| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||||||||
Net loss | ||||||||||||
-79,111 | -60,925 | -46,538 | -39,284 | -36,090 | -41,662 | -44,931 | -44,312 | -44,119 | -39,886 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||||
Depreciation and amortization | ||||||||||||
755 | 750 | 1,000 | 592 | 498 | 409 | 369 | 382 | 371 | 363 | 0 | 0 | 0 |
Non-cash lease cost | ||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - |
Change in fair value of derivative liabilities | ||||||||||||
- | - | - | - | - | - | - | - | - | 1,541 | 0 | 0 | 0 |
Share-based compensation | ||||||||||||
3,953 | 3,776 | 3,616 | 3,340 | 3,068 | 2,749 | 2,353 | 2,579 | 1,979 | 1,427 | 0 | 0 | 0 |
Realized (gain) loss on investments | ||||||||||||
- | 1 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Unrealized foreign currency transaction (gain) loss | ||||||||||||
-530 | 18 | -300 | -88 | -270 | -373 | 0 | 0 | 0 | - | - | - | - |
Accretion of discount on marketable securities | ||||||||||||
448 | 750 | 988 | 1,120 | 981 | 671 | 0 | 0 | 0 | - | - | - | - |
Changes in operating assets and liabilities: | ||||||||||||
Other receivables | ||||||||||||
2,268 | 7,384 | 4,681 | 1,279 | -763 | -635 | -205 | 566 | 1,105 | 707 | 0 | 0 | 0 |
Prepaid expenses and other current assets | ||||||||||||
-2,242 | -2,654 | 2,401 | 4,904 | 6,549 | 5,497 | 73 | 283 | 102 | 575 | 0 | 0 | 0 |
Tax incentive receivables | ||||||||||||
-128 | -299 | 529 | -963 | -753 | -770 | 25 | 1,619 | 1,697 | 1,811 | 0 | 0 | 0 |
Other assets | ||||||||||||
4,569 | 2,912 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Accounts payable | ||||||||||||
8,396 | 564 | 1,131 | 305 | -455 | 84 | 373 | -516 | -38 | 2,349 | 0 | 0 | 0 |
Accrued expenses and other current liabilities | ||||||||||||
7,595 | 13,610 | 3,952 | 367 | 46 | 3,575 | 2,676 | 366 | 1,046 | 1,315 | 0 | 0 | 0 |
Deferred rent | ||||||||||||
- | - | - | - | - | 554 | -124 | -125 | 333 | -128 | 0 | 0 | 0 |
Other long-term liabilities | ||||||||||||
-107 | -52 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Advance payments from collaborator | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Net cash used in operating activities | ||||||||||||
-62,425 | -50,020 | -46,162 | -42,017 | -38,588 | -39,625 | 0 | 0 | 0 | - | - | - | - |
Cash flows from investing activities: | ||||||||||||
Net cash used in operating activities | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Purchases of marketable securities | ||||||||||||
67,153 | 88,993 | 102,277 | 140,203 | 133,185 | 130,175 | 0 | 0 | 0 | - | - | - | - |
Proceeds from maturities of marketable securities | ||||||||||||
100,100 | 118,837 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Purchases of property and equipment | ||||||||||||
312 | 314 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Net cash provided by (used in) investing activities | ||||||||||||
32,635 | 29,530 | 40,916 | -15,815 | -35,660 | -83,156 | 0 | 0 | 0 | - | - | - | - |
Cash flows from financing activities: | ||||||||||||
Proceeds from equity offering | ||||||||||||
- | 15,790 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Payment of offering costs | ||||||||||||
0 | - | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Proceeds from stock option exercises | ||||||||||||
988 | 508 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Net cash provided by financing activities | ||||||||||||
44,758 | 16,140 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Net increase (decrease) in cash and cash equivalents | ||||||||||||
14,968 | -4,350 | 5,117 | 22,418 | -3,157 | -53,258 | 0 | 0 | 0 | - | - | - | - |
Net cash provided by financing activities | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Net increase in cash and cash equivalents | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Supplemental disclosure of non-cash investing and financing activities: | ||||||||||||
Purchases of property and equipment included in accounts payable and accrued expenses | ||||||||||||
- | - | - | - | 0 | - | - | - | - | - | - | - | - |
Offering costs in accounts payable and accruals | ||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - |
Conversion of bridge units into preferred units | ||||||||||||
- | - | - | - | - | - | - | - | - | 8,500 | 0 | 0 | 0 |
Settlement of derivative liabilities upon issuance of preferred units | ||||||||||||
- | - | - | - | - | - | - | - | - | 944 | 0 | 0 | 0 |
Cumulative dividends on redeemable convertible preferred shares | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Accretion of redeemable convertible preferred units to redemption value | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Accretion of bridge units to redemption value | ||||||||||||
- | - | - | - | - | - | - | - | - | 576 | 0 | 0 | 0 |
Rights Offering [Member] | ||||||||||||
Proceeds from equity offering | ||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - |
Series C Preferred Stock [Member] | ||||||||||||
Proceeds from issuance of Series C Preferred Shares | ||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - |
Payment of offering costs | ||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - |
Series C issuance costs in accounts payable | ||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - |