| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 |
|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||||
Net loss | ||||||||
-94,377 | -113,293 | -88,294 | -109,713 | -109,384 | -97,395 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||
Depreciation and amortization expense | ||||||||
5,058 | 4,732 | 3,869 | 3,354 | 3,330 | 2,841 | 0 | 0 | 0 |
Stock-based compensation expense | ||||||||
12,547 | 11,334 | 10,048 | 8,584 | 7,909 | 7,333 | 0 | 0 | 0 |
Change in fair value of contingent consideration | ||||||||
-21,141 | 13 | -17,812 | 28,851 | 31,814 | 25,020 | 0 | 0 | 0 |
Deferred income tax benefit | ||||||||
- | -486 | -925 | -3,449 | -4,948 | -5,565 | 0 | 0 | 0 |
Accretion of discount on short-term investments | ||||||||
- | - | - | - | - | - | - | 0 | 0 |
Changes in operating assets and liabilities: | ||||||||
Collaboration receivables | ||||||||
0 | - | - | - | 0 | - | - | - | - |
Prepaid expenses and other assets | ||||||||
8,607 | 8,495 | 4,529 | 603 | -348 | 1,346 | 0 | 0 | 0 |
Right-of-use assets | ||||||||
-501 | -484 | 0 | 0 | 0 | - | - | - | - |
Accounts payable | ||||||||
1,431 | 9,928 | 511 | -2,281 | -1,921 | 658 | 0 | 0 | 0 |
Accrued expenses | ||||||||
912 | 257 | 3,121 | 2,605 | 3,604 | 2,271 | 0 | 0 | 0 |
Deferred rent | ||||||||
- | - | - | - | - | 470 | 0 | 0 | 0 |
Lease liability | ||||||||
-411 | -375 | 0 | 0 | 0 | - | - | - | - |
Deferred revenue | ||||||||
-1,636 | -1,057 | 0 | 0 | 0 | - | - | - | - |
Net cash used in operating activities | ||||||||
-92,078 | -82,162 | -78,144 | -29,997 | -26,731 | -22,133 | 0 | 0 | 0 |
Cash flows from investing activities: | ||||||||
Purchases of investments | ||||||||
0 | - | - | - | - | 136,694 | 0 | 0 | 0 |
Sales and maturities of investments | ||||||||
204,711 | 159,622 | 158,297 | 98,822 | 76,971 | 57,984 | 0 | 0 | 0 |
Purchases of property and equipment | ||||||||
4,823 | 3,537 | 3,254 | 3,616 | 4,713 | 6,580 | 0 | 0 | 0 |
Net cash provided by investing activities | ||||||||
-1,792 | -18,186 | 8,506 | -73,926 | -58,436 | -85,290 | 0 | 0 | 0 |
Cash flows from financing activities: | ||||||||
Payments of public offering costs | ||||||||
0 | - | - | - | - | - | - | - | - |
Payments of initial public offering costs | ||||||||
- | - | - | - | - | 4,102 | 0 | 0 | 0 |
Proceeds from option exercises | ||||||||
747 | 1,512 | 0 | 0 | 0 | - | - | - | - |
Net cash provided by financing activities | ||||||||
128,832 | 129,654 | 129,629 | 161,316 | 115,859 | 113,623 | 0 | 0 | 0 |
Net increase in cash, cash equivalents and restricted cash | ||||||||
34,962 | 29,306 | 59,991 | 57,393 | 30,692 | 6,200 | 0 | 0 | 0 |
Supplemental disclosure of non-cash investing and financing activities: | ||||||||
Purchases of property and equipment included in accounts payable and accrued expenses | ||||||||
1,858 | 1,189 | -312 | -381 | -572 | 49 | 0 | 0 | 0 |
Deferred offering costs included in accounts payable and accrued expenses | ||||||||
0 | - | - | - | - | - | 0 | 0 | 0 |
Accretion of redeemable convertible preferred stock to redemption value | ||||||||
- | - | - | - | - | 644 | 0 | 0 | 0 |