| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
Revenue | ||||||
1,982 | 2,050 | 1,101 | 317 | - | - | |
Revenue | ||||||
- | - | - | - | 317 | - | |
Operating expenses: | ||||||
Research and development | ||||||
58,245 | 50,182 | 41,896 | 37,817 | 24,408 | 10,923 | |
General and administrative | ||||||
21,478 | 16,164 | 13,891 | 10,463 | 5,729 | 2,512 | |
Total operating expenses | ||||||
79,723 | 66,346 | 55,787 | 48,280 | 30,137 | 13,435 | |
Loss from operations | ||||||
-77,741 | -64,296 | -54,686 | -47,963 | -29,820 | -13,435 | |
Other income, net | ||||||
2,303 | 2,017 | 676 | 220 | 2 | 4 | |
Net loss | ||||||
- | - | - | -47,743 | -29,818 | -13,431 | |
Accrued dividends on preferred stock | ||||||
- | - | - | 3,681 | 4,934 | 2,211 | |
Net loss applicable to common stockholders | ||||||
-75,438 | -62,279 | -54,010 | -51,424 | -34,752 | -15,642 | |
Net loss per share applicable to common stockholders - basic and diluted | ||||||
-1.88 | -1.91 | -2.13 | -4.05 | -17.55 | -10.26 | |
Weighted-average number of common shares used in net loss per share applicable to common stockholders - basic and diluted | ||||||
40,222 | 32,656 | 25,406 | 12,696 | 1,980 | 1,525 | |