| Dec'18 | Dec'17 | Dec'16 | Dec'15 | |||
|---|---|---|---|---|---|---|
Operating activities | ||||||
Net loss | ||||||
-73,471 | -50,545 | -21,162 | - | |||
Net loss | ||||||
- | - | - | -11,294 | |||
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Depreciation | ||||||
157 | 120 | 67 | 32 | |||
Amortization of debt discount and issuance costs | ||||||
259 | 729 | - | - | |||
Stock-based compensation | ||||||
4,700 | 2,112 | 413 | 111 | |||
Fair value adjustment of success payment liability | ||||||
-3,282 | 2,023 | 568 | 694 | |||
Fair value adjustment of contingent consideration | ||||||
6,300 | 2,989 | - | - | |||
Non-cash interest expense | ||||||
476 | 34 | - | - | |||
Non-cash expense in connection with conversion of notes | ||||||
- | - | - | 390 | |||
Loss on disposal of property and equipment | ||||||
-3 | -5 | - | - | |||
Changes in assets and liabilities: | ||||||
Prepaid expenses and other current assets | ||||||
-997 | 1,349 | 346 | 597 | |||
Restricted cash | ||||||
- | - | - | 35 | |||
Accounts payable and other accrued liabilities | ||||||
2,168 | 2,870 | 2,851 | 720 | |||
Net cash used in operating activities | ||||||
-61,693 | -41,012 | -17,609 | - | |||
Investing activities | ||||||
Net cash used in operating activities | ||||||
- | - | - | -9,979 | |||
Investment in property and equipment | ||||||
39 | 274 | 238 | 88 | |||
Proceeds from sale of property and equipment | ||||||
- | 8 | - | - | |||
Acquisition of Creabilis, net of cash received | ||||||
- | - | 6,821 | - | |||
Net cash used in investing activities | ||||||
-39 | -266 | -7,059 | - | |||
Financing activities | ||||||
Net cash used in investing activities | ||||||
- | - | - | -88 | |||
Proceeds from issuance of common stock, net of issuance costs, early exercise liability and repurchase of unvested early exercise stock options | ||||||
5,387 | 188 | 831 | 185 | |||
Repurchase of unvested early exercise stock options | ||||||
- | - | - | 3,240 | |||
Net proceeds from issuance of long-term debt | ||||||
29,866 | - | - | - | |||
Proceeds from issuance of common stock upon ESPP purchase | ||||||
707 | - | - | - | |||
Proceeds from issuance of convertible promissory notes | ||||||
- | 3,906 | - | 13,000 | |||
Conversion of convertible promissory notes | ||||||
- | - | - | 13,825 | |||
Repayment of convertible promissory notes | ||||||
- | - | - | 67 | |||
Proceeds from initial public offering, net of issuance costs | ||||||
- | 66,378 | - | - | |||
Net cash provided by financing activities | ||||||
35,960 | 106,778 | 28,843 | - | |||
Net cash (used in) provided by financing activities | ||||||
- | - | - | 14,620 | |||
Effect of exchange rate changes on cash | ||||||
-169 | -52 | 28 | - | |||
Net decrease in cash, cash equivalents and restricted cash | ||||||
-25,941 | 65,448 | 4,203 | - | |||
Net increase in cash and cash equivalents | ||||||
- | - | - | 4,553 | |||
Supplemental Disclosure of Cash Flow Information: | ||||||
Common stock issued for acquisition | ||||||
- | - | 11,155 | - | |||
Fair value of contingent consideration for acquisition | ||||||
- | - | 24,110 | - | |||
Fair value of in-process research and development intangible asset | ||||||
- | - | 42,254 | - | |||
Fair value of goodwill | ||||||
- | - | 9,788 | - | |||
Fair value of deferred tax liability | ||||||
- | - | 9,412 | - | |||
Preferred stock issued upon conversion of notes payable | ||||||
- | 3,940 | - | 13,467 | |||
Preferred stock issued relating to beneficial conversion feature of notes payable | ||||||
- | 729 | - | - | |||
Fair value of contingent consideration settled in common stock | ||||||
- | 4,199 | - | - | |||
Shares issued for services | ||||||
- | 126 | 55 | - | |||
Interest paid in cash | ||||||
982 | - | - | - | |||
Interest paid in cash | ||||||
- | - | - | 157 | |||
Series A-3 Preferred Stock [Member] | ||||||
Net proceeds from issuance of preferred stock | ||||||
- | - | 28,012 | - | |||
Series B Preferred Stock [Member] | ||||||
Net proceeds from issuance of preferred stock | ||||||
- | 36,306 | - | - | |||