| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
CASH FLOWS FROM OPERATING ACTIVITIES: | ||||||
Net loss | ||||||
-88,275 | -53,335 | -42,015 | -47,867 | - | - | - |
Net loss | ||||||
- | - | - | - | -53,260 | -23,873 | -6,832 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Non-cash restructuring charges | ||||||
- | - | - | 811 | - | - | - |
Stock-based compensation | ||||||
- | - | - | - | - | - | 22 |
Changes in fair value of warrant liabilities | ||||||
20,926 | - | - | - | 17,443 | 1,380 | 202 |
Securities issuance obligation | ||||||
10,485 | - | - | - | - | - | - |
Stock-based compensation | ||||||
5,695 | 6,796 | 5,905 | 5,510 | 3,186 | 302 | - |
Warrant issuance costs | ||||||
1,279 | - | - | - | - | - | - |
Term loan repayment fee | ||||||
438 | - | - | - | - | - | - |
Depreciation and amortization | ||||||
83 | 111 | 258 | 197 | 111 | 12 | 1 |
Noncash interest expense on short-term promissory notes and long-term note payable | ||||||
- | - | - | - | - | - | 2,760 |
Common stock issuance for milestone payment | ||||||
- | - | - | - | - | - | 57 |
Other | ||||||
-161 | 68 | -31 | -15 | -34 | 2 | - |
Changes in operating assets and liabilities: | ||||||
Prepaid expenses and other assets | ||||||
-336 | 1,341 | 115 | 362 | 1,087 | 531 | 10 |
Accrued, other and operating lease liabilities | ||||||
-2,034 | 2,770 | - | - | - | - | - |
Accrued liabilities | ||||||
- | - | 990 | -1,713 | 5,302 | 740 | 356 |
Accounts payable | ||||||
-277 | -48 | -1,217 | 2,246 | 6 | 186 | -89 |
Net cash used in operating activities | ||||||
-51,183 | -45,115 | -36,163 | -41,163 | - | - | - |
CASH FLOWS FROM INVESTING ACTIVITIES: | ||||||
Accrued interest | ||||||
- | - | - | - | - | - | -39 |
Net cash used in operating activities | ||||||
- | - | - | - | -28,265 | -21,786 | -3,572 |
Purchase of property and equipment | ||||||
39 | 118 | 92 | 214 | 414 | 187 | 2 |
Change in restricted cash | ||||||
- | - | - | - | 150 | 75 | - |
Proceeds from sale of property and equipment | ||||||
- | - | - | 43 | - | - | - |
Net cash used in investing activities | ||||||
-39 | -118 | -92 | -171 | - | - | - |
CASH FLOWS FROM FINANCING ACTIVITIES: | ||||||
Proceeds from public offering, net of offering costs | ||||||
97,731 | - | - | - | - | - | - |
Payment of term loan and repayment fee | ||||||
5,438 | - | - | - | - | - | - |
Proceeds from short-term convertible promissory notes | ||||||
- | - | - | - | - | - | 2,445 |
Proceeds from exercise of common stock options | ||||||
445 | 180 | 166 | 211 | 18 | 305 | 25 |
Proceeds from sale of short-term investments | ||||||
- | - | - | - | 10,031 | - | - |
Purchase of short-term investments | ||||||
- | - | - | - | 21 | 10,020 | - |
Net cash used in investing activities | ||||||
- | - | - | - | 9,446 | -10,282 | -2 |
Proceeds from issuance of common stock upon follow-on offering, net of offering costs | ||||||
- | 45,996 | 27,422 | - | - | - | - |
Proceeds from issuance of term loan, net of issuance costs | ||||||
- | 4,955 | - | - | - | - | - |
Payment of deferred offering costs | ||||||
- | - | - | 15 | 3,389 | 316 | - |
Net cash provided by financing activities | ||||||
92,738 | 51,131 | 27,588 | 196 | - | - | - |
Proceeds from issuance of common stock upon initial public offering, net of issuance costs | ||||||
- | - | - | - | 147,270 | - | - |
Proceeds from exercise of redeemable convertible preferred stock warrants | ||||||
- | - | - | - | 1,507 | - | - |
Proceeds from early exercise of stock options | ||||||
- | - | - | - | 13 | 100 | - |
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs | ||||||
- | - | - | - | - | 57,545 | 2,219 |
Repayment of stock subscription receivable | ||||||
- | - | - | - | - | 1,159 | - |
Net cash provided by financing activities | ||||||
- | - | - | - | 139,876 | 58,793 | 4,689 |
Effect of exchange rate changes on cash, cash equivalents and restricted cash | ||||||
-34 | -88 | -4 | -60 | - | - | - |
NET (DECREASE) IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH | ||||||
41,482 | 5,810 | -8,671 | -41,198 | - | - | - |
Effect of exchange rate changes on cash and cash equivalents | ||||||
- | - | - | - | -31 | - | - |
NET (DECREASE) INCREASE IN CASH AND CASH EQUIVALENTS | ||||||
- | - | - | - | 121,026 | 26,725 | 1,115 |
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION: | ||||||
Cash paid for (refund of) income taxes, net | ||||||
-69 | 15 | 260 | 107 | 8 | - | - |
Cash paid for interest | ||||||
336 | 87 | - | - | - | - | - |
Cash paid for interest | ||||||
- | - | - | - | - | - | 0 |
SUPPLEMENTAL DISCLOSURES OF NON-CASH INVESTING AND FINANCING INFORMATION: | ||||||
Right-of-use asset obtained in exchange for operating lease obligation | ||||||
771 | - | - | - | - | - | - |
Unpaid property and equipment in accrued and other liabilities | ||||||
- | - | 4 | 85 | 90 | 39 | - |
Unpaid deferred financing costs in accrued and other liabilities | ||||||
268 | - | - | - | - | - | - |
Issuance of common stock warrant | ||||||
- | 116 | - | - | - | - | - |
Change in redemption value of redeemable convertible preferred stock | ||||||
- | - | - | - | 374,015 | - | - |
Change in redemption value of redeemable convertible preferred stock | ||||||
- | - | - | - | - | -49,849 | -5,713 |
Conversion of preferred stock to common stock | ||||||
- | - | - | - | 539,151 | - | - |
Issuance of redeemable convertible preferred stock on exercise of warrants | ||||||
- | - | - | - | 19,253 | - | - |
Offering costs included in accounts payable and accrued liabilities | ||||||
- | - | - | - | 154 | 233 | - |
Conversion of short-term convertible promissory notes and accrued interest into Series C redeemable convertible preferred stock | ||||||
- | - | - | - | - | - | 5,383 |
Issuance of preferred stock warrants with redeemable convertible preferred stock | ||||||
- | - | - | - | - | - | 57 |
Settlement of premium conversion derivative in redeemable convertible preferred stock | ||||||
- | - | - | - | - | - | 2,415 |