| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | ||
|---|---|---|---|---|---|---|
Operating activities | ||||||
Net loss | ||||||
-75,438 | -62,279 | -54,010 | -47,743 | - | ||
Net loss | ||||||
- | - | - | - | -29,818 | ||
Adjustments to reconcile net loss to net cash provided by (used in) operating activities: | ||||||
Depreciation and amortization | ||||||
2,521 | 1,604 | 1,527 | 1,273 | 602 | ||
Amortization of financing right-of-use asset | ||||||
201 | - | - | - | - | ||
Gain on disposal of fixed assets and modification of lease | ||||||
181 | - | - | - | - | ||
Loss on disposal of fixed assets | ||||||
- | - | - | -4 | -17 | ||
Stock-based compensation expense | ||||||
9,839 | 6,610 | 4,419 | 4,234 | 3,233 | ||
Net amortization of premiums and discounts on marketable securities | ||||||
949 | 642 | 102 | -6 | - | ||
Changes in operating assets and liabilities: | ||||||
Prepaid expenses and other current assets | ||||||
783 | 500 | -131 | 508 | 390 | ||
Accounts receivable | ||||||
20,158 | - | -867 | 317 | - | ||
Other long-term assets | ||||||
- | 34 | 365 | 482 | - | ||
Restricted cash | ||||||
- | - | - | - | 413 | ||
Accounts payable | ||||||
1,493 | 888 | 141 | -404 | 2,022 | ||
Accrued expenses | ||||||
-3,576 | 4,191 | 3,533 | 3,685 | 1,663 | ||
Deferred revenue | ||||||
18,176 | 10,202 | -550 | - | - | ||
Proceeds for tenant improvement incentive from landlord | ||||||
7,237 | - | - | - | - | ||
Operating lease asset and liabilities | ||||||
-1,365 | - | - | - | - | ||
Deferred rent and lease incentive | ||||||
- | -355 | -320 | -284 | 54 | ||
Net cash provided by (used in) operating activities | ||||||
-60,253 | -40,315 | -44,729 | -40,536 | -23,030 | ||
Purchases of property and equipment | ||||||
12,638 | 1,384 | 821 | 2,322 | 1,176 | ||
Proceeds from the disposition of property and equipment | ||||||
110 | 9 | - | - | - | ||
Purchases of marketable securities | ||||||
108,206 | 96,768 | 41,770 | 25,020 | - | ||
Maturities of marketable securities | ||||||
109,000 | 87,500 | 27,000 | - | - | ||
Net cash provided by (used in) investing activities | ||||||
-11,734 | -10,643 | -15,591 | -27,342 | -1,176 | ||
Financing activities | ||||||
Payments on financing and capital lease obligations | ||||||
205 | 50 | 168 | - | - | ||
Payments on capital lease obligations | ||||||
- | - | - | 135 | 50 | ||
Proceeds from issuance of common stock through employee benefit plans | ||||||
211 | 626 | 1,799 | 395 | 392 | ||
Proceeds from issuance of common stock through exercise of warrants | ||||||
2 | - | - | - | - | ||
Proceeds from the issuance of common stock through employee stock purchase plan | ||||||
161 | - | - | - | - | ||
Proceeds from issuance of convertible preferred stock, net of issuance costs | ||||||
- | - | - | 39,813 | - | ||
Proceeds from issuance of common stock through at-the-market sales agreement, net of issuance costs | ||||||
824 | 16,538 | - | 50,484 | -620 | ||
Proceeds from issuance of common stock and accompanying warrants in public offerings and private placements, net of issuance costs | ||||||
60,359 | 51,970 | 32,306 | - | - | ||
Proceeds from issuance of convertible preferred stock and accompanying warrants in public offering, net of issuance costs | ||||||
4,638 | - | - | - | - | ||
Net cash provided by (used in) financing activities | ||||||
65,990 | 69,084 | 33,937 | 90,557 | -278 | ||
Increase (decrease) in cash, cash equivalents and restricted cash | ||||||
-5,997 | 18,126 | -26,383 | 22,679 | - | ||
(Decrease) increase in cash and cash equivalents | ||||||
- | - | - | - | -24,484 | ||
Supplemental disclosure of cash flow information: | ||||||
Cash paid for interest | ||||||
72 | 2 | 9 | 19 | 18 | ||
Cash paid for tax | ||||||
29 | 7 | - | - | - | ||
Non-cash investing and financing activities: | ||||||
Conversion of convertible preferred stock into common stock | ||||||
- | - | - | 82,013 | - | ||
Property and equipment received but unpaid as of period end | ||||||
1,565 | 268 | 143 | 349 | 1,359 | ||
Asset acquired under operating lease | ||||||
16,240 | - | - | - | - | ||
Assets acquired under financing lease | ||||||
1,059 | 28 | - | - | - | ||
Deferred financing costs incurred but unpaid as of period end | ||||||
58 | - | - | - | - | ||
Assets acquired under capital lease | ||||||
- | - | - | 17 | 389 | ||
Assets acquired through lease incentive | ||||||
- | - | - | - | 1,612 | ||
Offering costs incurred but unpaid as of period end | ||||||
23 | - | 13 | - | 1,280 | ||