| Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 |
|---|---|---|---|---|---|---|---|---|---|---|
Operating activities | ||||||||||
Net loss | ||||||||||
-47,951 | -60,775 | -72,750 | -73,471 | 0 | 0 | 0 | - | - | - | - |
Net loss | ||||||||||
- | - | - | - | - | - | - | - | - | - | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||
Depreciation | ||||||||||
152 | 155 | 157 | 157 | 157 | 145 | 133 | 120 | 0 | 0 | 0 |
Amortization of debt discount and issuance costs | ||||||||||
0 | 0 | 0 | - | - | - | - | - | - | - | - |
Amortization of debt discount | ||||||||||
- | - | - | - | - | - | - | - | - | 0 | 0 |
Stock-based compensation | ||||||||||
5,119 | 5,208 | 5,332 | 4,700 | 4,448 | 3,695 | 2,880 | 2,112 | 0 | 0 | 0 |
Fair value adjustment of success payment liability | ||||||||||
- | - | - | -3,282 | -5,106 | -2,454 | -195 | 2,023 | 0 | 0 | 0 |
Fair value adjustment of contingent consideration | ||||||||||
-24,500 | 8,300 | 9,400 | 6,300 | 1,399 | 3,199 | 3,099 | 2,989 | 0 | 0 | 0 |
Non-cash interest expense | ||||||||||
0 | 0 | 0 | - | - | - | - | - | - | - | - |
Non-cash interest expense | ||||||||||
- | - | - | - | - | - | - | - | - | - | 0 |
Loss on disposal of property and equipment | ||||||||||
0 | 0 | 0 | - | - | - | - | - | - | - | - |
Impairment of operating lease – right-of-use asset | ||||||||||
0 | 0 | 0 | - | - | - | - | - | - | - | - |
Changes in assets and liabilities: | ||||||||||
Prepaid expenses and other current assets | ||||||||||
5,279 | -1,350 | -874 | -997 | 858 | -910 | 595 | 1,349 | 0 | 0 | 0 |
Accounts payable and other accrued liabilities | ||||||||||
-9,136 | -7,685 | -2,103 | 2,168 | 4,647 | 5,740 | 2,101 | 2,870 | 0 | 0 | 0 |
Net cash used in operating activities | ||||||||||
-54,629 | -52,674 | -60,007 | -61,693 | 0 | 0 | 0 | - | - | - | - |
Investing activities | ||||||||||
Net cash used in operating activities | ||||||||||
- | - | - | - | - | - | - | - | - | - | 0 |
Investment in property and equipment | ||||||||||
10 | 26 | 39 | 39 | 137 | 217 | 228 | 274 | 0 | 0 | 0 |
Net cash used in investing activities | ||||||||||
-10 | -26 | -39 | -39 | 0 | 0 | 0 | - | - | - | - |
Financing activities | ||||||||||
Net cash used in investing activities | ||||||||||
- | - | - | - | - | - | - | - | - | - | 0 |
Proceeds from issuance of common stock, net of issuance costs, early exercise liability and repurchase of unvested early exercise stock options | ||||||||||
21,810 | 26,865 | 26,847 | 5,387 | 5,444 | 371 | 164 | 188 | 0 | 0 | 0 |
Debt issuance costs related to long-term debt | ||||||||||
- | - | 0 | - | - | - | - | - | - | - | - |
Proceeds from issuance of convertible promissory notes | ||||||||||
- | - | - | - | - | - | - | 3,906 | 0 | 0 | 0 |
Net cash provided by financing activities | ||||||||||
2,171 | 27,164 | 57,404 | 35,960 | 0 | 0 | 0 | - | - | - | - |
Net cash (used in) provided by financing activities | ||||||||||
- | - | - | - | - | - | - | - | - | - | 0 |
Effect of exchange rate changes on cash | ||||||||||
-143 | -144 | -202 | -169 | 19 | 37 | 77 | -52 | 0 | 0 | 0 |
Net decrease in cash, cash equivalents and restricted cash | ||||||||||
-52,611 | -25,680 | -2,844 | -25,941 | -24,626 | 43,168 | 53,242 | 65,448 | 0 | 0 | 0 |
Supplemental Disclosure of Cash Flow Information: | ||||||||||
Right-of-use asset obtained in exchange for lease liability | ||||||||||
0 | 0 | 0 | - | - | - | - | - | - | - | - |
Warrants issued | ||||||||||
0 | 0 | 0 | - | - | - | - | - | - | - | - |