| Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 | Dec'13 | Sep'13 | Jun'13 | Mar'13 | Dec'12 | Sep'12 | Jun'12 | Mar'12 | Dec'11 | Sep'11 | Jun'11 | Mar'11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Operating activities | |||||||||||||||||||||||||||||
Net loss | |||||||||||||||||||||||||||||
-2,402 | -1,584 | -1,263 | -12,106 | -12,395 | -11,703 | -10,686 | -9,962 | -9,906 | -10,498 | -12,648 | -12,797 | -14,798 | -14,711 | -12,150 | -12,141 | -11,210 | -10,898 | -11,898 | -11,025 | -9,577 | -10,342 | -9,186 | -8,630 | -9,227 | -9,321 | -8,724 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash provided by (used in) operating activities: | |||||||||||||||||||||||||||||
Depreciation | |||||||||||||||||||||||||||||
712 | 749 | 757 | 728 | 732 | 727 | 741 | 769 | 790 | 848 | 1,098 | 1,438 | 1,784 | 2,092 | 2,239 | 2,362 | 2,526 | 2,704 | 2,847 | 2,902 | 2,910 | 2,860 | 2,789 | 2,725 | 2,662 | 2,618 | 2,629 | 0 | 0 | 0 |
Accretion (amortization) of premium on available-for-sale securities | |||||||||||||||||||||||||||||
33 | 3 | -29 | -59 | -101 | -131 | -152 | -162 | -146 | -147 | -148 | -159 | -201 | -213 | -220 | -238 | -255 | -262 | -258 | -235 | -188 | -167 | -181 | -234 | -325 | -451 | -550 | 0 | 0 | 0 |
Amortization of leasehold incentive obligation | |||||||||||||||||||||||||||||
219 | 219 | 219 | 219 | 220 | 220 | 220 | 219 | 219 | 219 | 347 | 540 | 731 | 923 | 987 | 987 | 988 | 987 | 987 | 987 | 987 | 988 | 987 | 987 | 987 | 987 | 987 | 0 | 0 | 0 |
Stock-based compensation for employees and non-employee directors | |||||||||||||||||||||||||||||
2,477 | 2,892 | 3,149 | 3,469 | 3,812 | 4,056 | 4,412 | 4,680 | 4,906 | 4,996 | 5,230 | 5,470 | 5,866 | 6,153 | 6,142 | 5,696 | 5,019 | 4,452 | 4,005 | 4,056 | 4,115 | 4,290 | 4,464 | 4,400 | 4,451 | 4,575 | 4,670 | 0 | 0 | 0 |
Amortization of leasehold incentive obligation | |||||||||||||||||||||||||||||
219 | 219 | 219 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | 987 | 987 | 988 | 987 | 987 | 987 | 987 | 987 | 0 | 0 | 0 |
Stock-based compensation for employees and non-employee directors | |||||||||||||||||||||||||||||
2,477 | 2,892 | 3,149 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | 4,056 | 4,115 | 4,290 | 4,464 | 4,400 | 4,451 | 4,575 | 4,670 | 0 | 0 | 0 |
Stock-based compensation for non-employees | |||||||||||||||||||||||||||||
23 | 21 | 23 | 6 | 20 | 26 | 27 | 49 | 50 | 46 | 40 | 32 | 19 | 23 | 39 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Stock-based compensation for non-employees | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | - | 28 | 31 | 101 | 137 | 0 | 0 | 0 |
Change in operating assets and liabilities: | |||||||||||||||||||||||||||||
Accounts receivable | |||||||||||||||||||||||||||||
-2,010 | -5,050 | 1,778 | 459 | -242 | 224 | 2,159 | 2,070 | 1,506 | 3,954 | 917 | 343 | -492 | -1,700 | 150 | 1,156 | 739 | 1,394 | -576 | -895 | -577 | -337 | 268 | 1,240 | 584 | 907 | 885 | 0 | 0 | 0 |
Inventories | |||||||||||||||||||||||||||||
-322 | -711 | -756 | -109 | -140 | -148 | -279 | -515 | -445 | -265 | 877 | 906 | 1,953 | 1,884 | 1,361 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Other current assets | |||||||||||||||||||||||||||||
-736 | -757 | -516 | -196 | 230 | 199 | -20 | -196 | -222 | -183 | -387 | -29 | 85 | 241 | 438 | 24 | -28 | -17 | -235 | 164 | 128 | -176 | 199 | 0 | 0 | 0 | - | - | - | - |
Other assets | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 |
Accounts payable, accrued expenses and other current liabilities | |||||||||||||||||||||||||||||
-705 | -826 | -613 | -1,313 | -558 | -178 | -61 | -180 | 92 | 601 | 255 | 502 | -419 | -418 | -2,071 | -732 | -543 | -1,232 | 614 | 77 | 299 | 974 | 592 | 451 | 447 | 631 | -422 | 0 | 0 | 0 |
Deferred revenues | |||||||||||||||||||||||||||||
- | - | - | - | - | - | -3,497 | -4,145 | -2,548 | -2,183 | -2,180 | -2,799 | -2,045 | -3,903 | -4,862 | -6,019 | -6,218 | -5,441 | -5,027 | -5,068 | -7,949 | -8,300 | -9,702 | -10,016 | -10,580 | -10,907 | -12,410 | 0 | 0 | 0 |
Deferred rent | |||||||||||||||||||||||||||||
671 | 679 | 678 | -72 | -573 | -578 | -559 | -299 | 438 | 1,293 | 1,575 | 1,388 | 723 | -59 | -268 | -246 | -388 | -265 | -183 | -312 | -66 | -86 | -105 | 85 | 66 | 46 | 26 | 0 | 0 | 0 |
Net cash used in operating activities | |||||||||||||||||||||||||||||
0 | 0 | - | - | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Deferred rent | |||||||||||||||||||||||||||||
671 | 679 | 678 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | -312 | -66 | -86 | -105 | 85 | 66 | 46 | 26 | 0 | 0 | 0 |
Net cash used in operating activities | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | 0 | 0 | -8,475 | - | -8,367 | -10,946 | -11,958 | -13,647 | -14,587 | -12,715 | -13,376 | -9,732 | -9,224 | -10,683 | -10,929 | -12,415 | -12,953 | -12,799 | -13,127 | -14,314 | 0 | 0 | 0 |
Investing activities | |||||||||||||||||||||||||||||
Purchases of property and equipment | |||||||||||||||||||||||||||||
323 | 439 | 558 | 488 | 424 | 249 | 138 | 159 | 154 | 361 | 690 | 671 | 698 | 685 | 328 | 394 | 497 | 447 | 623 | 552 | 496 | 1,213 | 1,470 | 1,947 | 2,271 | 2,082 | 3,061 | 0 | 0 | 0 |
Purchases of available-for-sale securities | |||||||||||||||||||||||||||||
15,259 | 12,131 | 11,635 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | 20,885 | 25,907 | 28,717 | 30,462 | 30,408 | 29,403 | 38,606 | 24,021 | 34,242 | 0 | 0 | 0 |
Maturities of available-for-sale securities | |||||||||||||||||||||||||||||
10,801 | 9,601 | 10,751 | 13,600 | 16,850 | 20,900 | 18,750 | 23,551 | 24,401 | 18,901 | 22,530 | 20,204 | 18,854 | 20,854 | 18,815 | 13,490 | 9,940 | 17,787 | 25,295 | 31,170 | 32,969 | 43,884 | 43,010 | 43,135 | 50,536 | 32,724 | 44,904 | 0 | 0 | 0 |
Net cash (used in) provided by investing activities | |||||||||||||||||||||||||||||
0 | 0 | - | - | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net cash provided by investing activities | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | 0 | 0 | 2,432 | - | 6,948 | 5,871 | -1,870 | -3,552 | -3,557 | -3,308 | 3,002 | 3,787 | 4,711 | 3,756 | 12,209 | 11,132 | 11,785 | 9,659 | 6,621 | 7,601 | 0 | 0 | 0 |
Financing activities | |||||||||||||||||||||||||||||
Proceeds from issuance of common stock, net of issuance costs | |||||||||||||||||||||||||||||
153 | 141 | 2,053 | 2,328 | 2,781 | 2,796 | 1,246 | 1,550 | 2,523 | 2,992 | 3,361 | 3,216 | 3,076 | 6,353 | 9,959 | 10,699 | 9,497 | 5,742 | 1,719 | 801 | 877 | 869 | 746 | 784 | 909 | 1,083 | 1,419 | 0 | 0 | 0 |
Net cash provided by financing activities | |||||||||||||||||||||||||||||
0 | 0 | - | - | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net cash provided by financing activities | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | 0 | 0 | 2,992 | - | 3,216 | 3,076 | 6,353 | 9,959 | 10,699 | 9,497 | 5,742 | 1,719 | 801 | 877 | 869 | 746 | 784 | 909 | 1,083 | 1,419 | 0 | 0 | 0 |
Net change in cash and cash equivalents | |||||||||||||||||||||||||||||
- | - | - | - | - | - | -1,231 | -2,404 | 847 | -3,051 | 857 | 1,797 | -1,999 | -7,475 | -7,240 | -7,445 | -6,526 | -4,632 | -4,226 | -3,712 | -6,050 | 2,149 | -537 | -384 | -2,231 | -5,423 | -5,294 | 0 | 0 | 0 |
Net change in cash and cash equivalents | |||||||||||||||||||||||||||||
0 | 0 | - | - | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Supplemental disclosure of cash flow information: | |||||||||||||||||||||||||||||
Purchases of inventories included in accounts payable, accrued expenses and other current liabilities at year-end | |||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities at period end | |||||||||||||||||||||||||||||
-45 | -114 | 28 | 15 | 26 | 142 | 0 | -21 | 47 | -52 | 0 | 114 | 93 | 35 | 93 | -73 | -64 | 38 | 0 | 0 | 0 | 0 | - | - | -92 | 660 | 204 | 0 | 0 | 0 |