| Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 |
|---|---|---|---|---|---|---|---|
License revenue | |||||||
- | - | - | - | - | 5,000 | - | - |
Operating expenses: | |||||||
Research and development | |||||||
10,710 | 6,186 | 3,538 | 9,862 | 24,708 | 10,279 | 13,523 | 8,660 |
General and administrative | |||||||
4,429 | 5,732 | 6,768 | 3,626 | 5,332 | 4,511 | 5,685 | 4,635 |
Total operating expenses | |||||||
15,139 | 11,918 | 10,306 | 13,488 | 30,040 | 14,790 | 19,208 | 13,295 |
Other income (expense): | |||||||
Interest expense | |||||||
684 | 207 | 373 | 690 | 726 | 1,308 | 1,988 | 895 |
Interest income | |||||||
333 | 238 | 37 | 22 | 51 | 0 | 108 | - |
Gain on revaluation of warrant liability | |||||||
8,690 | 3,307 | -330 | 0 | 49 | 689 | - | - |
Loss on early extinguishment of debt | |||||||
- | - | -180 | 0 | 0 | - | - | - |
Other income (expense), net | |||||||
22 | -48 | -12 | -41 | -46 | -240 | -106 | -11 |
Total other income (expense) | |||||||
8,361 | 3,290 | -858 | -709 | -672 | -859 | -1,986 | -906 |
Net loss before income taxes | |||||||
- | - | - | - | - | -10,649 | -21,194 | -14,201 |
Income tax expense | |||||||
- | - | - | - | - | 500 | - | - |
Net loss | |||||||
-6,778 | -8,628 | -11,164 | -14,197 | -30,712 | -11,149 | -21,194 | -14,201 |
Basic and diluted loss per share (in dollars per share) | |||||||
-0.23 | -0.29 | -0.49 | -0.84 | -1.85 | -1.39 | -6.94 | -6.05 |
Weighted average number of outstanding shares – basic and diluted (in shares) | |||||||
30,115 | 30,111 | 23,002 | 16,881 | 16,586 | 8,029 | 3,054 | 2,345 |
Other comprehensive loss: | |||||||
Foreign currency translation adjustment | |||||||
- | - | - | - | - | 145 | 131 | 14 |
Unrealized income on securities available-for-sale | |||||||
3 | -2 | - | 0 | 1 | -1 | - | - |
Total other comprehensive loss | |||||||
-6,775 | -8,630 | -11,164 | -14,197 | -30,711 | -11,005 | -21,063 | -14,187 |