | 379 | 379 | 1,193 | 305 | 305 | 305 | - | - | - | - | - | - | - | - |
License fees | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | 305 | 305 | 305 | - | 305 | 17 | - |
Total revenues | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | 305 | 305 | 305 | - | 305 | 17 | - |
Operating expenses: | ||||||||||||||||||||
Research and development | ||||||||||||||||||||
9,562 | 9,502 | 9,923 | 12,290 | 11,279 | 15,821 | 14,095 | 14,851 | 15,339 | 16,599 | 12,188 | 9,862 | 9,552 | 8,474 | 12,274 | 6,131 | 4,786 | 2,587 | 2,968 | 2,271 | 1,723 |
General and administrative | ||||||||||||||||||||
5,917 | 5,083 | 3,605 | 3,463 | 3,911 | 3,892 | 4,125 | 4,479 | 4,791 | 4,083 | 3,563 | 4,285 | 3,930 | 2,972 | 3,269 | 2,808 | 4,272 | 2,397 | 3,195 | 3,288 | 2,711 |
Total operating expenses | ||||||||||||||||||||
15,479 | 14,585 | 13,528 | 15,753 | 15,190 | 19,713 | 18,220 | 19,330 | 20,130 | 20,682 | 15,751 | 14,147 | 13,482 | 11,446 | 15,543 | 8,939 | 9,058 | 4,984 | 6,163 | 5,559 | 4,434 |
Loss from operations | ||||||||||||||||||||
-15,100 | -14,205 | -13,149 | -15,374 | -14,811 | -19,333 | -17,841 | -18,951 | -19,751 | -19,489 | -15,446 | -13,842 | -13,177 | -11,141 | -15,238 | -8,634 | -8,753 | -4,679 | -5,858 | -5,542 | -4,434 |
Other (expense) income: | ||||||||||||||||||||
Interest expense | ||||||||||||||||||||
449 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Interest income | ||||||||||||||||||||
333 | - | - | - | 452 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Interest income (expense), net | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 268 | 268 | 276 | 144 | -524 | -229 | -322 | -339 |
Change in fair value of common stock warrant liability | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 1,703 | 70 | 1,607 | 346 | 132 |
Other (expense) income | ||||||||||||||||||||
-20 | -17 | -76 | -43 | 57 | - | - | - | - | - | - | - | - | 58 | 1 | 0 | -18 | 10 | -37 | -4 | -6 |
Total other (expense) income | ||||||||||||||||||||
-136 | 205 | 320 | 458 | 509 | 496 | 503 | 563 | 353 | 385 | 358 | 203 | 206 | 326 | 269 | 276 | -1,577 | -584 | -1,873 | -672 | -477 |
Net loss | ||||||||||||||||||||
-15,236 | -14,000 | -12,829 | -14,916 | -14,302 | -18,837 | -17,338 | -18,388 | -19,398 | -19,104 | -15,088 | -13,639 | -12,971 | -10,815 | -14,969 | -8,358 | -10,330 | -5,263 | -7,731 | -6,214 | -4,911 |
Other comprehensive income (loss): | ||||||||||||||||||||
Unrealized gain on marketable securities | ||||||||||||||||||||
48 | - | -33 | 50 | 33 | - | - | - | - | - | - | - | - | - | -92 | -36 | 200 | - | - | -11 | 3 |
Comprehensive loss | ||||||||||||||||||||
-15,188 | - | -12,862 | -14,866 | -14,269 | - | - | - | - | - | - | - | - | - | -15,061 | -8,394 | -10,130 | - | - | -6,225 | -4,908 |
Net loss attributable to common stockholders | ||||||||||||||||||||
-19,142 | -14,000 | -12,829 | -14,916 | -14,302 | - | - | - | - | - | - | - | - | -10,815 | -14,969 | -8,358 | -12,928 | -8,779 | -56,656 | -26,338 | -12,072 |
Net loss per share attributable to common stockholders—basic and diluted | ||||||||||||||||||||
-0.56 | -0.44 | -0.41 | -0.47 | -0.53 | 0.70 | 0.68 | 0.74 | 0.79 | -0.80 | -0.84 | -0.47 | -2.85 | 0.94 | -0.84 | -0.47 | -2.85 | -81.60 | -790.85 | -440.52 | -206.30 |
Weighted-average number of common shares used to compute net loss per share attributable to common stockholders—basic and diluted | ||||||||||||||||||||
34,328 | 31,640 | 31,630 | 31,605 | 27,023 | 26,804 | 25,471 | 24,705 | 24,478 | 23,943 | 22,239 | 19,497 | 18,231 | 18,268 | 17,899 | 17,769 | 4,541 | 83 | 71 | 59 | 58 |